Publication Information

{'id': 'https://openalex.org/W4319311304', 'doi': 'https://doi.org/10.1016/j.pediatrneurol.2023.01.018', 'title': 'Twelve-Month Efficacy of Lacosamide Monotherapy at Maximal Dose and Tolerability for Epilepsy Treatment in Pediatric Patients: Real-World Clinical Experience', 'display_name': 'Twelve-Month Efficacy of Lacosamide Monotherapy at Maximal Dose and Tolerability for Epilepsy Treatment in Pediatric Patients: Real-World Clinical Experience', 'publication_year': 2023, 'publication_date': '2023-02-06', 'ids': {'openalex': 'https://openalex.org/W4319311304', 'doi': 'https://doi.org/10.1016/j.pediatrneurol.2023.01.018', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36868054'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.pediatrneurol.2023.01.018', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S165686931', 'display_name': 'Pediatric Neurology', 'issn_l': '0887-8994', 'issn': ['0887-8994', '1873-5150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017486387', 'display_name': 'Ting Zhao', 'orcid': 'https://orcid.org/0000-0003-3502-6043'}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ting Zhao', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100695816', 'display_name': 'Hongjian Li', 'orcid': 'https://orcid.org/0000-0002-3372-6655'}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hong-jian Li', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028040749', 'display_name': 'Huilan Zhang', 'orcid': 'https://orcid.org/0000-0002-2366-7321'}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hui-lan Zhang', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100731462', 'display_name': 'Jing Yu', 'orcid': 'https://orcid.org/0000-0003-2809-3547'}, 'institutions': [{'id': 'https://openalex.org/I4210144404', 'display_name': 'Beijing Children’s Hospital', 'ror': 'https://ror.org/04skmn292', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jing Yu', 'raw_affiliation_strings': ["Department of Neurology, Children's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Neurology, Children's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210144404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102937592', 'display_name': 'Jie Feng', 'orcid': 'https://orcid.org/0009-0008-6338-5178'}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jie Feng', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100447703', 'display_name': 'Tingting Wang', 'orcid': 'https://orcid.org/0000-0001-6541-2098'}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ting-ting Wang', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101569181', 'display_name': 'Yan Sun', 'orcid': 'https://orcid.org/0000-0002-4113-2929'}, 'institutions': [{'id': 'https://openalex.org/I4210144404', 'display_name': 'Beijing Children’s Hospital', 'ror': 'https://ror.org/04skmn292', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144404']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yan Sun', 'raw_affiliation_strings': ["Department of Neurology, Children's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Neurology, Children's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210144404']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100538861', 'display_name': 'Lu‐hai Yu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210122141', 'display_name': "People's Hospital of Xinjiang Uygur Autonomous Region", 'ror': 'https://ror.org/02r247g67', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122141']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Lu-hai Yu', 'raw_affiliation_strings': ["Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}, {'raw_affiliation_string': "Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China", 'institution_ids': ['https://openalex.org/I4210122141']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5101569181', 'https://openalex.org/A5100538861'], 'corresponding_institution_ids': ['https://openalex.org/I4210144404', 'https://openalex.org/I4210122141'], 'apc_list': {'value': 3100, 'currency': 'USD', 'value_usd': 3100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.875, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.728004, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 81}, 'biblio': {'volume': '142', 'issue': None, 'first_page': '23', 'last_page': '30'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10094', 'display_name': 'Epilepsy and Seizures', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10094', 'display_name': 'Epilepsy and Seizures', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12229', 'display_name': 'Prenatal Exposure to Antiepileptic Drugs', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10570', 'display_name': 'Mechanisms of Multidrug Resistance in Cancer', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/lacosamide', 'display_name': 'Lacosamide', 'score': 0.96060437}, {'id': 'https://openalex.org/keywords/tolerability', 'display_name': 'Tolerability', 'score': 0.9272442}, {'id': 'https://openalex.org/keywords/pediatric-epilepsy', 'display_name': 'Pediatric epilepsy', 'score': 0.54021424}, {'id': 'https://openalex.org/keywords/combination-therapy', 'display_name': 'Combination therapy', 'score': 0.50714207}, {'id': 'https://openalex.org/keywords/epilepsy', 'display_name': 'Epilepsy', 'score': 0.482343}], 'concepts': [{'id': 'https://openalex.org/C2778139780', 'wikidata': 'https://www.wikidata.org/wiki/Q420077', 'display_name': 'Lacosamide', 'level': 3, 'score': 0.96060437}, {'id': 'https://openalex.org/C2778375690', 'wikidata': 'https://www.wikidata.org/wiki/Q7814214', 'display_name': 'Tolerability', 'level': 3, 'score': 0.9272442}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8912076}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.6567223}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.56104076}, {'id': 'https://openalex.org/C3018325526', 'wikidata': 'https://www.wikidata.org/wiki/Q5382985', 'display_name': 'Pediatric epilepsy', 'level': 3, 'score': 0.54021424}, {'id': 'https://openalex.org/C2776999253', 'wikidata': 'https://www.wikidata.org/wiki/Q1304270', 'display_name': 'Combination therapy', 'level': 2, 'score': 0.50714207}, {'id': 'https://openalex.org/C167135981', 'wikidata': 'https://www.wikidata.org/wiki/Q2146302', 'display_name': 'Retrospective cohort study', 'level': 2, 'score': 0.4866129}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.44662884}, {'id': 'https://openalex.org/C61511704', 'wikidata': 'https://www.wikidata.org/wiki/Q1671857', 'display_name': 'Incidence (geometry)', 'level': 2, 'score': 0.43204302}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.37234405}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004827', 'descriptor_name': 'Epilepsy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004827', 'descriptor_name': 'Epilepsy', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000078334', 'descriptor_name': 'Lacosamide', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000078334', 'descriptor_name': 'Lacosamide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.pediatrneurol.2023.01.018', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S165686931', 'display_name': 'Pediatric Neurology', 'issn_l': '0887-8994', 'issn': ['0887-8994', '1873-5150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36868054', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.6}], 'grants': [{'funder': 'https://openalex.org/F4320328898', 'funder_display_name': 'Natural Science Foundation of Xinjiang', 'award_id': '2022D01C154'}], 'datasets': [], 'versions': [], 'referenced_works_count': 22, 'referenced_works': ['https://openalex.org/W1866138264', 'https://openalex.org/W2100073316', 'https://openalex.org/W2108493868', 'https://openalex.org/W2119102073', 'https://openalex.org/W2170352271', 'https://openalex.org/W2517444733', 'https://openalex.org/W2592509339', 'https://openalex.org/W2778132151', 'https://openalex.org/W2792383391', 'https://openalex.org/W2804521147', 'https://openalex.org/W2805536053', 'https://openalex.org/W2902895311', 'https://openalex.org/W2933743550', 'https://openalex.org/W2971064972', 'https://openalex.org/W2991491278', 'https://openalex.org/W3025750765', 'https://openalex.org/W3034063691', 'https://openalex.org/W3087412549', 'https://openalex.org/W3092060047', 'https://openalex.org/W3173818251', 'https://openalex.org/W3179556584', 'https://openalex.org/W3182115458'], 'related_works': ['https://openalex.org/W4319311304', 'https://openalex.org/W4318478878', 'https://openalex.org/W3182709878', 'https://openalex.org/W2910696677', 'https://openalex.org/W2806306665', 'https://openalex.org/W2793900558', 'https://openalex.org/W2565914894', 'https://openalex.org/W2090699703', 'https://openalex.org/W1967986271', 'https://openalex.org/W1458161714'], 'abstract_inverted_index': {'Background': [0], 'The': [1, 114, 146, 179], 'efficacy': [2, 28], 'and': [3, 37, 79, 88, 128, 140, 161, 173, 189, 197, 208], 'safety': [4], 'of': [5, 29, 39, 117, 134, 138, 143, 149, 167, 171, 176, 181, 195, 200, 217], 'lacosamide': [6], '(LCM)': [7], 'monotherapy': [8, 42, 55, 93, 106, 122, 155, 188, 191, 213], 'in': [9, 46, 56, 109], 'Chinese': [10], 'pediatric': [11, 47, 101, 112, 118, 150], 'patients': [12, 51, 119, 151], 'with': [13, 94, 123, 156, 184], 'epilepsy': [14, 44], 'have': [15], 'not': [16], 'been': [17], 'established.': [18], 'Therefore,': [19], 'this': [20], 'real-world': [21], 'retrospective': [22], 'study': [23], 'aimed': [24], 'to': [25, 98, 105, 154, 186], 'assess': [26], 'the': [27, 34, 73, 215], '12': [30, 89, 129, 162], 'months': [31, 76, 130, 163], 'after': [32], 'achievement': [33], 'maximal': [35], 'dose': [36], 'tolerability': [38], 'LCM': [40, 54, 95, 124, 157, 187, 204], 'as': [41, 67, 212], 'for': [43, 72, 85, 214], 'treatment': [45, 210, 216], 'patients.': [48, 113], 'Methods': [49], 'Pediatric': [50], 'were': [52, 131, 164], 'administered': [53, 97], 'two': [57], 'ways:': [58], 'primary': [59, 121, 190], 'or': [60], 'conversion': [61, 104, 153, 185], 'monotherapy.': [62], 'Seizure': [63], 'frequency': [64], 'was': [65, 96, 107, 192], 'recorded': [66], 'an': [68, 206], 'average': [69], 'per': [70], 'month': [71], 'preceding': [74], 'three': [75], 'at': [77, 81, 125, 158], 'baseline': [78], 'then': [80], 'each': [82], 'follow-up': [83], 'period': [84], 'three,': [86, 126, 159], 'six,': [87, 127, 160], 'months.': [90], 'Results': [91], 'Primary': [92], '37': [99], '(33.0%)': [100], 'patients,': [102], 'whereas': [103], 'achieved': [108], '75': [110], '(67.0%)': [111], 'responder': [115, 147], 'rates': [116, 148], 'receiving': [120, 152], '75.7%': [132], '(28': [133], '37),': [135, 201], '67.6%': [136], '(23': [137], '34),': [139], '58.6%': [141], '(17': [142], '29),': [144], 'respectively.': [145, 178, 202], '80.0%': [165], '(60': [166], '75),': [168], '74.3%': [169], '(55': [170], '74),': [172], '68.1%': [174], '(49': [175], '72),': [177], 'incidence': [180], 'adverse': [182], 'reactions': [183], '32.0%': [193], '(24': [194], '75)': [196], '40.5%': [198], '(15': [199], 'Conclusion': [203], 'is': [205], 'effective': [207], 'well-tolerated': [209], 'option': [211], 'epilepsy.': [218]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4319311304', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}], 'updated_date': '2024-09-18T00:19:02.221686', 'created_date': '2023-02-08'}