Rebecca Ellston - AILBRY - Article Search

Results for 'Rebecca Ellston' :

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Publication Year: 2005

DOI: https://doi.org/10.1016/j.bmcl.2005.11.053

Abstract:

Authors:
- Nicola M. Heron
- Malcolm Anderson
- David P. Blowers
- J. Breed
- Jonathan Eden
- Stephen Green
- George B. Hill
- Trevor Johnson
- Frédéric Jung
- Helen McMiken
- Andrew A. Mortlock
- Andrew Pannifer
- Richard A. Pauptit
- Jennifer H. Pink
- Nicola Roberts
- Siân Rowsell
Abstract 3264: AZD8186: a potent selective inhibitor of PI3Kβ targeting PTEN-deficient tumours dependent on dysregulated PI3Kβ signalling.

Publication Year: 2013

DOI: https://doi.org/10.1158/1538-7445.am2013-3264

Abstract:

Authors:
- Urs J. Hancox
- Sabina Cosulich
- Hannah Dry
- Lynsey Hanson
- Clare Crafter
- Bernard Barlaam
- Martina Fitzek
- Lara Ward
- Marie Cumberbatch
- Steve Powell
- Rebecca Ellston
- Mandy Lawson
- Stephen R. Wedge
- Liz Harrington
- Stephen Green
- Simon T. Barry
Abstract 5409: AZD1152-hQPA Accurins: Nanoparticle formulations showing extended release and the potential for improved therapeutic index

Publication Year: 2014

DOI: https://doi.org/10.1158/1538-7445.am2014-5409

Abstract:

Authors:
- Simon T. Barry
- Elaine Cadogan
- Rajesh Odedra
- Susan Ashton
- John R. Foster
- Young Ho Song
- Susan C. Low
- Paula Taylor
- Rebecca Ellston
- Urszula M. Polanska
- Joanne Wilson
- Colin Howes
- Dawn Trueman
- Mike Walker
- David De Witt
- Marianne Ashford
- Jeff Hrkach
- Phil Jewsbury
Abstract 2665: High dose intermittent scheduling of AZD8835, a novel potent and selective inhibitor of PI3Kα and PI3Kδ, identifies potential treatment strategies for PIK3CA-dependent cancers

Publication Year: 2015

DOI: https://doi.org/10.1158/1538-7445.am2015-2665

Abstract:

Authors:
- Kevin Hudson
- Urs J. Hancox
- Cath Trigwell
- Phillippa Dudley
- Lyndsey Hanson
- Robert McEwen
- Alys Jones
- Marie Cumberbatch
- Urszula M. Polanska
- Rebecca Ellston
- Oona Delpuech
- Pablo Morentin Gutierrez
- Lara Ward
- Francisco Cruzalegui
- Stephen Green
Discovery of AZD3147: A Potent, Selective Dual Inhibitor of mTORC1 and mTORC2

Publication Year: 2015

DOI: https://doi.org/10.1021/jm501778s

Abstract:

Authors:
- Kurt G. Pike
- Jeff Morris
- Linette Ruston
- Sarah L. Pass
- Ryan Greenwood
- Emma Williams
- Julie Demeritt
- Janet D. Culshaw
- Kristy Gill
- Martin Pass
- M. Raymond V. Finlay
- Catherine J. Good
- Craig Roberts
- Gordon S. Currie
- Kevin Blades
- Jonathan Eden
- Stuart E. Pearson
Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition

Publication Year: 2016

DOI: https://doi.org/10.1177/0192623316629805

Abstract:

Authors:
- Alison Bigley
- Stéphanie Klein
- Barry R. Davies
- Leigh Williams
- Daniel G. Rudmann
Abstract 3769: Continuous, low intensity systemic dosing maximizes the therapeutic margin of Eg5/KSP inhibition in an orthotopic model of urothelial cell carcinoma

Publication Year: 2016

DOI: https://doi.org/10.1158/1538-7445.am2016-3769

Abstract:

Authors:
- Leigh Williams
- Rebecca Ellston
- Dawn Trueman
- Helen Musgrove
- Linette Ruston
- Brian Aquila
- Elizabeth J. Pease
- Stéphanie Klein
- Barry R. Davies
Abstract A24: Comprehensive PI3K pathway inhibition through combination of the PI3Kβ/δ inhibitor AZD8186 and the mTORC1/2 inhibitor AZD2014 drives tumor regression in vivo

Publication Year: 2015

DOI: https://doi.org/10.1158/1538-8514.pi3k14-a24

Abstract:

Authors:
- Urs J. Hancox
- Urszula M. Polanska
- Lyndsay Hanson
- Rebecca Ellston
- Julia Maynard
- Manfred Kraus
- Jon Curwen
- Teresa Klinowska
- Lara Ward
- Francisco Cruzalegui
- Stephen Green
- Stefan N. Symeonides
- Kathryn Cronin
- Simon T. Barry
Abstract 4249: The Pi3Kβ/δ inhibitor AZD8186 has potential to treat tumours in combination with key signalling pathway inhibitors

Publication Year: 2014

DOI: https://doi.org/10.1158/1538-7445.am2014-4249

Abstract:

Authors:
- Simon T. Barry
- Kathryn Cronin
- Marie Cumberbatch
- Rebecca Ellston
- Emily Foster
- Urs J. Hancox
- Lyndsey Hanson
- Liz Harrington
- Carol Lenaghan
- Stefan N. Symeonides
- Cath Trigwell
- Lara Ward
Abstract PR12: Discovery and preclinical evaluation of cEt-modified KRAS antisense oligonucleotide inhibitors

Publication Year: 2015

DOI: https://doi.org/10.1158/1535-7163.targ-15-pr12

Abstract:

Authors:
- Alexey S. Revenko
- Sarah J. Ross
- Lyndsey Hanson
- Rebecca Ellston
- Chris May
- Sanjay K. Pandey
- Linda K. Buckett
- Stéphanie Klein
- Mitchell Revill
- Kevin Hudson
- Brett P. Monia
- David C. Blakey
- Paul D. Lyne
- A. Robert MacLeod

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AILBRY - Article Search

Results for 'Rebecca Ellston' :

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Abstract 3264: AZD8186: a potent selective inhibitor of PI3Kβ targeting PTEN-deficient tumours dependent on dysregulated PI3Kβ signalling.

Abstract 5409: AZD1152-hQPA Accurins: Nanoparticle formulations showing extended release and the potential for improved therapeutic index

Abstract 2665: High dose intermittent scheduling of AZD8835, a novel potent and selective inhibitor of PI3Kα and PI3Kδ, identifies potential treatment strategies for PIK3CA-dependent cancers

Discovery of AZD3147: A Potent, Selective Dual Inhibitor of mTORC1 and mTORC2

Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition

Abstract 3769: Continuous, low intensity systemic dosing maximizes the therapeutic margin of Eg5/KSP inhibition in an orthotopic model of urothelial cell carcinoma

Abstract A24: Comprehensive PI3K pathway inhibition through combination of the PI3Kβ/δ inhibitor AZD8186 and the mTORC1/2 inhibitor AZD2014 drives tumor regression in vivo

Abstract 4249: The Pi3Kβ/δ inhibitor AZD8186 has potential to treat tumours in combination with key signalling pathway inhibitors

Abstract PR12: Discovery and preclinical evaluation of cEt-modified KRAS antisense oligonucleotide inhibitors

What is Boolean Searches

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