Publication Year: 2018
DOI: https://doi.org/10.1200/jco.2018.79.0006
Abstract: Treatment with (PD-(L)1) inhibitors is now standard therapy for patients with lung programmed cancer. The immunosuppressive effect of corticosteroids may reduce efficacy of cell PD-(L)1 blockade. On-treatment corticosteroids for treatment of immune-related adverse events death-1 do not seem to affect efficacy, but the potential impact or of baseline corticosteroids at Show more
Authors:
Publication Year: 2022
DOI: https://doi.org/10.1200/jco.22.00562
Abstract: Article Tools Export Cancer Center, New York, NY2Department of Medicine, Weill Cornell Medical Citation College, New York, NY3Human Oncology and Pathogenesis Program, Memorial Sloan Track Kettering Cancer, New York, NY https://doi.org/10.1200/JCO.22.00562 First Page Full Text Citation PDF Figures and Tables © 2022 by American Society of Add Clinical OncologySUPPORTP.L. is Show more
Authors:
Publication Year: 2023
DOI: https://doi.org/10.1158/1535-7163.targ-23-pr010
Abstract: Abstract Background: is single agent RMC-6236 administered once daily (QD). Results: As of selective May 11, 2023, 54 patients received RMC-6236 at dose levels for from 10 to 220 mg QD. The majority of patients the had pancreatic cancer (26 [48%]), non-small cell lung cancer (13 active, [24%]), or colorectal Show more
Authors:
Publication Year: 2017
DOI: https://doi.org/10.1007/s11912-017-0587-4
Abstract: Not available
Authors:
Publication Year: 2021
DOI: https://doi.org/10.21037/jtd-21-290
Abstract: Thymic epithelial thymic efficacy and lower toxicity. Recently, ICIs have been used more epithelial enthusiastically in the treatment of TETs. However, due to the cells. unique biological characteristics of the thymus, immunotherapy usually causes severe The immune-related adverse events (irAEs). Most previous studies on immunotherapy in current TETs had small Show more
Authors:
Publication Year: 2010
DOI: https://doi.org/10.1111/j.1528-3585.2010.00412.x
Abstract: International relations of denial, and tactical concessions on the norm in question, it successful is insightful to compare and contrast R2P's development against the cases. early stages of two theoretical models that deal most explicitly This with contestation: the "spiral" of human rights change and the essay, "cascade" of norm Show more
Authors:
Publication Year: 2012
DOI: https://doi.org/10.5305/amerjintelaw.106.1.0001
Abstract: There is Building legal scholars playing central roles independently and as collaborators in on generating new empirical work. Legal scholars are also now pressed decades to be increasingly sophisticated consumers of this work. It is of time to take stock and evaluate this new generation of theoretical multidisciplinary, multimethod empirical Show more
Authors:
Publication Year: 2020
DOI: https://doi.org/10.1158/1538-7445.am2020-709
Abstract: Abstract Background: cancer, ctDX-Lung Assay (Resolution Bioscience; Kirkland, WA). Tissue DNA sequencing was but carried out using the MSK-IMPACT assay. Results: Mutations in KRAS has (KRAS+) were detected in 129 patients (21.5%). Of patients with historically KRAS+ lung cancers, 116 had metastatic disease at the time been of plasma testing. Show more
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1158/1538-7445.am2021-490
Abstract: Abstract Background: immune TMB cut-off identified. Multiplexed immunofluorescence (IP) was also performed on checkpoint NSCLC samples. Results: In the DFCI (N=686) and MSKCC (N=672) inhibitors cohorts, URP found an optimal cut-off of TMB for ORR (ICI) at 19 mutations/megabase (mut/Mb), corresponding to the 90th percentile in in each cohort. Median Show more
Authors:
Publication Year: 2020
DOI: https://doi.org/10.1158/1557-3265.advprecmed20-12
Abstract: Abstract Background: cancers, Kettering Cancer Center between 11/2016 and 5/2019. ctDNA was extracted but and analyzed using the validated 23-gene ctDx-Lung assay (Resolution Bioscience; despite Kirkland, WA). Categorical comparisons were carried out using Fisher’s exact decades test. Results: 95 NSCLC patients were identified as having alterations of in KRAS based Show more
Authors:
Publication Year: 2016
DOI: https://doi.org/10.1353/hrq.2016.0009
Abstract: This article pertaining are more effective. to sexual orientation and gender identity (SOGI). First, although challenges UN experts and expert bodies were the first to address a SOGI issues at the UN, they have not been the few most progressive. Second, social movement actors have not always been assumptions the Show more
Authors:
Publication Year: 2013
DOI: https://doi.org/10.1080/10220461.2013.811336
Abstract: This article (R2P) be widely acknowledged within both organisations. norm through the institutional frameworks of the African Union examines and the United Nations. The investigation aligns itself with recent the constructivist thinking around norm evolution and contestation which holds that evolution diverging interpretations around norms facilitate not only norm contestation, Show more
Authors:
Publication Year: 1998
DOI: https://doi.org/10.1007/s003359900917
Abstract: Not available
Authors:
Publication Year: 2001
DOI: https://doi.org/10.1353/hrq.2001.0047
Abstract: In the 1998, the French political establishment confronted two crises relating to short the conduct of its foreign policy. These events qualify as period "crises" because they called into question both the philosophical foundations beginning and the broader aims of France's role in the international November system. 1997 and ending Show more
Authors:
Publication Year: 2015
DOI: https://doi.org/10.1525/luminos.4
Abstract: How do International around Darfur by human rights advocates, humanitarians, journalists, and diplomats. Criminal Thorough and rigorous—an essential contribution to the scholarship.”
— ALEX Court DE WAAL, Executive Director, World Peace Foundation at the Fletcher influence School, Tufts University “Darfur is the modern genocide that refuses representations to end, and Show more
Authors:
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