Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4232858418', 'doi': 'https://doi.org/10.1161/circulationaha.117.030509', 'title': 'Embolic Stroke', 'display_name': 'Embolic Stroke', 'publication_year': 2017, 'publication_date': '2017-12-19', 'ids': {'openalex': 'https://openalex.org/W4232858418', 'doi': 'https://doi.org/10.1161/circulationaha.117.030509', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29255121'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/circulationaha.117.030509', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.030509', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.030509', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076026606', 'display_name': 'George Ntaios', 'orcid': 'https://orcid.org/0000-0002-0629-9248'}, 'institutions': [{'id': 'https://openalex.org/I4210107217', 'display_name': 'University Hospital of Larissa', 'ror': 'https://ror.org/01s5dt366', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107217']}, {'id': 'https://openalex.org/I145722265', 'display_name': 'University of Thessaly', 'ror': 'https://ror.org/04v4g9h31', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I145722265']}], 'countries': ['GR'], 'is_corresponding': True, 'raw_author_name': 'George Ntaios', 'raw_affiliation_strings': ['Department of Medicine, Larissa University Hospital, University of Thessaly, Greece (G.N.)'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Larissa University Hospital, University of Thessaly, Greece (G.N.)', 'institution_ids': ['https://openalex.org/I4210107217', 'https://openalex.org/I145722265']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086609118', 'display_name': 'Robert G. Hart', 'orcid': 'https://orcid.org/0000-0002-3210-167X'}, 'institutions': [{'id': 'https://openalex.org/I2802834092', 'display_name': 'Population Health Research Institute', 'ror': 'https://ror.org/03kwaeq96', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802834092']}, {'id': 'https://openalex.org/I98251732', 'display_name': 'McMaster University', 'ror': 'https://ror.org/02fa3aq29', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I98251732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Robert G. Hart', 'raw_affiliation_strings': ['Department of Medicine (Neurology), Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (R.G.H.).'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine (Neurology), Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (R.G.H.).', 'institution_ids': ['https://openalex.org/I2802834092', 'https://openalex.org/I98251732']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5076026606'], 'corresponding_institution_ids': ['https://openalex.org/I4210107217', 'https://openalex.org/I145722265'], 'apc_list': None, 'apc_paid': None, 'fwci': 5.371, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 65, 'citation_normalized_percentile': {'value': 0.890929, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '136', 'issue': '25', 'first_page': '2403', 'last_page': '2405'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10227', 'display_name': 'Epidemiology and Management of Stroke', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10227', 'display_name': 'Epidemiology and Management of Stroke', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10285', 'display_name': 'Prevention and Treatment of Venous Thromboembolism', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2724', 'display_name': 'Internal Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10816', 'display_name': 'Diagnosis and Treatment of Carotid Artery Disease', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/stroke', 'display_name': 'Stroke (engine)', 'score': 0.6031092}, {'id': 'https://openalex.org/keywords/infarction-treatment', 'display_name': 'Infarction Treatment', 'score': 0.498734}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9506457}, {'id': 'https://openalex.org/C2780645631', 'wikidata': 'https://www.wikidata.org/wiki/Q671554', 'display_name': 'Stroke (engine)', 'level': 2, 'score': 0.6031092}, {'id': 'https://openalex.org/C2910003425', 'wikidata': 'https://www.wikidata.org/wiki/Q12202', 'display_name': 'Embolic stroke', 'level': 4, 'score': 0.44892263}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.420965}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34378308}, {'id': 'https://openalex.org/C3020199598', 'wikidata': 'https://www.wikidata.org/wiki/Q12202', 'display_name': 'Ischemic stroke', 'level': 3, 'score': 0.2424916}, {'id': 'https://openalex.org/C541997718', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemia', 'level': 2, 'score': 0.14160115}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D020766', 'descriptor_name': 'Intracranial Embolism', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D002545', 'descriptor_name': 'Brain Ischemia', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020766', 'descriptor_name': 'Intracranial Embolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020766', 'descriptor_name': 'Intracranial Embolism', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D020766', 'descriptor_name': 'Intracranial Embolism', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/circulationaha.117.030509', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.030509', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29255121', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/circulationaha.117.030509', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.030509', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 4, 'referenced_works': ['https://openalex.org/W2116427214', 'https://openalex.org/W2165963692', 'https://openalex.org/W2475974359', 'https://openalex.org/W2944352279'], 'related_works': ['https://openalex.org/W3183948672', 'https://openalex.org/W3173606202', 'https://openalex.org/W3168361680', 'https://openalex.org/W3110381201', 'https://openalex.org/W2948807893', 'https://openalex.org/W2899084033', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2502103319', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'HomeCirculationVol.': [0], '136,': [1, 3447], 'No.': [2], '25Embolic': [3], 'Stroke': [4, 22, 1314, 1325, 1554, 1585, 1606, 1643, 1770, 2025, 2086, 2158, 2265, 2316, 2615, 2649, 2726, 2862, 2871, 2970, 3126, 3130, 3182, 3245, 3297, 3469], 'Free': [5], 'AccessArticle': [6, 20], 'CommentaryPDF/EPUBAboutView': [7], 'PDFView': [8], 'EPUBSections': [9], 'ToolsAdd': [10], 'to': [11, 94, 152, 228, 435, 442, 564, 664, 670, 802, 895, 908, 915, 995, 1011, 1057, 1140, 1162, 1177, 1183, 1251, 1621], 'favoritesDownload': [12], 'citationsTrack': [13], 'citationsPermissions': [14], 'ShareShare': [15], 'onFacebookTwitterLinked': [16], 'InMendeleyReddit': [17], 'Jump': [18], 'toFree': [19], 'CommentaryPDF/EPUBEmbolic': [21], 'George': [23, 31, 1372], 'Ntaios,': [24, 1373], 'MD': [25, 30], 'and': [26, 45, 144, 183, 189, 209, 212, 215, 267, 319, 343, 355, 361, 363, 377, 407, 419, 433, 452, 456, 541, 555, 574, 631, 650, 689, 718, 809, 850, 868, 871, 883, 919, 956, 965, 1019, 1048, 1156, 1179, 1283, 1290, 1315, 1329, 1590, 1634, 1673, 1678, 1723, 1735, 1771, 1807, 1828, 1856, 1881, 1916, 1921, 1932, 1962, 1971, 1977, 2006, 2026, 2068, 2083, 2135, 2160, 2194, 2200, 2209, 2223, 2260, 2269, 2302, 2308, 2321, 2343, 2349, 2355, 2376, 2413, 2426, 2478, 2520, 2575, 2593, 2612, 2638, 2674, 2684, 2715, 2722, 2790, 2798, 2845, 2872, 2906, 2939, 2946, 2957, 3006, 3026, 3032, 3045, 3063, 3068, 3103, 3131, 3171, 3232, 3237, 3249, 3282, 3287, 3314, 3366, 3372, 3397, 3423], 'Robert': [27, 46], 'G.': [28, 47, 49], 'Hart,': [29], 'NtaiosGeorge': [32], 'Ntaios': [33, 1260, 1510, 1632, 1674, 1721, 1917, 1963, 1990, 2097, 2195, 2219, 2256, 2303, 2389, 2448, 2543, 2675, 2695, 2791, 2821, 2882, 2966, 3041, 3087, 3141, 3312, 3344], 'Department': [34, 51, 1375], 'of': [35, 41, 52, 86, 107, 111, 116, 119, 164, 199, 236, 240, 278, 324, 365, 370, 395, 477, 486, 492, 601, 609, 679, 686, 693, 703, 705, 728, 745, 777, 781, 789, 793, 807, 816, 865, 925, 931, 968, 977, 981, 999, 1016, 1026, 1036, 1053, 1066, 1092, 1108, 1121, 1145, 1201, 1211, 1237, 1241, 1254, 1302, 1313, 1317, 1326, 1337, 1358, 1362, 1376, 1382, 1385, 1428, 1544, 1548, 1579, 1592, 1607, 1644, 1654, 1680, 1683, 1686, 1733, 1742, 1746, 1769, 1813, 1826, 1923, 1934, 1938, 1980, 2015, 2024, 2078, 2167, 2205, 2232, 2266, 2317, 2382, 2418, 2423, 2429, 2439, 2485, 2492, 2497, 2530, 2585, 2590, 2606, 2610, 2619, 2644, 2727, 2759, 2806, 2811, 2863, 2870, 2912, 2919, 2971, 2975, 2979, 3012, 3070, 3076, 3108, 3114, 3129, 3183, 3239, 3246, 3289, 3298, 3302, 3325, 3335, 3374, 3380, 3402, 3435], 'Medicine,': [36, 1377, 1383, 1655, 1940, 2211, 2813, 2962, 3033, 3436], 'Larissa': [37, 1378], 'University': [38, 40, 1379, 1384], 'Hospital,': [39, 1380], 'Thessaly,': [42, 1386], 'Greece': [43], '(G.N.)': [44], 'HartRobert': [48], 'Hart': [50, 1286, 1405, 1444, 1667, 2716, 3172, 3233], 'Medicine': [53], '(Neurology),': [54], 'Population': [55], 'Health': [56], 'Research': [57], 'Institute,': [58], 'McMaster': [59], 'University,': [60], 'Hamilton,': [61], 'Ontario,': [62], 'Canada': [63], '(R.G.H.).': [64], 'Originally': [65, 3460], 'published19': [66], 'Dec': [67], '2017https://doi.org/10.1161/CIRCULATIONAHA.117.030509Circulation.': [68], '2017;136:2403–2405The': [69], 'term': [70, 562, 1052, 1065, 1089], '“embolic”': [71], 'was': [72], 'first': [73], 'suggested': [74], 'in': [75, 375, 381, 399, 414, 449, 531, 570, 677, 691, 713, 985, 1069, 1085, 1111, 1193, 1247, 1310, 1320, 1351, 1539, 1583, 1602, 1820, 1868, 1926, 2018, 2143, 2229, 2314, 2489, 2526, 2652, 2680, 2724, 2730, 2746, 2803, 2952, 3016, 3030, 3058, 3119, 3178, 3243, 3293, 3328, 3377, 3407], '1854': [76], 'by': [77, 90, 1152, 2155, 2600], 'Virchow1': [78], 'when': [79, 1173], 'he': [80], 'described': [81], 'a': [82, 123, 133, 429, 474, 498, 587, 671, 714, 798, 804, 856, 860, 876, 884, 997, 1070, 1202, 1227, 1235, 1291, 1434, 1739, 1874, 1886, 1892], 'patient': [83, 715, 861, 877, 1071, 1165, 1185], 'with': [84, 136, 283, 332, 469, 535, 716, 862, 878, 927, 941, 950, 1003, 1023, 1033, 1072, 1118, 1257, 1541, 1604, 1822, 2020, 2075, 2080, 2145, 2420, 2587, 2682, 3060, 3121, 3330], 'occlusion': [85, 1866], 'the': [87, 97, 105, 117, 137, 200, 206, 210, 234, 238, 310, 368, 501, 504, 509, 553, 561, 571, 578, 583, 680, 684, 694, 701, 709, 726, 743, 754, 760, 778, 786, 790, 847, 897, 923, 932, 978, 1000, 1013, 1024, 1034, 1037, 1046, 1062, 1079, 1086, 1101, 1105, 1133, 1142, 1189, 1194, 1199, 1209, 1242, 1299, 1303, 1331, 1338, 1359, 1363, 1431, 1549, 1588, 1593, 1681, 1731, 1743, 1981, 2013, 2156, 2161, 2235, 2527, 2583, 2601, 2607, 2613, 2648, 2731, 2752, 2913, 2917, 2976, 3112, 3115, 3303, 3323, 3408], 'brain': [88], 'arteries': [89], 'clots': [91], 'that': [92, 104, 224, 567, 666, 674, 946, 1160, 1169], 'appeared': [93], 'arise': [95], 'from': [96, 171, 196, 243, 258, 274, 329, 350, 482, 552, 1045, 1275, 1293], 'heart.': [98], 'All': [99], 'currently': [100], 'available': [101, 1368], 'evidence': [102], 'suggests': [103], 'majority': [106, 369, 491, 744, 924], 'ischemic': [108, 120, 128, 165, 454, 2146, 2150, 2356, 3331], 'strokes': [109, 1427, 1543], 'are': [110, 225, 373, 424, 460, 495, 516, 568, 612, 633, 652, 748, 1150, 1175, 1249, 1354], 'an': [112, 127, 157, 241, 382, 794, 901, 982, 1167], 'embolic': [113, 610, 687, 706, 772, 795, 898, 928, 951, 983, 1017, 1029, 1119, 1258, 1542, 1684, 2203, 2230, 2421, 2487, 2490, 2531, 2588, 2804, 3378], 'nature.2The': [114], 'identification': [115, 788, 930], 'cause': [118, 685, 792, 858, 934, 980], 'stroke': [121, 129, 611, 688, 707, 729, 796, 899, 906, 913, 942, 952, 984, 1018, 1055, 1068, 1091, 1120, 1205, 1537, 1685, 1734, 2147, 2204, 2231, 2422, 2491, 2532, 2589, 2605, 2683, 2745, 2805, 2956, 3056, 3379], 'is': [122, 130, 151, 560, 660, 732, 759, 797, 935, 992, 1009, 1043, 1100, 1127, 1367], '2-step': [124], 'process.': [125], 'Initially,': [126], 'classified': [131, 613, 769], 'on': [132, 156, 518, 900, 1208, 1330, 1749, 1873, 2755, 2851, 3021], 'pathophysiologic': [134, 140], 'basis,': [135], '2': [138], 'main': [139, 1143], 'mechanisms': [141], 'being': [142], 'embolism': [143, 168, 193, 255, 271, 322, 347, 808], 'small-vessel': [145], 'disease': [146, 326, 2354], '(Figure).': [147], 'The': [148, 1239, 1651, 2434, 2642, 2866, 3124], 'next': [149], 'step': [150], 'classify': [153, 896], 'it': [154, 411, 667, 890, 991, 1008, 1022], 'further': [155, 1020], 'etiologic': [158, 902], 'basis.Download': [159], 'figureDownload': [160], 'PowerPointFigure.': [161], 'Pathophysiologic': [162], 'classification': [163], 'stroke.': [166], 'Nonthrombosis-mediated': [167], 'may': [169, 194, 256, 272, 327, 348, 393, 403, 412, 480, 526, 550, 738, 823, 834, 1096], 'originate': [170, 195, 257, 273, 328, 349, 481, 551], 'septic': [172], 'vegetations,': [173, 416], 'valvular': [174, 325, 417], 'calcified': [175, 340, 542], 'fragments,': [176], 'cardiac': [177, 346, 357, 384, 450, 493, 520, 628], 'tumors': [178], '(eg,': [179, 712, 859, 953], 'myxoma,': [180, 351], 'papillary': [181, 352], 'fibroelastoma,': [182, 353], 'sarcoma),': [184], 'fibrocartilaginous': [185, 359], 'material,': [186, 360, 397, 409], 'air,': [187], 'fat,': [188], 'others.2': [190, 268, 320, 344], 'Atherosclerotic': [191], 'arteriogenic': [192, 254], 'any': [197, 1122], 'part': [198], 'brain-supplying': [201], 'arterial': [202, 222, 251, 488, 580], 'tree,': [203], 'such': [204, 232, 538, 621, 640], 'as': [205, 233, 247, 249, 410, 539, 614, 622, 635, 641, 654, 683, 725, 770, 1226, 1234, 1269, 1298], 'aortic': [207, 337, 341, 645, 954, 962], 'arch': [208, 955], 'intracranial': [211], 'extracranial': [213], 'carotid': [214, 624, 873, 909, 957, 1823, 3013], 'vertebrobasilar': [216], 'arteries,': [217, 237, 261], 'but': [218], 'mainly': [219], 'involves': [220], 'those': [221, 1357], 'segments': [223], 'more': [226, 462], 'prone': [227], 'develop': [229], 'atherosclerotic': [230, 431, 625], 'plaques,': [231, 626], 'bifurcation': [235], 'origin': [239], 'artery': [242, 2959], 'its': [244], 'parent': [245], 'vessel,': [246], 'well': [248], 'tortuous': [250], 'segments.': [252], 'Nonatherosclerotic': [253], 'dissected': [259], 'cervical': [260], 'Moya': [262, 263], 'disease,': [264, 339, 964, 1871], 'Takayasu': [265], 'arteritis,': [266], 'Cardiac': [269, 321, 1639], 'chamber': [270, 499], 'thrombus': [275], 'formed': [276, 380, 427, 484, 496, 517, 569], 'because': [277, 323, 485, 730], 'left': [279, 502, 505, 510, 959], 'ventricular': [280, 960], '(LV)': [281], 'dysfunction': [282], 'preserved': [284], 'or': [285, 317, 388, 508, 533, 595, 616, 648, 844, 875, 911, 1267, 1271, 1361, 2148, 3053], 'reduced': [286], 'ejection': [287], 'fraction,': [288], 'LV': [289, 296], 'regional': [290], 'wall': [291], 'abnormalities': [292], 'after': [293, 2202, 2860], 'myocardial': [294], 'infarction,': [295], 'noncompaction,': [297], 'atrial': [298, 303, 311, 313, 470, 506, 592, 2432, 2747, 2795, 2801, 2954, 3375], 'septal': [299, 593], 'aneurysm,': [300], 'Chiari': [301], 'network,': [302], 'asystole,': [304], 'sick-sinus': [305], 'syndrome,': [306], 'blood': [307], 'stasis': [308], 'into': [309, 577], 'appendage,': [312, 507], 'fibrillation': [314, 471, 2748, 2802, 2955, 3376], '(AF),': [315], 'flutter': [316], 'tachycardias,': [318], 'myxomatous': [330], 'valvulopathy': [331], 'prolapse,': [333, 644], 'mitral': [334, 642], 'annular': [335], 'calcification,': [336, 649], 'valve': [338, 643, 646, 963], 'valves,': [342, 629], 'Nonthrombotic': [345], 'sarcoma': [354], 'other': [356, 420, 513, 812, 842], 'tumors,': [358], 'others.2Pathophysiology': [362], 'Etiology': [364], 'Embolic': [366, 605, 782, 1324, 1426, 1605, 1642, 1765, 2264, 2315, 2720, 2725, 2861, 2969, 3181, 3244, 3291, 3296], 'StrokeIn': [367], 'patients,': [371, 478, 514, 889, 1007, 1113], 'emboli': [372, 392, 440, 447, 479, 566], 'thrombotic': [374, 406, 530], 'nature': [376, 532], 'can': [378, 973, 1223], 'be': [379, 443, 527, 740, 767, 824, 893, 948, 976, 1141, 1224], 'artery,': [383], 'chamber,': [385], 'heart': [386, 554, 1737, 3061], 'valve,': [387], 'vein.': [389], 'Less': [390], 'frequently,': [391], 'consist': [394], 'nonthrombotic': [396, 408, 536, 548], 'whereas': [398, 638], 'certain': [400], 'cases': [401, 765, 833], 'they': [402], 'contain': [404], 'both': [405], 'occur': [413], 'infected': [415], 'calcifications,': [418], 'pathologies': [421, 489, 620, 682, 711, 945], '(Figure).2Arteriogenic': [422], 'thrombi': [423, 483, 494, 515, 525], 'most': [425, 720, 989, 1148, 1255], 'frequently': [426], 'at': [428, 1369, 2647], 'ruptured': [430], 'plaque': [432, 3014], 'embolize': [434, 556, 575], 'cerebral': [436, 579], 'arteries.': [437], 'These': [438], 'platelet-rich': [439], 'tend': [441], 'smaller': [444, 475], 'than': [445, 464, 757, 1032, 1216, 1233], 'fibrin-rich': [446], 'originating': [448], 'chambers,': [451], 'transient': [453, 2149], 'attacks': [455], 'small': [457], 'cortical': [458], 'infarcts': [459, 467], 'relatively': [461], 'common': [463], 'large,': [465], 'territorial': [466], 'associated': [468, 818, 949, 1736], '(AF).': [472], 'In': [473, 512, 544, 887, 988, 1005, 1076, 1187, 1219], 'proportion': [476], 'nonatherosclerotic': [487], '(Figure).2The': [490, 599], 'within': [497], '(ie,': [500, 904, 1213], 'ventricle,': [503], 'atrium).': [511], 'pathological': [519], 'valves.2': [521], 'As': [522], 'mentioned,': [523], 'these': [524, 764, 888, 986, 1006, 1146, 1181], 'either': [528], 'purely': [529], 'mixed': [534], 'material': [537, 549], 'vegetations': [540], 'material.': [543], 'some': [545, 750], 'infrequent': [546], 'cases,': [547, 746, 990], 'distally': [557, 576], '(Figure).2“Paradoxical': [558], 'embolism”': [559], 'used': [563], 'describe': [565], 'venous': [572, 881, 917], 'vasculature': [573], 'vasculature,': [581], 'bypassing': [582], 'pulmonary': [584, 596], 'circulation': [585], 'through': [586, 1262], 'patent': [588, 2594], 'foramen': [589, 2595], 'ovale': [590], '(PFO),': [591], 'defects,': [594], 'arteriovenous': [597], 'fistulas': [598], 'Concept': [600], 'Major-': [602], 'Versus': [603, 1308, 3241], 'Minor-Risk': [604], 'SourcesFrequently,': [606], 'potential': [607, 805, 813, 1028, 1059, 1074, 1814, 2486], 'sources': [608, 1030, 2488], 'major': [615, 636, 734], 'minor': [617, 655], 'risk.': [618, 819], 'Certain': [619], 'stenotic': [623], 'mechanical': [627], 'AF,': [630, 758], 'others': [632, 639], 'considered': [634, 653, 733], 'risk,': [637], 'stenosis': [647], 'PFO': [651, 3405, 3427], 'risk.2': [656], 'Although': [657, 736], 'this': [658, 737, 822, 1077, 1099, 1220, 1352], 'approach': [659, 1168], 'valid,': [661], 'we': [662, 974], 'need': [663], 'realize': [665], 'actually': [668, 1115], 'leads': [669], 'self-fulfilling': [672], 'prophecy': [673], 'inevitably': [675], 'results': [676, 1240], 'overestimation': [678], 'major-risk': [681], 'simultaneously': [690], 'underestimation': [692], 'minor-risk': [695], 'pathologies.': [696], 'This': [697, 1137], 'systematic': [698], 'error': [699], 'skews': [700], 'distribution': [702], 'causes': [704, 814], 'toward': [708, 855, 1061], 'high-risk': [710], 'AF': [717, 724, 731], 'PFO,': [719, 755], 'clinicians': [721], 'would': [722, 766, 891], 'consider': [723], 'etiology': [727, 1002, 1123], 'risk).': [735], 'indeed': [739, 892], 'true': [741], 'for': [742, 752, 775, 785, 830, 922, 1104, 1124, 1296, 1345, 1433, 1535, 1729, 1817, 1863, 2012, 2140, 2582, 2604, 2916, 3055, 3111, 3322, 3404, 3429], 'there': [747, 1126], 'still': [749, 1128], 'patients': [751, 837, 845, 926, 940, 1117, 1256, 1540, 1603, 1821, 2144, 2419, 2586, 2681, 3059, 3329], 'whom': [753], 'rather': [756, 825, 1031, 1215, 1232], 'actual': [761, 979], 'cause.': [762], 'However,': [763], 'erroneously': [768], 'AF-associated': [771], 'stroke.The': [773], 'Quest': [774], 'Identification': [776, 2417, 3401], 'Underlying': [779], 'Cause': [780], 'StrokeThe': [783], 'prerequisite': [784], 'reliable': [787], 'underlying': [791, 933, 1001], 'thorough': [799], 'diagnostic': [800, 851, 1051, 1064], 'evaluation': [801, 2529], 'identify': [803], 'source': [806, 1094, 2425, 2592], 'exclude': [810], 'all': [811, 1027], 'regardless': [815], 'their': [817], 'At': [820], 'times': [821], 'straightforward,': [826], 'leaving': [827], 'little': [828], 'room': [829], 'doubt.': [831], 'Such': [832], 'include': [835, 1116], 'young': [836], 'who': [838], 'usually': [839], 'have': [840, 943], 'no': [841, 1129], 'comorbidities': [843], 'where': [846], 'overall': [848], 'clinical': [849, 1436, 2153, 2598], 'assessment': [852, 3011], 'points': [853], 'overwhelmingly': [854], 'specific': [857, 1038], 'sudden': [863], 'onset': [864], 'unilateral': [866], 'head': [867], 'neck': [869], 'pain': [870], 'ipsilateral': [872], 'dissection,': [874], 'recent': [879], 'deep': [880, 916], 'thrombosis': [882, 918], 'large': [885, 1243, 2958], 'PFO.': [886], 'valid': [894], 'basis': [903, 1103, 1210], '“embolic': [905, 912, 1054, 1067, 1090], 'due': [907, 914, 1056], 'dissection”': [910], 'PFO”': [920], 'respectively).However,': [921], 'stroke,': [929, 2961, 3332], 'less': [936], 'straightforward.': [937], 'Most': [938], 'elderly': [939], 'multiple': [944], 'could': [947, 1138], 'atherosclerosis,': [958, 1824, 2686], 'dysfunction,': [961], 'short': [966], 'episodes': [967], 'supraventricular': [969], 'tachycardia).': [970], 'How': [971], 'confident': [972], 'really': [975], 'patients?': [987], 'not': [993, 1355], 'possible': [994], 'make': [996], 'diagnosis': [998, 1015, 1236], 'certainty.': [1004], 'preferable': [1010], 'offer': [1012], 'pathophysiological': [1014], 'enrich': [1021], 'description': [1025], 'presumption': [1035], 'etiology.': [1039, 1218], 'A': [1040, 1860, 1974, 2152, 2358, 2597], 'paradigm': [1041], 'shift': [1042], 'warranted': [1044], 'presumptive': [1047], 'endogenously': [1049], 'uncertain': [1050], '[presumed': [1058], 'cause]”': [1060], 'inclusive': [1063], '[all': [1073], 'causes].”': [1075], 'context,': [1078, 1221], 'words': [1080], '“of': [1081], 'undetermined': [1082, 1093, 1429, 1545, 1687, 2206, 2233, 2424, 2493, 2591, 2807, 3381], 'source”': [1083], 'included': [1084], 'recently': [1087], 'introduced': [1088], '(ESUS)”': [1095], 'seem': [1097], 'redundant.Actually,': [1098], 'conceptual': [1102], 'ongoing': [1106, 1195], 'trials': [1107, 1149, 1197], 'antithrombotic': [1109, 1135], 'management': [1110, 1253, 1732, 2584], 'ESUS': [1112, 1196, 1222, 1244, 1305, 1576], 'which': [1114, 1125], 'clear': [1130], 'answer': [1131], 'about': [1132], 'optimal': [1134], 'treatment.3,4': [1136], 'prove': [1139], 'strength': [1144], 'trials:': [1147], 'limited': [1151], 'narrow': [1153], 'eligibility': [1154], 'criteria': [1155, 1192], 'consequently': [1157], 'yield': [1158], 'conclusions': [1159, 1182], 'apply': [1161, 1180], 'highly': [1163], 'selected': [1164, 1207], 'populations,': [1166], 'later': [1170], 'raises': [1171], 'concerns': [1172], 'physicians': [1174], 'tempted': [1176], 'extrapolate': [1178], 'broader': [1184], 'populations.': [1186], 'contrast,': [1188], 'broad': [1190], 'selection': [1191], 'allow': [1198], 'inclusion': [1200], 'widely': [1203], 'representative': [1204], 'population': [1206], 'pathophysiology': [1212], 'embolism)': [1214], 'best-guess': [1217], 'seen': [1225], 'positive,': [1228], 'inclusive,': [1229], 'pathophysiology-based': [1230], 'definition': [1231], 'exclusion.': [1238], 'trials,': [1245, 3073], 'anticipated': [1246], '2018,': [1248], 'likely': [1250], 'inform': [1252], 'stroke.3,4DisclosuresDr': [1259], 'received': [1261, 1287], 'his': [1263], 'institution': [1264], 'research': [1265, 1288], 'support': [1266, 1289], 'fees': [1268], 'speaker': [1270], 'advisory': [1272], 'board': [1273], 'member': [1274], 'Amgen,': [1276], 'Bayer,': [1277], 'BMS/Pfizer,': [1278], 'Boehringer-Ingelheim,': [1279], 'Elpen,': [1280], 'Galenica,': [1281], 'Sanofi,': [1282], 'Winmedica.': [1284], 'Dr': [1285], 'stipend': [1292], 'Bayer': [1294], 'AG': [1295], 'serving': [1297], 'co-principal': [1300], 'investigator': [1301], 'NAVIGATE': [1304], 'trial': [1306, 1342], '(Rivaroxaban': [1307], 'Aspirin': [1309, 3242], 'Secondary': [1311], 'Prevention': [1312, 1316, 1586], 'Systemic': [1318], 'Embolism': [1319], 'Patients': [1321, 2019, 3120, 3179, 3294], 'With': [1322, 3180, 3295], 'Recent': [1323], 'Undetermined': [1327, 1608, 1645, 2267, 2318, 2728, 2864, 2972, 3184, 3247, 3299], 'Source)': [1328], 'Steering': [1332], '&': [1333, 2363], 'Event': [1334], 'Adjudication': [1335], 'Committees': [1336], 'COMPASS/COMPASS': [1339], 'MIND': [1340], '(MRI)': [1341], '(Cardiovascular': [1343], 'Outcomes': [1344, 2723], 'People': [1346], 'Using': [1347], 'Anticoagulation': [1348], 'Strategy).FootnotesThe': [1349], 'opinions': [1350], 'article': [1353], 'necessarily': [1356], 'editors': [1360], 'American': [1364, 1652, 1982, 2977, 3304, 3455], 'Heart': [1365, 1752, 1983, 2239, 3305, 3456], 'Association.Circulation': [1366], 'http://circ.ahajournals.org.Correspondence': [1370], 'to:': [1371], 'MD,': [1374], 'School': [1381], 'Biopolis': [1387], '41110,': [1388], 'Larissa,': [1389], 'Greece.': [1390], 'E-mail': [1391], '[email': [1392], 'protected]References1.': [1393], 'Virchow': [1394], 'R.': [1395], 'Handbuch': [1396], 'der': [1397], 'speciellen': [1398], 'Pathologie': [1399], 'und': [1400], 'Therapie.': [1401], 'Erlangen:': [1402], 'Enke;1854–1876.Google': [1403], 'Scholar2.': [1404], 'RG,': [1406, 1445], 'Diener': [1407, 1559, 1663], 'HC,': [1408, 1560], 'Coutts': [1409], 'SB,': [1410], 'Easton': [1411, 1561, 1665], 'JD,': [1412, 1562], 'Granger': [1413, 1563], 'CB,': [1414, 1564], 'O’Donnell': [1415, 1524], 'MJ,': [1416, 1525], 'Sacco': [1417, 1573, 1715], 'RL,': [1418], 'Connolly': [1419, 1532, 2713, 3169, 3230], 'SJ;': [1420], 'Cryptogenic': [1421, 3430], 'Stroke/ESUS': [1422], 'International': [1423, 2165, 2437, 3074, 3333], 'Working': [1424], 'Group.': [1425], 'source:': [1430, 1546, 2234], 'case': [1432], 'new': [1435, 2430, 2799], 'construct.Lancet': [1437], 'Neurol.': [1438], '2014;': [1439], '13:429–438.': [1440], 'doi:': [1441, 1616], '10.1016/S1474-4422(13)70310-7.CrossrefMedlineGoogle': [1442], 'Scholar3.': [1443], 'Sharma': [1446, 2701], 'M,': [1447, 1505, 1572, 1712, 1899, 2049, 2052, 2104, 2517, 2702, 2989, 2999, 3001, 3148, 3420], 'Mundl': [1448, 2709, 3161, 3206], 'H,': [1449, 1664, 1909, 1955, 2114, 2191, 2558, 2708, 2710, 2934, 2991, 3098, 3162, 3207, 3227], 'Shoamanesh': [1450], 'A,': [1451, 1467, 1489, 1503, 1519, 1523, 1796, 1804, 1913, 1995, 2043, 2045, 2124, 2130, 2340, 2400, 2404, 2465, 2469, 2546, 2556, 2775, 2779, 2832, 2836, 2893, 2897, 2996, 3269, 3273, 3353, 3357], 'Kasner': [1452, 1669, 2703], 'SE,': [1453], 'Berkowitz': [1454, 2711, 3163, 3196], 'SD,': [1455], 'Pare': [1456], 'G,': [1457, 1465, 1511, 1700, 1706, 1800, 1947, 1991, 2098, 2100, 2220, 2251, 2257, 2289, 2390, 2396, 2449, 2461, 2544, 2552, 2659, 2696, 2771, 2822, 2828, 2883, 2889, 3042, 3086, 3088, 3142, 3193, 3259, 3265, 3345, 3349], 'Kirsch': [1458], 'B,': [1459, 1631, 3195, 3215], 'Pogue': [1460], 'J,': [1461, 1477, 1527, 1666, 1843, 1853, 1911, 2037, 2039, 2041, 2054, 2056, 2063, 2509, 2511, 2629, 2633, 3160, 3203, 3225], 'Pater': [1462], 'C,': [1463, 1568, 1720, 1849, 1959, 2112, 2122, 2333, 2335, 2631, 3158], 'Peters': [1464], 'Davalos': [1466], 'Lang': [1468, 3153, 3200], 'W,': [1469, 1708, 2936, 2993, 3154, 3201, 3394], 'Wang': [1470, 1472, 2330, 2341, 2937], 'Y,': [1471, 1473, 1798, 2337, 3166], 'Cunha': [1474], 'L,': [1475, 1566, 1710, 1782, 1792, 2457, 2665, 2698, 3144], 'Eckstein': [1476], 'Tatlisumak': [1478], 'T,': [1479, 1841, 2065, 2118, 2635], 'Shamalov': [1480], 'N,': [1481, 1521, 1847, 1905, 2102, 2106, 2932, 3156, 3209], 'Mikulik': [1482], 'R,': [1483, 1507, 1513, 1668, 1704, 1716, 1718, 2061, 2331, 2455, 2700, 3199], 'Lavados': [1484, 3204], 'P,': [1485, 1497, 1901, 3150, 3205, 3213, 3217], 'Hankey': [1486], 'GJ,': [1487], 'Czlonkowska': [1488], 'Toni': [1490], 'D,': [1491, 1499, 1570, 1627, 1702, 1714, 1897, 1945, 1957, 1993, 2096, 2177, 2249, 2283, 2285, 2394, 2398, 2459, 2463, 2550, 2568, 2657, 2773, 2826, 2830, 2887, 2891, 3263, 3267, 3351], 'Ameriso': [1492], 'SF,': [1493], 'Gagliardi': [1494, 3198], 'RJ,': [1495], 'Amarenco': [1496, 3149, 3212], 'Bereczki': [1498], 'Uchiyama': [1500], 'S,': [1501, 1517, 1629, 1670, 2183, 2253, 2291, 2451, 2513, 2562, 2570, 2704, 2712, 3003, 3100, 3152, 3164, 3168, 3197], 'Lindgren': [1502], 'Endres': [1504, 3147], 'Brouns': [1506], 'Yoon': [1508], 'B-W,': [1509], 'Veltkamp': [1512, 2699], 'Muir': [1514], 'KW,': [1515], 'Ozturk': [1516, 3151], 'Arauz': [1518], 'Bornstein': [1520, 3155, 3208], 'Bryer': [1522], 'Weitz': [1526], 'Peacock': [1528], 'F,': [1529, 2058], 'Themeles': [1530], 'E,': [1531, 1903, 1907, 1953, 1997, 1999, 2001, 2047, 2108, 2185, 2187, 2293, 2295, 2402, 2406, 2408, 2467, 2471, 2473, 2507, 2548, 2554, 2667, 2706, 2777, 2781, 2783, 2834, 2838, 2840, 2895, 2899, 2901, 3092, 3094, 3096, 3146, 3211, 3221, 3271, 3275, 3277, 3355, 3359, 3361, 3392], 'SJ.': [1533], 'Rivaroxaban': [1534, 3240], 'secondary': [1536, 1584], 'prevention': [1538, 3057, 3324], 'Design': [1547, 1578], 'navigate': [1550], 'esus': [1551], 'randomized': [1552, 3071], 'trial.Eur': [1553], 'J.': [1555], '2016;': [1556], '1:146–154.CrossrefMedlineGoogle': [1557], 'Scholar4.': [1558], 'Cronin': [1565], 'Duffy': [1567], 'Cotton': [1569], 'Brueckmann': [1571], 'RL;': [1574], 'RE-SPECT': [1575], 'Investigators.': [1577], 'Randomized,': [1580], 'double-blind,': [1581], 'Evaluation': [1582], 'comparing': [1587], 'EfficaCy': [1589], 'safety': [1591], 'oral': [1594], 'Thrombin': [1595], 'inhibitor': [1596], 'dabigatran': [1597], 'etexilate': [1598], 'vs.': [1599], 'acetylsalicylic': [1600], 'acid': [1601], 'Source': [1609, 2268, 2729, 3248], '(RE-SPECT': [1610], 'ESUS).Int': [1611], 'J': [1612, 2067, 2637, 3005, 3425], 'Stroke.': [1613], '2015;': [1614], '10:1309–1312.': [1615], '10.1111/ijs.12630.MedlineGoogle': [1617], 'Scholar': [1618], 'Previous': [1619], 'Back': [1620], 'top': [1622], 'Next': [1623], 'FiguresReferencesRelatedDetailsCited': [1624], 'By': [1625], 'Sagris': [1626, 1896, 1944, 1992, 2095, 2176, 2282, 2656], 'Harrison': [1628], 'Buckley': [1630], 'G': [1633, 1636, 1675, 1722, 1915, 1918, 1961, 1964, 2196, 2304, 2676, 2792, 2967, 3047, 3102, 3313], 'Lip': [1635, 1699, 1960, 3046, 3101], '(2022)': [1637, 1676, 1726, 1763, 1810, 1859, 1884], 'Long-Term': [1638], 'Monitoring': [1640], 'After': [1641], 'Source:': [1646, 2865], 'Search': [1647], 'Longer,': [1648], 'Look': [1649], 'Harder,': [1650], 'Journal': [1653, 1768, 1825, 1937, 1979, 2023, 2166, 2381, 2438, 2496, 2618, 2758, 2810, 2869, 2974, 3075, 3128, 3301, 3334, 3434], '10.1016/j.amjmed.2022.04.030,': [1656], '135:9,': [1657], '(e311-e317),': [1658], 'Online': [1659, 1695, 1757, 1777, 1834, 1986, 2032, 2091, 2172, 2215, 2244, 2276, 2326, 2368, 2444, 2502, 2539, 2624, 2691, 2737, 2764, 2817, 2878, 2927, 2984, 3037, 3081, 3137, 3189, 3255, 3308, 3340, 3387, 3415, 3440], 'publication': [1660, 1696, 1758, 1778, 1835, 1987, 2033, 2092, 2173, 2216, 2245, 2277, 2327, 2369, 2445, 2503, 2540, 2625, 2692, 2738, 2765, 2818, 2879, 2928, 2985, 3038, 3082, 3138, 3190, 3256, 3309, 3341, 3388, 3416, 3441], 'date:': [1661, 1697, 1759, 1779, 1836, 1988, 2034, 2093, 2174, 2217, 2246, 2278, 2328, 2370, 2446, 2504, 2541, 2626, 2693, 2739, 2766, 2819, 2880, 2929, 2986, 3039, 3083, 3139, 3191, 3257, 3310, 3342, 3389, 3417, 3442], '1-Sep-2022.': [1662], 'Kamel': [1671], 'H': [1672, 2137, 2342, 2673, 3316], 'Review': [1677, 1931, 1976], 'update': [1679], 'concept': [1682], 'source,': [1688, 2207, 2237, 2494, 2533, 2808, 3382], 'Nature': [1689], 'Reviews': [1690], 'Neurology,': [1691, 2498, 2653, 2687, 3383], '10.1038/s41582-022-00663-4,': [1692], '18:8,': [1693], '(455-465),': [1694], '1-Aug-2022.': [1698], 'Lane': [1701], 'Lenarczyk': [1703], 'Boriani': [1705], 'Doehner': [1707], 'Benjamin': [1709], 'Fisher': [1711], 'Lowe': [1713], 'Schnabel': [1717], 'Watkins': [1719], 'Potpara': [1724], 'T': [1725], 'Integrated': [1727], 'care': [1728], 'optimizing': [1730], 'disease:': [1738], 'position': [1740], 'paper': [1741], 'European': [1744, 1751, 2238, 2495, 2809], 'Society': [1745, 2609], 'Cardiology': [1747, 2611], 'Council': [1748], 'Stroke,': [1750, 2022, 2168, 2273, 2440, 2734, 2924, 3077, 3186, 3252, 3336, 3431], 'Journal,': [1753, 2240], '10.1093/eurheartj/ehac245,': [1754], '43:26,': [1755], '(2442-2460),': [1756], '7-Jul-2022.': [1760], 'Ker': [1761], 'P': [1762, 1883, 2225, 2262, 2301, 2415, 2480, 2789, 2844, 2908, 3284, 3365, 3422], 'Cryptogenic,': [1764], 'Stroke—Looking': [1766], 'Backstage,': [1767], 'Cerebrovascular': [1772, 2027, 2873, 3132], 'Diseases,': [1773, 2028, 2874, 3133], '10.1016/j.jstrokecerebrovasdis.2022.106353,': [1774], '31:5,': [1775], '(106353),': [1776], '1-May-2022.': [1780], 'Yanchao': [1781], 'Sibin': [1783], 'Z,': [1784, 1790], 'Gareev': [1785], 'I,': [1786, 1851, 2181, 2281, 2572, 2661], 'Huan': [1787], 'X,': [1788, 1802, 1839, 1845], 'Junfei': [1789], 'Chunyang': [1791], 'Beylerli': [1793], 'O,': [1794], 'Sufianov': [1795], 'Chao': [1797], 'Yuyan': [1799], 'Xun': [1801], 'Ahmad': [1803], 'Peng': [1805], 'L': [1806], 'Guang': [1808], 'Y': [1809, 2938], 'Bioinformatics': [1811], 'analysis': [1812, 2484], 'therapeutic': [1815], 'targets': [1816], 'COVID-19': [1818, 1928], 'infection': [1819], 'Infection': [1827], 'Public': [1829], 'Health,': [1830], '10.1016/j.jiph.2022.03.004,': [1831], '15:4,': [1832], '(437-447),': [1833], '1-Apr-2022.': [1837], 'Zhang': [1838, 1852, 2940], 'Chan': [1840, 1958], 'Carbonella': [1842], 'Gong': [1844], 'Ahmed': [1846], 'Liu': [1848, 3165], 'Demandel': [1850], 'Pashankar': [1854], 'F': [1855], 'Mak': [1857], 'M': [1858, 2222, 3396, 3399], 'microfluidic-informatics': [1861], 'assay': [1862], 'quantitative': [1864], 'physical': [1865], 'measurement': [1867], 'sickle': [1869], 'cell': [1870], 'Lab': [1872], 'Chip,': [1875], '10.1039/D2LC00043A,': [1876], '22:6,': [1877], '(1126-1136)': [1878], 'Vysoký': [1879], 'R': [1880, 2717, 3173, 3234], 'Konečný': [1882], 'Rehabilitace': [1885], 'preskripce': [1887], 'pohybové': [1888], 'aktivity': [1889], 'u': [1890], 'kardiovaskulárních': [1891], 'vybraných': [1893], 'interních': [1894], 'onemocnění': [1895], 'Florentin': [1898], 'Tasoudis': [1900], 'Korompoki': [1902, 1952, 1998, 2107, 2186, 2292, 2405, 2470, 2666, 2705, 3093, 3220], 'Gatselis': [1904], 'Giamarellos-Bourboulis': [1906], 'Milionis': [1908, 1954, 2136, 2190, 2557, 2672, 2707, 3097, 3226, 3315], 'Douketis': [1910], 'Spyropoulos': [1912], 'Dalekos': [1914], '(2021)': [1919, 1965, 2009, 2197, 2263, 2346, 2379], 'Immunomodulation': [1920], 'Reduction': [1922], 'Thromboembolic': [1924, 1972], 'Risk': [1925, 2077, 3109, 3118], 'Hospitalized': [1927], 'Patients:': [1929], 'Systematic': [1930, 1975, 3066], 'Meta-Analysis': [1933], 'Randomized': [1935], 'Trials,': [1936], 'Clinical': [1939, 2534], '10.3390/jcm10225366,': [1941], '10:22,': [1942, 1985], '(5366)': [1943], 'Georgiopoulos': [1946, 2099, 2658, 3085], 'Pateras': [1948, 2662], 'K,': [1949, 1951, 2110, 2116, 2126, 2128, 2132, 2179, 2189, 2255, 2287, 2297, 2299, 2392, 2410, 2453, 2475, 2560, 2564, 2566, 2663, 2669, 2671, 2769, 2785, 2787, 2824, 2842, 2885, 2903, 3090, 3219, 3229, 3261, 3279, 3347, 3363], 'Perlepe': [1950, 2178, 2254, 2286, 2391, 2452, 2768, 2823, 2884, 3260, 3346], 'Tsiachris': [1956], 'Atrial': [1966, 2073, 2081, 2306, 2858, 2922], 'High‐Rate': [1967], 'Episode': [1968], 'Duration': [1969], 'Thresholds': [1970], 'Risk:': [1973], 'Meta‐Analysis,': [1978], 'Association,': [1984, 3306, 3457], '16-Nov-2021.': [1989], 'Kallipolitis': [1994], 'Karagkiozi': [1996, 2401, 2466, 2776, 2833, 2894, 3270, 3354], 'Manios': [2000, 2184, 2294, 2407, 2472, 2782, 2839, 2900, 3091, 3276, 3360], 'Plagianakos': [2002], 'V,': [2003, 2120, 2515, 3223], 'Vemmos': [2004, 2131, 2192, 2258, 2298, 2411, 2476, 2573, 2670, 2786, 2846, 2904, 3043, 3104, 3228, 3280, 3367], 'K': [2005, 2193, 2259, 2412, 2477, 2574, 2577, 2847, 2905, 3044, 3105, 3281, 3368], 'Maglogiannis': [2007], 'I': [2008], 'Machine-Learning-Derived': [2010], 'Model': [2011], 'Stratification': [2014], 'Cardiovascular': [2016, 3117], 'risk': [2017, 2348, 2428], 'Ischemic': [2021, 2744, 3122], '10.1016/j.jstrokecerebrovasdis.2021.106018,': [2029], '30:10,': [2030], '(106018),': [2031], '1-Oct-2021.': [2035, 2094], 'Pagola': [2036, 2628, 2630, 3159], 'Juega': [2038, 2632], 'Francisco-Pascual': [2040], 'Bustamante': [2042], 'Penalba': [2044], 'Pala': [2046], 'Rodriguez': [2048], 'De': [2050], 'Lera-Alfonso': [2051], 'Arenillas': [2053], 'Cabezas': [2055], 'Moniche': [2057], 'de': [2059, 2997], 'Torres': [2060], 'Montaner': [2062], 'González-Alujas': [2064, 2634], 'Alvarez-Sabin': [2066, 2636], 'Molina': [2069, 2639, 3157], 'C': [2070, 2640, 2742], '(2020)': [2071, 2138, 2226, 2305, 2416, 2481, 2523, 2578, 2641, 2677, 2718, 2743, 2793, 2848, 2942, 2968, 3009], 'Predicting': [2072], 'Fibrillation': [2074, 2859], 'High': [2076], 'Embolization': [2079], 'Strain': [2082], 'NT-proBNP,': [2084], 'Translational': [2085], 'Research,': [2087], '10.1007/s12975-020-00873-2,': [2088], '12:5,': [2089], '(735-741),': [2090], 'Kakaletsis': [2101], 'Elisaf': [2103], 'Katsiki': [2105], 'Kypreos': [2109], 'Boutari': [2111], 'Bilianou': [2113], 'Makaritsis': [2115, 2188, 2296, 2409, 2474, 2668, 2784, 2841, 2902, 3218, 3278, 3362], 'Nomikos': [2117], 'Papavasileiou': [2119, 3222], 'Pitsavos': [2121], 'Plomaritoglou': [2123], 'Spengos': [2125, 2563], 'Tziomalos': [2127], 'Tselepis': [2129], 'Liberopoulos': [2133], 'E': [2134], 'Recommendations': [2139], 'lipid': [2141], 'modification': [2142], 'attack:': [2151], 'guide': [2154, 2599], 'Hellenic': [2157, 2162, 2608, 2614, 2617, 2757], 'Organization': [2159], 'Atherosclerosis': [2163, 3177], 'Society,': [2164], '10.1177/1747493020971970,': [2169], '16:6,': [2170], '(738-750),': [2171], '1-Aug-2021.': [2175, 2218], 'Leventis': [2180, 2280, 2660], 'Samara': [2182], 'Statin': [2198], 'treatment': [2199, 2679], 'outcomes': [2201, 3327], 'Internal': [2208, 2812], 'Emergency': [2210], '10.1007/s11739-021-02743-7,': [2212], '16:5,': [2213], '(1261-1266),': [2214], 'Wintermark': [2221], 'Michel': [2224, 2261, 2300, 2414, 2479, 2788, 2843, 2907, 3283, 3364], 'Supracardiac': [2227], 'atherosclerosis': [2228, 2960], 'underestimated': [2236], '10.1093/eurheartj/ehaa218,': [2241], '42:18,': [2242], '(1789-1796),': [2243], '7-May-2021.': [2247], 'Strambo': [2248, 2284, 2397, 2462, 2772, 2829, 2890, 3266, 3350], 'Sirimarco': [2250, 2288, 2395, 2460, 2770, 2827, 2888, 3264, 3348], 'Nannoni': [2252, 2290], 'Patent': [2270, 2311], 'Foramen': [2271, 2312], 'Ovale,': [2272], '52:5,': [2274], '(1643-1652),': [2275], '1-May-2021.': [2279], 'Cardiopathy': [2307], 'Likely': [2309], 'Pathogenic': [2310], 'Ovale': [2313], 'Source,': [2319, 2973, 3185, 3300], 'Thrombosis': [2320], 'Haemostasis,': [2322], '10.1055/s-0040-1715831,': [2323], '121:03,': [2324], '(361-365),': [2325], '1-Mar-2021.': [2329], 'Qiu': [2332], 'Dintica': [2334], 'Shang': [2336], 'Calderón': [2338], 'Larrañaga': [2339], 'Xu': [2344], 'W': [2345], 'Shared': [2347], 'protective': [2350], 'factors': [2351], 'between': [2352], "Alzheimer's": [2353, 2362], 'stroke:': [2357], 'population‐based': [2359], 'longitudinal': [2360], 'study,': [2361], 'Dementia,': [2364], '10.1002/alz.12203,': [2365], '17:2,': [2366], '(191-204),': [2367], '1-Feb-2021.': [2371], '樋口': [2372], '義,': [2373], '平山': [2374], '篤': [2375], '児玉': [2377], '和': [2378], '原因不明とされる脳梗塞症例の塞栓源探索に対する血管内視鏡を用いた大動脈破綻プラーク観察の有効性に関して,': [2380], 'JCS': [2383], 'Cardiologists,': [2384], '10.1253/jjcsc.30.0_35,': [2385], '30:0,': [2386], '(35-42),': [2387], '.': [2388], 'Lambrou': [2393, 2458, 2825, 2886, 3262], 'Eskandari': [2399, 2464, 2774, 2831, 2892, 3268, 3352], 'Vemmou': [2403, 2468, 2778, 2835, 2896, 3095, 3272, 3356], 'low': [2427], 'incident': [2431, 2800], 'fibrillation:': [2433], 'AF-ESUS': [2435, 2867], 'score,': [2436], '10.1177/1747493020925281,': [2441], '16:1,': [2442], '(29-38),': [2443], '1-Jan-2021.': [2447, 2505], 'Weng': [2450], 'Akyea': [2454], 'Condon': [2456], 'Data‐driven': [2482], 'machine‐learning': [2483], '10.1111/ene.14524,': [2499], '28:1,': [2500], '(192-201),': [2501], 'Beheshtian': [2506], 'Pakpoor': [2508], 'Huntley': [2510], 'Sahraian': [2512], 'Urrutia': [2514], 'Khan': [2516], 'Idowu': [2518], 'O': [2519], 'Yousem': [2521], 'D': [2522], 'Vascular': [2524], 'imaging': [2525], 'initial': [2528], 'Imaging,': [2535], '10.1016/j.clinimag.2020.07.013,': [2536], '68,': [2537], '(278-282),': [2538], '1-Dec-2020.': [2542], 'Tzikas': [2545], 'Vavouranakis': [2547], 'Nikas': [2549], 'Katsimagklis': [2551], 'Koroboki': [2553, 2780, 2837, 2898, 3274, 3358], 'Manolis': [2555], 'Papadopoulos': [2559], 'Sideris': [2561], 'Toutouzas': [2565], 'Tziakas': [2567], 'Vassilopoulou': [2569], 'Kanakakis': [2571], 'Tsioufis': [2576, 2741], 'Expert': [2579], 'consensus': [2580], 'statement': [2581], 'ovale:': [2596], 'working': [2602], 'group': [2603], 'Organization,': [2616], 'Cardiology,': [2620, 2760, 2980], '10.1016/j.hjc.2020.02.001,': [2621], '61:6,': [2622], '(435-441),': [2623], '1-Nov-2020.': [2627], 'Role': [2643], 'Echocardiography': [2645], 'Screening': [2646], 'Unit,': [2650], 'Frontiers': [2651], '10.3389/fneur.2020.01003,': [2654], '11': [2655], 'Pearce': [2664, 2697, 3143], 'Antithrombotic': [2678], 'supracardiac': [2685], '10.1212/WNL.0000000000009823,': [2688], '95:5,': [2689], '(e499-e507),': [2690], '4-Aug-2020.': [2694], 'S': [2714, 2941, 3170, 3231], 'Potential': [2719, 3290], 'Sources': [2721, 3292], 'NAVIGATE-ESUS': [2732], 'Trial,': [2733], '51:6,': [2735], '(1797-1804),': [2736], '1-Jun-2020.': [2740], 'patients:': [2749], "don't": [2750], 'put': [2751], 'blame': [2753], 'always': [2754], 'heart,': [2756], '10.1016/j.hjc.2018.07.003,': [2761], '61:3,': [2762], '(208-209),': [2763], '1-May-2020.': [2767, 2820], 'Left': [2794], 'diameter': [2796], 'thresholds': [2797], '10.1016/j.ejim.2020.01.002,': [2814], '75,': [2815], '(30-34),': [2816], 'Supraventricular': [2849], 'Extrasystoles': [2850], 'Standard': [2852], '12-lead': [2853], 'Electrocardiogram': [2854], 'Predict': [2855], 'New': [2856, 2920, 3432], 'Incident': [2857, 2921], 'Study,': [2868], '10.1016/j.jstrokecerebrovasdis.2019.104626,': [2875], '29:4,': [2876], '(104626),': [2877], '1-Apr-2020.': [2881], '(2019)': [2909, 3048, 3106, 3174, 3235, 3285, 3317, 3369], 'External': [2910], 'Performance': [2911], 'HAVOC': [2914], 'Score': [2915], 'Prediction': [2918, 3113], 'Fibrillation,': [2923], '51:2,': [2925], '(457-461),': [2926], '1-Feb-2020.': [2930], 'Zhu': [2931], 'Shu': [2933], 'Jiang': [2935], 'Mean': [2943], 'platelet': [2944, 2948], 'volume': [2945], 'mean': [2947], 'volume/platelet': [2949], 'count': [2950], 'ratio': [2951], 'nonvalvular': [2953], '10.1097/MD.0000000000021044,': [2963], '99:28,': [2964], '(e21044)': [2965], 'College': [2978], '10.1016/j.jacc.2019.11.024,': [2981], '75:3,': [2982], '(333-340),': [2983], '1-Jan-2020.': [2987, 3040], 'Lin': [2988], 'Cui': [2990], 'Chen': [2992], 'van': [2994], 'Engelen': [2995], 'Bruijne': [2998], 'Azarpazhooh': [3000], 'Sohrevardi': [3002], 'Spence': [3004], 'Chiu': [3007], 'B': [3008], 'Longitudinal': [3010], 'texture': [3015], 'three-dimensional': [3017], 'ultrasound': [3018], 'images': [3019], 'based': [3020], 'semi-supervised': [3022], 'graph-based': [3023], 'dimensionality': [3024], 'reduction': [3025], 'feature': [3027], 'selection,': [3028], 'Computers': [3029], 'Biology': [3031], '10.1016/j.compbiomed.2019.103586,': [3034], '116,': [3035], '(103586),': [3036], 'Oral': [3049], 'anticoagulation': [3050], 'versus': [3051], 'antiplatelet': [3052], 'placebo': [3054], 'failure': [3062], 'sinus': [3064], 'rhythm:': [3065], 'review': [3067], 'meta-analysis': [3069], 'controlled': [3072], '10.1177/1747493019877296,': [3078], '14:9,': [3079], '(856-861),': [3080], '1-Dec-2019.': [3084, 3140], 'Stamatelopoulos': [3089], 'Masi': [3099], 'Comparison': [3107], 'Scores': [3110], 'Overall': [3116], 'Stroke:': [3123], 'Athens': [3125], 'Registry,': [3127], '10.1016/j.jstrokecerebrovasdis.2019.104415,': [3134], '28:12,': [3135], '(104415),': [3136], 'Meseguer': [3145, 3210], 'Sen': [3167], 'Aortic': [3175], 'Arch': [3176], '50:11,': [3187], '(3184-3190),': [3188], '1-Nov-2019.Ntaios': [3192], 'Swaminathan': [3194], 'Siegler': [3202], 'Cucchiara': [3214], 'Camps-Renom': [3216], 'Marti-Fabregas': [3224], 'Efficacy': [3236], 'Safety': [3238], 'Carotid': [3250, 3370], 'Atherosclerosis,': [3251], '50:9,': [3253], '(2477-2485),': [3254], '1-Sep-2019.Ntaios': [3258], 'Prevalence': [3286], 'Overlap': [3288], '8:15,': [3307], '6-Aug-2019.': [3311], 'Low-density': [3318], 'lipoprotein': [3319], 'cholesterol': [3320], 'lowering': [3321], 'cardiovascular': [3326], '10.1177/1747493019851283,': [3337], '14:5,': [3338], '(476-482),': [3339], '1-Jul-2019.': [3343], 'plaques': [3371], 'detection': [3373], '10.1212/WNL.0000000000007611,': [3384], '92:23,': [3385], '(e2644-e2652),': [3386], '4-Jun-2019.': [3390], 'Kerut': [3391], 'Campbell': [3393], 'Hall': [3395], 'McMullan': [3398], '(2018)': [3400, 3426], 'candidates': [3403], 'closure': [3406], 'echocardiography': [3409], 'laboratory,': [3410], 'Echocardiography,': [3411], '10.1111/echo.14154,': [3412], '35:11,': [3413], '(1860-1867),': [3414], '1-Nov-2018.': [3418], 'Mi': [3419], 'Block': [3421], 'Broderick': [3424], 'Closure': [3428], 'England': [3433], '10.1056/NEJMclde1715853,': [3437], '378:17,': [3438], '(1639-1642),': [3439], '26-Apr-2018.': [3443], 'December': [3444], '19,': [3445, 3462], '2017Vol': [3446], 'Issue': [3448], '25': [3449], 'Advertisement': [3450, 3467], 'Article': [3451], 'InformationMetrics': [3452], '©': [3453], '2017': [3454, 3463], 'Inc.https://doi.org/10.1161/CIRCULATIONAHA.117.030509PMID:': [3458], '29255121': [3459], 'publishedDecember': [3461], 'Keywordspathophysiologyetiologyclassificationembolic': [3464], 'strokePDF': [3465], 'download': [3466], 'SubjectsIschemic': [3468]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4232858418', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 13}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 18}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 2}], 'updated_date': '2024-09-11T01:59:07.710077', 'created_date': '2022-05-12'}