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Results for 'INHA'
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<i>inhA</i> , a Gene Encoding a Target for Isoniazid and Ethionamide in <i>Mycobacterium tuberculosis</i>
Publication Year: 1994
DOI: https://doi.org/10.1126/science.8284673
Abstract:
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Authors:
Asesh Banerjee
David Dubnau
Annaık̈ Quémard
V. Balasubramanian
Kyung Sun Um
Theresa Wilson
Desmond M. Collins
G. de Lisle
William R. Jacobs
Modification of the NADH of the Isoniazid Target (InhA) from<i>Mycobacterium tuberculosis</i>
Publication Year: 1998
DOI: https://doi.org/10.1126/science.279.5347.98
Abstract:
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Authors:
Denise A. Rozwarski
Gregory A. Grant
D. H. R. BARTON
William R. Jacobs
James C. Sacchettini
Genetic Evidence that InhA of <i>Mycobacterium smegmatis</i> Is a Target for Triclosan
Publication Year: 1999
DOI: https://doi.org/10.1128/aac.43.3.711
Abstract:
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Authors:
Laura M. McMurry
Patrick F. McDermott
Stuart B. Levy
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the <i>Mycobacterium tuberculosis</i> enoyl reductase: Adduct affinity and drug resistance
Publication Year: 2003
DOI: https://doi.org/10.1073/pnas.2235848100
Abstract:
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Authors:
Richa Rawat
Adrian Whitty
Peter J. Tonge
Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate
Publication Year: 1999
DOI: https://doi.org/10.1074/jbc.274.22.15582
Abstract:
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Authors:
Denise A. Rozwarski
Catherine Vilchèze
Michele Sugantino
Robert Bittman
James C. Sacchettini
Inhibition of InhA, the Enoyl Reductase from <i>Mycobacterium tuberculosis</i>, by Triclosan and Isoniazid
Publication Year: 2000
DOI: https://doi.org/10.1021/bi0008940
Abstract:
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Authors:
S. Parikh
Guoping Xiao
Peter J. Tonge
Characterization of the Catalase-Peroxidase Gene (katG) and inhA Locus in Isoniazid-Resistant and -Susceptible Strains of Mycobacterium tuberculosis by Automated DNA Sequencing: Restricted Array of Mutations Associated with Drug Resistance
Publication Year: 1996
DOI: https://doi.org/10.1093/infdis/173.1.196
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Authors:
James M. Musser
Vivek Kapur
Diana L. Williams
Barry N. Kreiswirth
Dick van Soolingen
J D van Embden
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
Publication Year: 2006
DOI: https://doi.org/10.1038/nm1466
Abstract:
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Authors:
Catherine Vilchèze
Feng Wang
Masayoshi Arai
Manzour Hernando Hazbón
Roberto Colangeli
Laurent Kremer
Torin R. Weisbrod
David Alland
James C. Sacchettini
William R. Jacobs
High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of <i>Mycobacterium tuberculosis</i>
Publication Year: 2006
DOI: https://doi.org/10.1021/cb0500042
Abstract:
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Authors:
Todd J. Sullivan
J.J. Truglio
Melissa E. Boyne
Polina Novichenok
Xujie Zhang
Christopher F. Stratton
Huei-Jiun Li
Tejinder Kaur
Amol Amin
Francis Johnson
Richard A. Slayden
Caroline Kisker
Peter J. Tonge
<i>ethA</i> , <i>inhA</i> , and <i>katG</i> Loci of Ethionamide-Resistant Clinical <i>Mycobacterium tuberculosis</i> Isolates
Publication Year: 2003
DOI: https://doi.org/10.1128/aac.47.12.3799-3805.2003
Abstract:
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Authors:
Glenn P. Morlock
Beverly Metchock
David Sikes
Jack T. Crawford
Robert C. Cooksey
InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II
Publication Year: 2000
DOI: https://doi.org/10.1099/00221287-146-2-289
Abstract:
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Authors:
Hédia Marrakchi
Gilbert Lanéelle
Annaık̈ Quémard
Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis
Publication Year: 1995
DOI: https://doi.org/10.1128/aac.39.11.2472
Abstract:
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Authors:
D A Rouse
Z Li
Gill Han Bai
Sheldon L. Morris
A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis
Publication Year: 2010
DOI: https://doi.org/10.1074/jbc.m109.090373
Abstract:
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Authors:
Sylvia R. Luckner
Nina Liu
Christopher W. am Ende
Peter J. Tonge
Caroline Kisker
Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
Publication Year: 2007
DOI: https://doi.org/10.1016/j.bmc.2007.08.013
Abstract:
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Authors:
Xin He
Akram Alian
Paul R. Ortiz de Montellano
Inactivation of the <i>inhA</i> -Encoded Fatty Acid Synthase II (FASII) Enoyl-Acyl Carrier Protein Reductase Induces Accumulation of the FASI End Products and Cell Lysis of <i>Mycobacterium smegmatis</i>
Publication Year: 2000
DOI: https://doi.org/10.1128/jb.182.14.4059-4067.2000
Abstract:
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Authors:
Catherine Vilchèze
Héctor R. Morbidoni
Torin R. Weisbrod
Hiroyuki Iwamoto
Mack Kuo
James C. Sacchettini
William R. Jacobs
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