Title: Prediction of metabolic syndrome with combination of waist-to-hip ratio (or waist circumference) and blood pressure measurements
Abstract: Objective To clarify which component plays a pivotal role in metabolic syndrome (MS) which is associated with an elevated risk for cardiovascular diseases and type 2 diabetes. Methods A total of 15564 participants (aged≥25 years old) with high risk for type 2 diabetes in the 1994 National Diabetes Mellitus Surveywere included in this analysis. MS was diagnosed according to the 1999 WHO criteria, and insulin resistance (IR) was defined as being above the 75th percentile of HOMA-IR of the population aged 25-74 years with normal glucose tolerance. Multiple logistic stepwise regression analysis was used to identify the contribution of each component to MS. Results The unadjusted and age-adjusted prevalences of MS in this population was 64.35% and 59.00%, respectively. Age, sex, systolic blood pressure(SBP), diastolic blood pressure(DBP), waist to hip ratio (WHR)/waist circumference and body mass index(BMI), but not IR, plasma glucose level, and plasma triglyceride level, were independently associated with MS, with predicted concordance of 93.8%. The combination of WHR, BMI, SBP, and DBP accounted for 90.2% of the variance of MS, and if BMI was deleted, the remaining three items accounted for 86.1% of the variance. An increment of 0.05 in WHR, or 5 cm in waist circumference, or 10 mm Hg in SBP, or 5 mm Hg in DBP, or 5 kg/m 2in BMI would elevate the risk for MS by 3.35 times, 1.87 times, 1.52 times, 1.46 times, or 1.34 times, respectively. Conclusion The combination of WHR/waist circumference and blood pressure can be used as a simplepredictor for MS in clinical practice.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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Cited By Count: 1
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