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{'id': 'https://openalex.org/W2964168587', 'doi': 'https://doi.org/10.1186/s40425-019-0677-y', 'title': 'First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors', 'display_name': 'First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors', 'publication_year': 2019, 'publication_date': '2019-07-24', 'ids': {'openalex': 'https://openalex.org/W2964168587', 'doi': 'https://doi.org/10.1186/s40425-019-0677-y', 'mag': '2964168587', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31340866', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6657210'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s40425-019-0677-y', 'pdf_url': 'https://jitc.bmj.com/content/jitc/7/1/195.full.pdf', 'source': {'id': 'https://openalex.org/S2754803477', 'display_name': 'Journal for ImmunoTherapy of Cancer', 'issn_l': 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[220], 'presentation-related': [221], 'genes': [222], 'Two': [226], 'additional': [227], 'gastric': [230], 'esophageal': [232], 'stable': [235], 'disease': [236], 'lasting': [237], 'least': [239], '3': [240], 'months.': [241], '<h3>Conclusions</h3>': [242], 'monotherapy': [244], 'successfully': [245], 'depleted': [246], 'manageable': [252], 'safety': [253], 'profile': [254], 'encouraging': [256], 'preliminary': [257], 'efficacy': [258], 'signals,': [259], 'warrants': [261], 'further': [262], 'investigations,': [263], 'combination': [266], 'immune': [268], 'checkpoint': [269], 'inhibitors.': [270]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2964168587', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-09-24T02:55:24.199662', 'created_date': 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