Title: MicroRNA-29c-3p é regulado por concentração elevada de glicose e reduz a migração de fibroblastos dérmicos humanos em matriz de colágeno.
Abstract: reduced by miR-29c, accompanied by an increase in cell adhesion to collagen I and a reduction in protein expression of β1 integrin, a potential miR-29c target.In conclusion, high glucose increases miR-29c expression in human fibroblasts, contributing to deficient migration, potentially through its direct target β1 integrin.This effect may contribute to the impaired wound healing observed in diabetic patients.