Abstract: The subject of oxidative stress is introduced. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) which are endogenously produced highly reactive free radical species as by-products of cellular metabolic activities. Beneficial effects of ROS an RNS include protection against pathogens, wound healing and tissue repair. Excessive production of ROS and RON, however, results in an imbalance known as oxidative stress. This imbalance is naturally counteracted by antioxidants. When oxidative stress levels exceed the body's ability to overcome this imbalance, however, early aging and disease onset ensue. Exogenous and endogenous parameters responsible for oxidative stress are discussed.
Publication Year: 2022
Publication Date: 2022-10-29
Language: en
Type: book-chapter
Indexed In: ['crossref']
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