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Results for 'Integrase Inhibitors'
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Integrase inhibitors to treat HIV/Aids
Publication Year: 2005
DOI: https://doi.org/10.1038/nrd1660
Abstract:
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Authors:
Yves Pommier
Allison A. Johnson
Christophe Marchand
Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection
Publication Year: 2008
DOI: https://doi.org/10.1021/jm800245z
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Authors:
Vincenzo Summa
Alessia Petrocchi
Fabio Bonelli
Benedetta Crescenzi
Monica Donghi
Marco Ferrara
F. Fiore
Cristina Gardelli
Odalys Gonzalez Paz
Daria J. Hazuda
Philip Jones
Olaf Kinzel
Ralph Laufer
Edith Monteagudo
Ester Muraglia
Emanuela Nizi
Federica Orvieto
Paola Pace
Giovanna Pescatore
Rita Scarpelli
Kara A. Stillmock
Marc Witmer
Michael Rowley
Novel HIV-1 Integrase Inhibitors Derived from Quinolone Antibiotics
Publication Year: 2006
DOI: https://doi.org/10.1021/jm0600139
Abstract:
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Authors:
Motohide Sato
Takahisa Motomura
Hisateru Aramaki
Takashi Matsuda
Masaki Yamashita
Yoshiharu Ito
Ryoji Tsuboi
Yumi Matsuzaki
Wataru Watanabe
Kazunobu Yamataka
Satoru Ikeda
Eiichi Kodama
Masao Matsuoka
Hiroyuki Shinkai
<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor
Publication Year: 2011
DOI: https://doi.org/10.1128/aac.01209-10
Abstract:
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Authors:
Masanori Kobayashi
Tomokazu Yoshinaga
Takahiro Seki
Chiaki Wakasa-Morimoto
Kevin Brown
Robert G. Ferris
Scott A. Foster
Richard Hazen
Shigeru Miki
Akemi Suyama-Kagitani
Shinobu Kawauchi-Miki
Teruhiko Taishi
Takashi Kawasuji
Brian A. Johns
Mark Underwood
Edward P. Garvey
Akihiko Sato
Tamio Fujiwara
<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor
Publication Year: 2010
DOI: https://doi.org/10.1128/aac.01209-10
Abstract:
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Authors:
Masanori Kobayashi
Tomokazu Yoshinaga
Takahiro Seki
Chiaki Wakasa-Morimoto
Kevin Brown
Robert G. Ferris
Scott A. Foster
Richard Hazen
Shigeru Miki
Akemi Suyama-Kagitani
Shinobu Kawauchi-Miki
Teruhiko Taishi
Takashi Kawasuji
Brian A. Johns
Mark Underwood
Edward P. Garvey
Akihiko Sato
Tamio Fujiwara
Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques
Publication Year: 2004
DOI: https://doi.org/10.1126/science.1098632
Abstract:
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Authors:
Daria J. Hazuda
Steven D. Young
James P. Guare
Neville J. Anthony
Robert Gomez
John Wai
Joseph P. Vacca
Larry Handt
Sherri L. Motzel
Hilton J. Klein
Geethanjali Dornadula
Robert M. Danovich
Marc Witmer
Keith A. Wilson
Lynda Tussey
William A. Schleif
Lori S. Gabryelski
Lixia Jin
Michael D. Miller
Danilo R. Casimiro
Emilio A. Emini
John W. Shiver
Dolutegravir versus raltegravir in antiretroviral-experienced, integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING study
Publication Year: 2013
DOI: https://doi.org/10.1016/s0140-6736(13)61221-0
Abstract:
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Authors:
Pedro Cahn
Anton Pozniak
Horacio Mingrone
А A Shuldyakov
Carlos Brites
Jaime Andrade‐Villanueva
Gary Richmond
Carlos Beltran Buendia
Jan Fourie
Moti Ramgopal
Debbie Hagins
Franco Felizarta
José Valdez Madruga
Tânia Reuter
Tamara Newman
Catherine B. Small
John Lombaard
Beatriz Grinsztejn
David Dorey
Mark Underwood
Sandy Griffith
Sherene Min
Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial
Publication Year: 2007
DOI: https://doi.org/10.1016/s0140-6736(07)60597-2
Abstract:
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Authors:
Beatriz Grinsztejn
Bach Nguyen
Christine Katlama
José Ramón Arribas
Adriano Lazzarin
Daniel Vittecoq
Charles J. Gonzalez
Joshua Chen
Charlotte M. Harvey
Robin Isaacs
HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase
Publication Year: 2000
DOI: https://doi.org/10.1073/pnas.200139397
Abstract:
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Authors:
Amy S. Espeseth
Peter Felock
Abigail Wolfe
Marc Witmer
Jay A. Grobler
Neville J. Anthony
Melissa S. Egbertson
Jeffrey Y. Melamed
Steve Young
Terence G. Hamill
James L. Cole
Daria J. Hazuda
HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications
Publication Year: 2011
DOI: https://doi.org/10.1093/infdis/jir025
Abstract:
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Authors:
José-Luís Blanco
Vici Varghese
Soo‐Yon Rhee
José Ramón Arribas
Robert W. Shafer
Weight gain and integrase inhibitors
Publication Year: 2020
DOI: https://doi.org/10.1097/qco.0000000000000616
Abstract:
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Authors:
Allison Ross Eckard
Grace A. McComsey
Pharmacokinetics and Safety of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor, in Healthy Volunteers
Publication Year: 2010
DOI: https://doi.org/10.1128/aac.00842-09
Abstract:
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Authors:
Sherene Min
Ivy Song
Julie Borland
Shuguang Chen
Yu Lou
Tamio Fujiwara
Stephen C. Piscitelli
Clinical Pharmacokinetic, Pharmacodynamic and Drug-Interaction Profile of the Integrase Inhibitor Dolutegravir
Publication Year: 2013
DOI: https://doi.org/10.1007/s40262-013-0093-2
Abstract:
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Authors:
Mackenzie L. Cottrell
Tanja Hadzic
Angela D. M. Kashuba
Raltegravir: The First HIV Type 1 Integrase Inhibitor
Publication Year: 2009
DOI: https://doi.org/10.1086/597290
Abstract:
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Authors:
David M. Margolis
Roy M. Gulick
Rapid and Durable Antiretroviral Effect of the HIV-1 Integrase Inhibitor Raltegravir as Part of Combination Therapy in Treatment-Naive Patients With HIV-1 Infection
Publication Year: 2007
DOI: https://doi.org/10.1097/qai.0b013e318157131c
Abstract:
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Authors:
Martin Markowitz
Bach‐Yen Nguyen
Eduardo Gotuzzo
Fernando Mendo
Winai Ratanasuwan
Colin Kovacs
Guillermo Prada
Javier Morales-Ramírez
Clyde S. Crumpacker
Robin Isaacs
Lucinda R. Gilde
Hong Wan
Michael D. Miller
Larissa Wenning
Hedy Teppler
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