Publication Information

{'id': 'https://openalex.org/W3152670291', 'doi': 'https://doi.org/10.3389/fnut.2021.660598', 'title': 'Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites', 'display_name': 'Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites', 'publication_year': 2021, 'publication_date': '2021-04-16', 'ids': {'openalex': 'https://openalex.org/W3152670291', 'doi': 'https://doi.org/10.3389/fnut.2021.660598', 'mag': '3152670291', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33954162', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8092122'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fnut.2021.660598', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fnut.2021.660598/pdf', 'source': 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'observe': [101], 'pathological': [103], 'changes': [104], 'colon,': [107], 'histological': [109], 'myeloperoxidase': [115], '(MPO)': [116], 'tissue': [120, 149], 'Western': [123], 'blot': [124], 'immunohistochemistry': [126], 'detect': [130], 'expressions': [132, 139, 156, 228, 249, 258, 269, 279], 'Claudin-1,': [134, 230], 'Occludin,': [135, 231], 'ZO-1.': [137], 'IL-1β,': [141, 251], 'IL-6,': [142, 252], 'IL-10,': [143], 'TNF-α,': [144], 'TGF-β': [146, 262], 'in': [147, 201, 223, 234, 239, 302, 317, 325, 339], 'detected': [151, 165], 'ELISA.': [153], 'MUC2,': [158], 'Reg3γ,': [159], 'β-defensin': [160, 273], '(HBD-2),': [161], 'cAMP': [163, 283], 'immunofluorescence': [167], '(IF).': [168], '16S': [169, 287], 'rDNA': [170, 288], 'sequencing': [171, 289], 'determined': [172], 'type': [174], 'structure': [176, 334], 'flora.': [179, 191, 351], 'Liquid': [180], 'chromatography–tandem': [181], 'mass': [182], 'spectrometry': [183], '(LC-MS/MS)': [184], 'measured': [185], 'metabolites': [187, 347], 'Results:': [192], 'Compared': [193], 'with': [194, 244, 307], 'group,': [197], "mice's": [199], 'weight': [200], 'group': [204, 242], 'higher': [206, 222], 'longer.': [214], 'At': [215], '14th': [217], 'day,': [218], 'MPO': [219], 'group.': [226, 247], 'ZO-1': [233], 'up-regulated': [238], 'compared': [243], 'TNF-α': [254], 'lower.': [256], 'IL-10': [260], 'higher.': [264], 'IF': [265], 'showed': [266, 291, 311], 'MUC2': [271], '(HBD-2)': [274], 'down-regulated,': [276], 'Reg3γ': [281], 'up-regulated.': [285], 'results': [290, 310], 'alpha': [294], 'diversity': [295, 298], 'beta': [297], 'notably': [300], 'changed': [301, 314, 343], 'treated': [306], 'BL.': [308], 'Metabolomics': [309], 'purine': [315], 'metabolism': [316], 'Conclusion:': [321], 'alleviated': [323], 'improving': [328], 'inflammatory': [330], 'response': [331], 'barrier': [338], 'colon.': [341], 'composition': [345], 'Thus,': [352], 'might': [354], 'be': [355], 'an': [356], 'effective': [357], 'nutritional': [358], 'supplement': [359], 'for': [360], 'treatment.': [362]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3152670291', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 2}], 'updated_date': '2024-09-18T20:56:32.147156', 'created_date': '2021-04-26'}