Title: The 27th Annual Meeting of the Society for Hard Tissue Regenerative Biology
Abstract: In the space, where the gravity is extremely small, osteoporosis-like syndrome occur in astronauts.Thus, the astronauts who stayed in the international space station (ISS) for long time cannot stand alone for a while after the return to the earth.To study this phenomenon, our team focused on the cell morphology observed on the surface of regenerating fish scales under microgravity.So, we had established several special methods for the experiments in the ISS and set up Uroko-Laboratory in our university to prepare the materials.STS-132 (space shuttle Atlantis) was launched successfully on May 14, 2010 and our space experiments i.e., culture of fish scales under microgravity, were carried out.As a result, the activation of osteoclast was demonstrated by the bone absorption and the morphological changes.