Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3128019055', 'doi': 'https://doi.org/10.7326/m20-0202', 'title': 'The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt', 'display_name': 'The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt', 'publication_year': 2021, 'publication_date': '2021-05-01', 'ids': {'openalex': 'https://openalex.org/W3128019055', 'doi': 'https://doi.org/10.7326/m20-0202', 'mag': '3128019055', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/33524293'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/m20-0202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5071323583', 'display_name': 'Christophe Bureau', 'orcid': 'https://orcid.org/0000-0001-8634-9278'}, 'institutions': [{'id': 'https://openalex.org/I3019448017', 'display_name': 'Centre Hospitalier Universitaire de Toulouse', 'ror': 'https://ror.org/017h5q109', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019448017']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Christophe Bureau', 'raw_affiliation_strings': ['Centre Hospitalier Universitaire de Toulouse'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier Universitaire de Toulouse', 'institution_ids': ['https://openalex.org/I3019448017']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004361418', 'display_name': 'Dominique Thabut', 'orcid': 'https://orcid.org/0000-0002-9658-0323'}, 'institutions': [{'id': 'https://openalex.org/I4210121705', 'display_name': 'Pitié-Salpêtrière Hospital', 'ror': 'https://ror.org/02mh9a093', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210121705']}, {'id': 'https://openalex.org/I39804081', 'display_name': 'Sorbonne Université', 'ror': 'https://ror.org/02en5vm52', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I39804081']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Dominique Thabut', 'raw_affiliation_strings': ['CHU Pitié-Salpêtrière [AP-HP]'], 'affiliations': [{'raw_affiliation_string': 'CHU Pitié-Salpêtrière [AP-HP]', 'institution_ids': ['https://openalex.org/I4210121705', 'https://openalex.org/I39804081']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019719279', 'display_name': 'Caroline Jézéquel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210116274', 'display_name': 'CIC Rennes', 'ror': 'https://ror.org/02baj6743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210105774', 'https://openalex.org/I4210116274', 'https://openalex.org/I4210155724', 'https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I4210124872', 'display_name': 'Hôpital Pontchaillou', 'ror': 'https://ror.org/02r25sw81', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124872', 'https://openalex.org/I4210155724']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Caroline Jezequel', 'raw_affiliation_strings': ['CHU Pontchaillou [Rennes]', "Centre d'Investigation Clinique [Rennes]"], 'affiliations': [{'raw_affiliation_string': "Centre d'Investigation Clinique [Rennes]", 'institution_ids': ['https://openalex.org/I4210116274']}, {'raw_affiliation_string': 'CHU Pontchaillou [Rennes]', 'institution_ids': ['https://openalex.org/I4210124872']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090701850', 'display_name': 'Isabelle Archambeaud', 'orcid': 'https://orcid.org/0000-0003-3427-4854'}, 'institutions': [{'id': 'https://openalex.org/I3019204325', 'display_name': 'Centre Hospitalier Universitaire de Nantes', 'ror': 'https://ror.org/05c1qsg97', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019204325']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Isabelle Archambeaud', 'raw_affiliation_strings': ['Centre hospitalier universitaire de Nantes'], 'affiliations': [{'raw_affiliation_string': 'Centre hospitalier universitaire de Nantes', 'institution_ids': ['https://openalex.org/I3019204325']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004064806', 'display_name': 'Louis d’Alteroche', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210095477', 'display_name': 'Centre Hospitalier Universitaire de Tours', 'ror': 'https://ror.org/00jpq0w62', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210095477']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Louis D’alteroche', 'raw_affiliation_strings': ['CHU Trousseau [Tours]'], 'affiliations': [{'raw_affiliation_string': 'CHU Trousseau [Tours]', 'institution_ids': ['https://openalex.org/I4210095477']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073789519', 'display_name': 'Sébastien Dharancy', 'orcid': 'https://orcid.org/0000-0002-8262-5607'}, 'institutions': [{'id': 'https://openalex.org/I3018718406', 'display_name': 'Centre Hospitalier Universitaire de Lille', 'ror': 'https://ror.org/02ppyfa04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018718406']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sêbastien Dharancy', 'raw_affiliation_strings': ['CHU Lille'], 'affiliations': [{'raw_affiliation_string': 'CHU Lille', 'institution_ids': ['https://openalex.org/I3018718406']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087228377', 'display_name': 'Patrick Borentain', 'orcid': 'https://orcid.org/0000-0003-0397-3070'}, 'institutions': [{'id': 'https://openalex.org/I4210162909', 'display_name': 'Hôpital de la Timone', 'ror': 'https://ror.org/05jrr4320', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210162909']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Patrick Borentain', 'raw_affiliation_strings': ['Hôpital de la Timone [CHU - APHM]'], 'affiliations': [{'raw_affiliation_string': 'Hôpital de la Timone [CHU - APHM]', 'institution_ids': ['https://openalex.org/I4210162909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075393352', 'display_name': 'Frédéric Oberti', 'orcid': 'https://orcid.org/0000-0002-1799-8837'}, 'institutions': [{'id': 'https://openalex.org/I4210112910', 'display_name': "Centre Hospitalier Universitaire d'Angers", 'ror': 'https://ror.org/0250ngj72', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210112910']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Frederic Oberti', 'raw_affiliation_strings': ["Centre Hospitalier Universitaire d'Angers"], 'affiliations': [{'raw_affiliation_string': "Centre Hospitalier Universitaire d'Angers", 'institution_ids': ['https://openalex.org/I4210112910']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003113168', 'display_name': 'Aurélie Plessier', 'orcid': 'https://orcid.org/0000-0001-5656-1622'}, 'institutions': [{'id': 'https://openalex.org/I2799502834', 'display_name': 'Hôpital Beaujon', 'ror': 'https://ror.org/03jyzk483', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799502834', 'https://openalex.org/I4210097159']}, {'id': 'https://openalex.org/I4210094149', 'display_name': 'Hôpital Beau-Séjour', 'ror': 'https://ror.org/00ntwgk39', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094149']}], 'countries': ['CH', 'FR'], 'is_corresponding': False, 'raw_author_name': 'Aurélie Plessier', 'raw_affiliation_strings': ['Hôpital Beaujon [AP-HP]'], 'affiliations': [{'raw_affiliation_string': 'Hôpital Beaujon [AP-HP]', 'institution_ids': ['https://openalex.org/I2799502834', 'https://openalex.org/I4210094149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048237873', 'display_name': 'Victor de Lédinghen', 'orcid': 'https://orcid.org/0000-0001-6414-1951'}, 'institutions': [{'id': 'https://openalex.org/I3018323443', 'display_name': 'Centre Hospitalier Universitaire de Bordeaux', 'ror': 'https://ror.org/01hq89f96', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018323443']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Victor de Ledinghen', 'raw_affiliation_strings': ['CHU Bordeaux [Bordeaux]'], 'affiliations': [{'raw_affiliation_string': 'CHU Bordeaux [Bordeaux]', 'institution_ids': ['https://openalex.org/I3018323443']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079013335', 'display_name': 'Nathalie Ganne–Carrié', 'orcid': 'https://orcid.org/0000-0002-7351-5027'}, 'institutions': [{'id': 'https://openalex.org/I4210139963', 'display_name': 'Génomique Fonctionnelle des Tumeurs Solides', 'ror': 'https://ror.org/03yc0ew57', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I169173203', 'https://openalex.org/I204730241', 'https://openalex.org/I39804081', 'https://openalex.org/I4210139963']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nathalie Ganne-Carrié', 'raw_affiliation_strings': ['Génomique Fonctionnelle des Tumeurs Solides'], 'affiliations': [{'raw_affiliation_string': 'Génomique Fonctionnelle des Tumeurs Solides', 'institution_ids': ['https://openalex.org/I4210139963']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003944446', 'display_name': 'Nicolas Carbonell', 'orcid': 'https://orcid.org/0000-0001-7572-5581'}, 'institutions': [{'id': 'https://openalex.org/I4210102928', 'display_name': 'Hôpital Saint-Antoine', 'ror': 'https://ror.org/01875pg84', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210102928']}, {'id': 'https://openalex.org/I39804081', 'display_name': 'Sorbonne Université', 'ror': 'https://ror.org/02en5vm52', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I39804081']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nicolas Carbonell', 'raw_affiliation_strings': ['CHU Saint-Antoine [AP-HP]'], 'affiliations': [{'raw_affiliation_string': 'CHU Saint-Antoine [AP-HP]', 'institution_ids': ['https://openalex.org/I4210102928', 'https://openalex.org/I39804081']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060691425', 'display_name': 'Vanessa Rousseau', 'orcid': 'https://orcid.org/0000-0001-7518-7891'}, 'institutions': [{'id': 'https://openalex.org/I3019448017', 'display_name': 'Centre Hospitalier Universitaire de Toulouse', 'ror': 'https://ror.org/017h5q109', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019448017']}, {'id': 'https://openalex.org/I4210145991', 'display_name': 'Centre de recherche cerveau et cognition', 'ror': 'https://ror.org/04fhrs205', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I134560555', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210145991']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Vanessa Rousseau', 'raw_affiliation_strings': ['Centre Hospitalier Universitaire de Toulouse', 'Institut des sciences du cerveau de Toulouse.'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier Universitaire de Toulouse', 'institution_ids': ['https://openalex.org/I3019448017']}, {'raw_affiliation_string': 'Institut des sciences du cerveau de Toulouse.', 'institution_ids': ['https://openalex.org/I4210145991']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069068175', 'display_name': 'Agnès Sommet', 'orcid': 'https://orcid.org/0000-0001-7980-5650'}, 'institutions': [{'id': 'https://openalex.org/I3019448017', 'display_name': 'Centre Hospitalier Universitaire de Toulouse', 'ror': 'https://ror.org/017h5q109', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019448017']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Agnès Sommet', 'raw_affiliation_strings': ['Centre Hospitalier Universitaire de Toulouse'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier Universitaire de Toulouse', 'institution_ids': ['https://openalex.org/I3019448017']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023044832', 'display_name': 'Luigi Terracciano', 'orcid': 'https://orcid.org/0000-0002-9393-9660'}, 'institutions': [{'id': 'https://openalex.org/I3019448017', 'display_name': 'Centre Hospitalier Universitaire de Toulouse', 'ror': 'https://ror.org/017h5q109', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019448017']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean Marie Péron', 'raw_affiliation_strings': ['Centre Hospitalier Universitaire de Toulouse'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier Universitaire de Toulouse', 'institution_ids': ['https://openalex.org/I3019448017']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5062077592', 'display_name': 'Jean Pierre Vinel', 'orcid': 'https://orcid.org/0000-0001-8954-5231'}, 'institutions': [{'id': 'https://openalex.org/I3019448017', 'display_name': 'Centre Hospitalier Universitaire de Toulouse', 'ror': 'https://ror.org/017h5q109', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019448017']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean Pierre Vinel', 'raw_affiliation_strings': ['Centre Hospitalier Universitaire de Toulouse'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier Universitaire de Toulouse', 'institution_ids': ['https://openalex.org/I3019448017']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 16, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 15.964, 'has_fulltext': False, 'cited_by_count': 100, 'citation_normalized_percentile': {'value': 0.999784, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '174', 'issue': '5', 'first_page': '633', 'last_page': '640'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10337', 'display_name': 'Liver Cirrhosis and Associated Complications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10337', 'display_name': 'Liver Cirrhosis and Associated Complications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10351', 'display_name': 'Epidemiology and Management of NAFLD', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10999', 'display_name': 'Liver Transplantation and Graft Survival Analysis', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rifaximin', 'display_name': 'Rifaximin', 'score': 0.9904586}, {'id': 'https://openalex.org/keywords/hepatic-encephalopathy', 'display_name': 'Hepatic encephalopathy', 'score': 0.88618296}, {'id': 'https://openalex.org/keywords/transjugular-intrahepatic-portosystemic-shunt', 'display_name': 'Transjugular Intrahepatic Portosystemic Shunt', 'score': 0.580694}, {'id': 'https://openalex.org/keywords/rescue-therapy', 'display_name': 'Rescue therapy', 'score': 0.53430474}, {'id': 'https://openalex.org/keywords/portosystemic-shunt', 'display_name': 'Portosystemic shunt', 'score': 0.51823187}], 'concepts': [{'id': 'https://openalex.org/C2778889925', 'wikidata': 'https://www.wikidata.org/wiki/Q416073', 'display_name': 'Rifaximin', 'level': 3, 'score': 0.9904586}, {'id': 'https://openalex.org/C2781033279', 'wikidata': 'https://www.wikidata.org/wiki/Q1438498', 'display_name': 'Transjugular intrahepatic portosystemic shunt', 'level': 4, 'score': 0.948329}, {'id': 'https://openalex.org/C2780325230', 'wikidata': 'https://www.wikidata.org/wiki/Q642548', 'display_name': 'Hepatic encephalopathy', 'level': 3, 'score': 0.88618296}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7164124}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.58190995}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.5640448}, {'id': 'https://openalex.org/C2776485726', 'wikidata': 'https://www.wikidata.org/wiki/Q17141389', 'display_name': 'Rescue therapy', 'level': 2, 'score': 0.53430474}, {'id': 'https://openalex.org/C2778674827', 'wikidata': 'https://www.wikidata.org/wiki/Q2105264', 'display_name': 'Portosystemic shunt', 'level': 4, 'score': 0.51823187}, {'id': 'https://openalex.org/C2780968331', 'wikidata': 'https://www.wikidata.org/wiki/Q1890115', 'display_name': 'Shunt (medical)', 'level': 2, 'score': 0.45890254}, {'id': 'https://openalex.org/C2778808290', 'wikidata': 'https://www.wikidata.org/wiki/Q124604', 'display_name': 'Portal hypertension', 'level': 3, 'score': 0.37793544}, {'id': 'https://openalex.org/C2777214474', 'wikidata': 'https://www.wikidata.org/wiki/Q147778', 'display_name': 'Cirrhosis', 'level': 2, 'score': 0.28789335}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.08039054}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005765', 'descriptor_name': 'Gastrointestinal Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006501', 'descriptor_name': 'Hepatic Encephalopathy', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D008103', 'descriptor_name': 'Liver Cirrhosis', 'qualifier_ui': 'Q000601', 'qualifier_name': 'surgery', 'is_major_topic': True}, {'descriptor_ui': 'D019168', 'descriptor_name': 'Portasystemic Shunt, Transjugular Intrahepatic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000078262', 'descriptor_name': 'Rifaximin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001201', 'descriptor_name': 'Ascites', 'qualifier_ui': 'Q000601', 'qualifier_name': 'surgery', 'is_major_topic': False}, {'descriptor_ui': 'D001201', 'descriptor_name': 'Ascites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005602', 'descriptor_name': 'France', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005765', 'descriptor_name': 'Gastrointestinal Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006471', 'descriptor_name': 'Gastrointestinal Hemorrhage', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D006471', 'descriptor_name': 'Gastrointestinal Hemorrhage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006501', 'descriptor_name': 'Hepatic Encephalopathy', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D006501', 'descriptor_name': 'Hepatic Encephalopathy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008103', 'descriptor_name': 'Liver Cirrhosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000078262', 'descriptor_name': 'Rifaximin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/m20-0202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-03229022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.science/hal-03229022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/33524293', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.65, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 32, 'referenced_works': ['https://openalex.org/W1992548863', 'https://openalex.org/W1996571028', 'https://openalex.org/W1999133483', 'https://openalex.org/W2003796334', 'https://openalex.org/W2019515792', 'https://openalex.org/W2026352845', 'https://openalex.org/W2031365879', 'https://openalex.org/W2050236103', 'https://openalex.org/W2099360240', 'https://openalex.org/W2105932465', 'https://openalex.org/W2134599653', 'https://openalex.org/W2138196119', 'https://openalex.org/W2186320679', 'https://openalex.org/W2511281246', 'https://openalex.org/W2521555087', 'https://openalex.org/W2533741811', 'https://openalex.org/W2612202127', 'https://openalex.org/W2725248201', 'https://openalex.org/W2787222819', 'https://openalex.org/W2798110052', 'https://openalex.org/W2800798643', 'https://openalex.org/W2802906787', 'https://openalex.org/W2893430512', 'https://openalex.org/W2901861115', 'https://openalex.org/W2904390994', 'https://openalex.org/W2911083146', 'https://openalex.org/W2912997221', 'https://openalex.org/W2914015239', 'https://openalex.org/W2947271233', 'https://openalex.org/W2948306237', 'https://openalex.org/W2969880458', 'https://openalex.org/W4292028675'], 'related_works': ['https://openalex.org/W3181884525', 'https://openalex.org/W3118321514', 'https://openalex.org/W2987737929', 'https://openalex.org/W2979561317', 'https://openalex.org/W2809943007', 'https://openalex.org/W2791173279', 'https://openalex.org/W2624537902', 'https://openalex.org/W2088144781', 'https://openalex.org/W2047084558', 'https://openalex.org/W2019985848'], 'abstract_inverted_index': {'The': [0, 183], 'efficacy': [1, 92], 'of': [2, 8, 63, 97, 108, 119, 155, 186, 222], 'rifaximin': [3, 38, 71, 123, 187, 204], 'in': [4, 19, 24, 112, 121, 134], 'the': [5, 89, 104, 122, 135, 142, 153, 165, 180, 210], 'secondary': [6], 'prevention': [7, 62], 'overt': [9, 40, 98, 109, 213], 'hepatic': [10], 'encephalopathy': [11], '(HE)': [12], 'is': [13], 'well': [14, 206], 'documented,': [15], 'but': [16], 'its': [17], 'effectiveness': [18], 'preventing': [20], 'a': [21], 'first': [22], 'episode': [23, 107], 'patients': [25, 53, 120, 173, 198], 'after': [26, 42, 88, 103, 190], 'transjugular': [27], 'intrahepatic': [28], 'portosystemic': [29], 'shunt': [30], '(TIPS)': [31], 'has': [32], 'not': [33], 'been': [34], 'established.To': [35], 'determine': [36], 'whether': [37], 'prevents': [39], 'HE': [41, 99, 110], 'TIPS': [43, 57, 82, 105, 191], 'compared': [44], 'with': [45, 54, 174, 199, 202], 'placebo.Randomized,': [46], 'double-blind,': [47], 'multicenter,': [48], 'placebo-controlled': [49], 'trial.': [50], '(ClinicalTrials.gov:': [51], 'NCT02016196).197': [52], 'cirrhosis': [55, 200], 'undergoing': [56], 'for': [58, 85, 212, 220], 'intractable': [59], 'ascites': [60], 'or': [61, 76], 'variceal': [64], 'rebleeding.Patients': [65], 'were': [66], 'randomly': [67], 'assigned': [68], 'to': [69, 117, 132, 150, 172, 195], 'receive': [70], '(600': [72], 'mg': [73], 'twice': [74], 'daily)': [75], 'placebo,': [77], 'beginning': [78], '14': [79], 'days': [80, 87, 102], 'before': [81], 'and': [83, 128, 192, 208], 'continuing': [84], '168': [86, 101], 'procedure.The': [90], 'primary': [91], 'end': [93], 'point': [94], 'was': [95, 161, 205], 'incidence': [96, 154], 'within': [100], 'procedure.An': [106], 'occurred': [111], '34%': [113], '(95%': [114], 'CI,': [115], '25%': [116], '44%)': [118], 'group': [124, 137], '(n': [125, 138], '=': [126, 139], '93)': [127, 140], '53%': [129], '(CI,': [130], '43%': [131], '63%)': [133], 'placebo': [136], 'during': [141], 'postprocedure': [143], 'period': [144], '(odds': [145], 'ratio,': [146], '0.48': [147], '[CI,': [148], '0.27': [149], '0.87]).': [151], 'Neither': [152], 'adverse': [156], 'events': [157], 'nor': [158], 'transplant-free': [159], 'survival': [160], 'significantly': [162], 'different': [163], 'between': [164], '2': [166], 'groups.The': [167], "study's": [168], 'conclusion': [169], 'applies': [170], 'mainly': [171], 'alcoholic': [175], 'cirrhosis,': [176], 'who': [177], 'made': [178], 'up': [179], 'study': [181], 'population.': [182], 'potential': [184], 'benefit': [185], '6': [188], 'months': [189], 'beyond': [193], 'remains': [194], 'be': [196, 218], 'investigated.In': [197], 'treated': [201], 'TIPS,': [203], 'tolerated': [207], 'reduced': [209], 'risk': [211], 'HE.': [214], 'Rifaximin': [215], 'should': [216], 'therefore': [217], 'considered': [219], 'prophylaxis': [221], 'post-TIPS': [223], 'HE.French': [224], 'Public': [225], 'Health': [226], 'Ministry.': [227]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3128019055', 'counts_by_year': [{'year': 2024, 'cited_by_count': 28}, {'year': 2023, 'cited_by_count': 39}, {'year': 2022, 'cited_by_count': 30}, {'year': 2021, 'cited_by_count': 3}], 'updated_date': '2024-09-01T08:58:40.960921', 'created_date': '2021-02-15'}