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1439], 'recent': [160, 347, 832], 'version': [161], 'article.': [164], 'Previous': [165, 1953], 'versions:': [166], 'August': [167, 1829, 1935, 1949], '30,': [168, 2390], '2018:': [169], 'Ahead': [170], 'Print': [172], 'is': [174, 211, 248, 256, 297, 869, 968, 1138, 1320, 1436, 1499, 1504, 1516], 'second': [176, 899], 'common': [178], 'single': [179], 'cause': [180, 188], 'death': [182], 'leading': [187], 'long-term': [190, 277, 788], 'disability.1,2': [191], 'Every': [192], 'year,': [193], 'up': [194, 220, 785, 1430], '1.3': [196], 'million': [197, 464, 494, 529, 537, 600, 615], 'persons': [198], 'suffer': [201], 'a': [202, 309, 346, 764, 845, 979, 1013, 1033, 1176, 1216, 1295, 1321, 1348, 1358, 1379, 1396, 1497, 1501, 1505, 1517, 1622, 1638, 1801, 1880, 2211, 2259, 2357], 'first-ever': [203], 'stroke.3': [204], 'Consequently,': [205], 'socioeconomic': [207], 'impact': [208, 1472], 'stroke': [210, 229, 255, 274, 289, 301, 314, 326, 338, 364, 378, 410, 548, 643, 769, 839, 891, 916, 931, 957, 1038, 1042, 1052, 1078, 1172, 1189, 1253, 1269, 1336, 1390, 1408, 1451, 1466, 1878, 1887, 1915, 2038, 2102, 2253, 2294, 2352, 2396], 'considerable': [212], 'with': [213, 291, 300, 481, 545, 670, 700, 711, 929, 945, 993, 1071, 1171, 1294, 1374, 2104], 'an': [214, 252, 259, 546, 954, 1085, 1248, 1341, 1482, 2115], 'annual': [215, 472, 500, 515, 522, 575, 592, 604], 'cost': [216, 1359], '€45': [222], 'billion.1': [223], 'Projections': [224], 'show': [225], 'that': [226, 251, 564, 658, 691, 738, 742, 797, 807, 926, 964, 1089, 1229, 1346], 'overall': [228, 632], 'burden': [230, 272], 'will': [233, 1238, 1287, 1310, 1394], 'further': [234], 'increase': [235, 1230, 2243], 'by': [236, 377, 844, 903, 1162, 1241, 1944], '35%': [237], '2050,': [239], 'mostly': [240, 586], 'because': [241, 262], 'aging': [244], 'population.4': [245], 'However,': [246, 316, 553], 'there': [247], 'overwhelming': [249], 'evidence': [250], 'acute': [253, 313, 337, 363, 768, 890, 930, 937, 1046, 1876, 2036, 2100, 2220], 'ischemic': [254, 474, 547, 642, 2101, 2221, 2252], 'no': [257, 853, 1688], 'longer': [258], 'unavoidable': [260], 'fate': [261], 'strokes': [263, 475, 1159], 'can': [264], 'be': [265, 611, 745, 814, 856, 941, 1239, 1288, 1311, 1338], 'prevented': [266], 'treated,': [268], 'dramatically': [269], 'reducing': [270], 'its': [276], 'consequences.Endovascular': [278], 'treatment': [279, 304, 339, 365, 939, 2142], '(EVT)': [280], 'has': [281, 812, 976, 1347], 'recently': [282], 'become': [283, 1481], 'standard': [285], 'care': [287, 668, 770, 892, 1039, 1195, 1449, 2295, 2299, 2346], 'patients': [290, 544, 570, 644, 695, 741, 928, 1170, 2103], 'large': [292, 1454], 'vessel': [293], 'occlusions,': [294], 'it': [296, 798, 804], 'now,': [298], 'together': [299], 'unit': [302], '(SU)': [303], 'intravenous': [306], 'thrombolysis': [307, 2033], '(IVT),': [308], 'main': [310], 'pillar': [311], 'management.': [315], 'despite': [318], 'much': [319], 'discussion': [320], 'on': [321, 331, 419, 800, 1063, 1252, 1858, 1867, 1913, 2153, 2367], 'necessary': [323], 'overhaul': [324], 'systems': [327], 'care,': [329], 'information': [330, 811], 'access': [332, 662], 'delivery': [334, 665, 1874], 'these': [336, 730, 758], 'strategies': [340, 1206], 'was': [343, 406, 490, 524, 579, 585, 596, 608, 796, 805, 925, 1082, 1108, 1119], 'lacking.': [344], 'In': [345, 851, 896, 1931], 'publication': [348, 1134, 1984, 2055, 2127, 2160, 2232, 2266, 2314], 'European': [351, 382, 386, 394, 438, 773, 973, 980, 995, 1102, 1123, 1242, 1387, 1433, 1745, 1752, 1891, 1914, 1923, 2307, 2362, 2369], 'Journal,': [353, 2309, 2371], 'et': [357, 1743], 'al5': [358], 'surveyed': [359, 801], 'status': [361], 'Europe.Current': [367], 'Status': [368], 'EuropeA': [374], 'survey': [375, 762, 868, 882, 962, 1881], 'drafted': [376], 'professionals': [379], 'from': [380, 434, 450, 828, 970, 1097, 1196, 1264, 1267], 'Organisation,': [384], 'Society': [387, 2363], 'Minimally': [389], 'Invasive': [390], 'Neurological': [391, 2121, 2226], 'Therapy,': [392], 'Academy': [395], 'patient': [400, 996, 1094, 1271], 'organisation': [401, 997], 'Alliance': [403, 999], 'for': [404, 587, 622, 659, 747, 753, 779, 783, 871, 885, 910, 915, 923, 936, 985, 1000, 1032, 1076, 1146, 1188, 1207, 1299, 1343, 1371, 1444, 1484, 1507, 1573, 1592, 1599, 1612, 1624, 1655, 1929, 2035, 2099, 2140, 2219, 2347], 'sent': [407], 'national': [409, 417, 460, 838, 1186, 1205, 1268, 1425, 1883], 'societies': [411, 1393, 1885], 'experts': [413, 1888], 'requesting': [414], 'best': [415, 686, 720, 809], 'available': [416, 810, 1804], 'data': [418, 461, 656, 826, 1263], 'number': [421, 487, 516, 523, 576, 593, 605, 1157], 'SUs,': [423], 'as': [424, 426, 953, 1179, 1328, 1330, 1340, 1422, 1424], 'well': [425, 1329, 1423], 'IVT': [427, 526, 557, 672, 701, 748], 'EVT': [429, 578, 674, 712, 754], 'rates,': [430], 'per': [431, 462, 470, 492, 498, 527, 536, 598, 613], 'year.': [432], 'Experts': [433], '44': [435, 1890], '51': [437], 'countries': [439, 512, 533, 555, 562, 583, 626, 651, 661, 821], 'provided': [440, 513, 580], 'data.': [441, 802, 864], 'Out': [442], '7': [445, 1147], 'nonparticipating': [446], 'countries,': [447, 619, 681], '5': [448], 'were': [449, 506, 627, 683, 933, 1152], 'Eastern': [451], 'Europe.': [452, 895], 'The': [453, 519, 574, 589, 688, 790, 960, 1002, 1057, 1080, 1117, 1301, 1684], 'authors': [454], 'compared': [455], 'both': [456, 671, 1351], 'pooled': [457], 'individual': [459], '1': [463, 493, 528, 599, 614], 'inhabitants': [465, 495, 616], '(United': [466], 'Nations': [467], 'data)': [468], '1000': [471, 499], 'incident': [473, 501, 641], '(Global': [476], 'Burden': [477], 'Disease': [479, 1747], 'Report)': [480], 'best-performing': [483, 625], 'countries.The': [484, 1434], 'estimated': [485, 520, 590, 609], 'mean': [486, 521, 591, 633], 'SUs': [489], '2.9': [491], '1.5': [497], 'strokes;': [502], 'highest': [503], 'country': [504], 'rates': [505, 535, 558, 621, 653, 675, 682, 2034], '9.2': [507], '5.8,': [509], 'respectively.': [510], 'Forty-two': [511], 'IVTs.': [518], '142': [525], 'inhabitants,': [530], 'whereas': [531, 560, 620, 647], '4': [532], 'had': [534, 556], 'above': [538, 654], '350.': [539], 'Overall,': [540, 637], '7.3%': [541], 'all': [543, 727, 780, 927, 1099, 1169], 'received': [551, 571, 645], 'IVT.': [552], '15': [554], '<5%,': [559], '6': [561], 'reported': [563, 652], 'at': [565, 1121], 'least': [566], '15%': [567], 'their': [569], 'treatment.': [573], '39': [582], '2016.': [588], 'EVTs': [595], '37.1': [597], 'inhabitants.': [601], 'Importantly,': [602], 'treatments': [607, 759], '<10': [612], '13': [618], '3': [624, 650, 2045], '3×': [628], 'higher': [629], 'than': [630, 1356], '(up': [634], '111.5).': [636], 'only': [638, 808, 2044], '1.9%': [639], 'EVT,': [646], 'top': [649, 1956], '5%.These': [655], 'showed': [657], 'SU': [667, 955, 1178], 'along': [669, 1070, 1373], 'varied': [676], 'significantly,': [677], 'far': [684, 969], 'below': [685], 'performers.': [687], 'discrepancy': [689], 'means': [690, 737], '226': [692], '662': [693], 'more': [694, 1167], 'could': [696, 855, 1479], 'have': [697, 723, 883, 1185, 1307, 1395, 1410], 'been': [698, 724, 1308, 1411], 'treated': [699], '(339': [702], '929': [703], 'instead': [704, 715], '113': [706], '267)': [707], '67': [709], '347': [710], '(94': [713], '852': [714], '27': [717], '505),': [718], 'if': [719], 'practice': [721], 'would': [722, 743], 'followed': [725], 'countries.': [728, 774, 1103, 1388, 1892], 'Although': [729, 803], 'still': [732, 967], 'rather': [733, 1355], 'conservative': [734], 'estimates,': [735], 'two-thirds': [739], 'potentially': [744, 934], 'eligible': [746, 935], 'three-quarters': [750], 'candidates': [752], 'did': [755], 'not': [756, 1696], 'receive': [757], 'Europe.This': [761], 'provides': [763, 1142], 'comprehensive': [765, 1440], 'snapshot': [766], 'standards': [771, 893], 'These': [775], 'results': [776], 'valuable': [778], 'stakeholders': [781], 'responsible': [782], 'drawing': [784], 'implementing': [787], 'strategies.': [789], 'major': [791], 'limitation': [792], 'investigation': [795], 'relied': [799], 'requested': [806], 'utilized': [815], 'compile': [817], 'survey,': [819], 'lacking': [822], 'organized': [823], 'nationwide': [824], 'registries,': [825, 840], 'came': [827], 'variable': [829], 'sources,': [830], 'namely': [831], 'health': [833, 1210, 1471], 'ministerial': [834], 'statistics,': [835], 'service': [836], 'reports,': [837], 'estimates': [842], 'made': [843], 'consensus': [846, 1106], 'coordinators': [848], 'experts.': [850], 'addition,': [852], 'audit': [854], 'performed': [857], 'assess': [859], 'quality': [861, 1055, 1265, 1426], 'A': [865, 1104, 1538, 2202, 2236], 'larger': [866], 'prospective': [867], 'planned': [870], '2019.Perspective': [872], 'EuropeThe': [878], 'findings': [879], 'implications': [884], 'future': [887], 'organization': [888, 1095], 'throughout': [894], '2006,': [897], 'Helsingborg': [900, 1010, 1910], 'Declaration,': [901], 'cosponsored': [902], 'World': [905, 1823], 'Health': [906], 'Organization': [907], 'Regional': [908], 'Office': [909], 'Europe,': [911], 'set': [912, 1429], 'new': [913], 'targets': [914, 1031, 1145, 1151, 1276, 1306], 'management': [917, 1044, 1409, 2350], 'care.6': [919], 'One': [920], 'specific': [921, 938, 1144], 'goal': [922, 966, 1495], '2015': [924], 'who': [932], 'should': [940, 1337], 'transferred': [942], 'hospitals': [944], 'adequate': [946], 'capacity': [947], 'expertise': [949], 'administer': [951], 'treatments—defined': [952], 'or': [956, 1166, 1672, 1679, 1702, 2110], 'dedicated': [958, 1177], 'area.': [959], 'current': [961, 1024], 'suggests': [963], 'being': [971, 1140], 'reached.The': [972], 'Organisation': [975, 1125, 1244], 'therefore': [977], 'prepared': [978, 1083, 1240], 'Action': [982, 1927], 'Plan': [983, 1928], '(ESAP)': [984], 'years': [987], '2018': [988, 2382, 2391], '2030,': [990], 'cooperation': [992], 'Europe.7': [1001], 'ESAP': [1003, 1058, 1081, 1118, 1235, 1286, 1319, 1435], 'adheres': [1004], 'format': [1007], 'Declarations,': [1011], 'presenting': [1012], 'review': [1014, 1297, 1802], 'state': [1017, 1022], 'art,': [1020], 'services,': [1025, 1043], 'research': [1026, 1072, 1278], 'development': [1028, 1074, 1280], 'priorities,': [1029], 'series': [1034], 'domains': [1036], '(organization': [1040], 'stroke,': [1047, 1069, 1372, 2222], 'prevention,': [1048], 'rehabilitation,': [1049], 'evaluation': [1050], 'outcome,': [1053], 'assessment).': [1056], 'includes': [1059], '2': [1060], 'additional': [1061], 'domains,': [1062], 'primary': [1064, 1197], 'prevention': [1065, 1198, 1447, 2144], 'life': [1067, 1200], 'after': [1068, 1201, 1245], 'priorities': [1075, 1281], 'translational': [1077], 'research.': [1079], 'open,': [1086], 'transparent': [1087], 'process': [1088], 'involved': [1090], '>100': [1091], 'scientists': [1092], 'representatives': [1096], 'almost': [1098], 'live-streamed': [1105], 'workshop': [1107], 'held': [1109], 'Munich,': [1111], 'March': [1112], '22': [1113], '23,': [1115, 1830], '2018.': [1116], 'launched': [1120], 'Congress': [1126], 'Gothenburg': [1128], 'May': [1130], '2018,': [1131], 'document': [1137], 'currently': [1139, 1428], 'finalized.ESAP': [1141], '32': [1143, 1943], 'domains.': [1148], 'Four': [1149], 'overarching': [1150], 'identified:To': [1153], 'reduce': [1154, 1220], 'absolute': [1156], '10%.To': [1163], 'treat': [1164], '90%': [1165], 'first': [1181], 'level': [1182], 'care.To': [1184], 'plans': [1187], 'encompassing': [1190], 'entire': [1192], 'chain': [1193], 'stroke.To': [1202], 'fully': [1203], 'implement': [1204], 'multisector': [1208], 'public': [1209, 1470], 'interventions': [1211], 'promote': [1213], 'facilitate': [1215], 'healthy': [1217], 'lifestyle,': [1218], 'environmental': [1221], '(including': [1222], 'air': [1223], 'pollution),': [1224], 'socioeconomic,': [1225], 'educational': [1227], 'factors': [1228], 'risk': [1232], 'stroke.An': [1234], 'implementation': [1236, 1316, 1401], 'plan': [1237, 1443, 1478, 1498], 'having': [1246], 'assessed': [1247], 'updated': [1249], 'epidemiological': [1250, 1773], 'report': [1251], 'incidence,': [1254], 'prevalence,': [1255], 'mortality': [1257], 'receiving': [1259], 'detailed': [1260, 1442], 'reliable': [1262], 'registries': [1266], 'societies.': [1272], 'Progress': [1273], 'toward': [1274], 'laid': [1282], 'out': [1283], 'reviewed': [1289, 1312], '2021': [1291], '2024,': [1293], 'midterm': [1296], 'scheduled': [1298], '2024.': [1300], 'extent': [1302], 'which': [1304, 1324], 'achieved': [1309], '2030.Clearly,': [1314], 'big': [1322], 'challenge,': [1323], 'involves': [1325], 'financial': [1326], 'factors,': [1327], 'policy': [1331], 'issues.': [1332], 'Preventing': [1333], 'treating': [1335], 'seen': [1339], 'investment': [1342], 'society': [1345], 'favorable': [1349], 'return,': [1350], 'social': [1352], 'economical,': [1354], 'just': [1357, 1500], 'healthcare': [1362], 'sector.': [1363], 'Governmental': [1364], 'bodies': [1365], 'need': [1366, 1462], 'substantially': [1368], 'upscale': [1369], 'efforts': [1370], 'other': [1375, 1485, 1685], 'noncommunicable': [1376], 'diseases,': [1377], 'requiring': [1378], 'change': [1380], 'strategy': [1382], 'many': [1384], 'National': [1389], 'neurological': [1392], 'key': [1397], 'role': [1398], 'targets.': [1404], 'Role': [1405], 'models': [1406], 'identified': [1412], '(ie,': [1413], 'Austrian': [1414], 'Network,': [1416], 'Code': [1417], 'System': [1419], 'Catalonia),': [1421], 'registers': [1427], 'several': [1432], 'likely': [1437], 'improvement': [1445], 'any': [1453], 'geographical': [1455], 'region': [1456], 'world,': [1459], 'emphasizing': [1460], 'invest': [1464], 'proportionally': [1467], 'disease.': [1475], 'Hopefully,': [1476], 'also': [1480, 1619], 'inspiration': [1483], 'areas': [1486], 'world.': [1489], 'As': [1490], 'Larry': [1491, 1945], 'Elder': [1492, 1939], 'said,': [1493], '"A': [1494], 'without': [1496], 'wish".8DisclosuresDr': [1502], 'Consultant': [1506], 'Medtronic,': [1508], 'Stryker,': [1509], 'Commonwealth': [1511], 'Serum': [1512], 'Laboratories': [1513], 'Behring.': [1514], 'He': [1515], 'principal': [1518], 'investigator': [1519], 'SWITCH': [1522], '(Swiss': [1523], 'Trial': [1524, 1640], 'Decompressive': [1526], 'Craniectomy': [1527], 'Versus': [1528, 1544, 1578, 1641], 'Best': [1529], 'Medical': [1530], 'Treatment': [1531], 'Spontaneous': [1533], 'Supratentorial': [1534], 'Intracerebral': [1535], 'Hemorrhage': [1536], '(SWITCH):': [1537], 'Randomized': [1539], 'Controlled': [1540], 'Trial),': [1541, 1564], 'ELAN': [1542], '(Early': [1543], 'Late': [1545], 'Initiation': [1546], 'Direct': [1548], 'Oral': [1549], 'Anticoagulants': [1550], 'Post-Ischaemic': [1552], 'Patients': [1554, 1660], 'With': [1555, 1570, 1661, 1677], 'Atrial': [1556], 'Fibrillation:': [1557], 'An': [1558], 'International': [1559], 'Multicenter,': [1560], 'Randomized-Controlled,': [1561], 'Two-Arm,': [1562], 'Assessor-Blinded': [1563], 'SWIFT': [1566], 'DIRECT': [1567, 1579], 'trial': [1568, 1623, 1669, 2216], '(Solitaire': [1569], 'Intention': [1572], 'Thrombectomy': [1574, 1582], 'Plus': [1575], 'Intravenous': [1576], 't-PA': [1577], 'Solitaire': [1580], 'Stent-Retriever': [1581], 'Anterior': [1585], 'Circulation': [1586], 'Stroke).': [1587], 'Dr': [1588, 1604], 'receives': [1590, 1606], 'Honoraria': [1591], 'Data': [1593], 'Safety': [1595], 'Monitoring': [1596], 'Board': [1597], 'work': [1598], 'Astra': [1600], 'Zeneca': [1601], 'Bayer.': [1603], 'Advisory': [1607], 'boards': [1608], 'speaker': [1610], 'fees': [1611], 'Bayer,': [1613], 'Boehringer': [1614], 'Ingelheim,': [1615], 'BMS-Pfizer,': [1616], 'Ever-Neuropharma.': [1617], 'She': [1618], 'participated': [1620], 'Brainsgate': [1625], 'NAVIGATE-ESUS': [1629], '(New': [1630], 'Approach': [1631], 'Rivaroxaban': [1632], 'Inhibition': [1633], 'Factor': [1635], 'Xa': [1636], 'Global': [1639], 'ASA': [1642], 'Prevent': [1644], 'Embolism': [1645], 'Embolic': [1647, 1662], 'Undetermined': [1650, 1665], 'Source),': [1651, 1666], 'RESPECT-ESUS': [1652], '(Dabigatran': [1653], 'Etexilate': [1654], 'Secondary': [1656], 'Prevention': [1658], 'SOCRATES': [1668], '(Acute': [1670], 'Transient': [1673], 'Ischemic': [1674], 'Attack': [1675], 'Treated': [1676], 'Aspirin': [1678], 'Ticagrelor': [1680], 'Patient': [1682], 'Outcomes).': [1683], 'author': [1686], 'reports': [1687], 'conflicts.FootnotesThe': [1689], 'opinions': [1690], 'expressed': [1691], 'article': [1694], 'necessarily': [1697], 'those': [1698], 'editors': [1701], 'American': [1705, 2383], 'Heart': [1706, 1753, 1776, 2370, 2384], 'Association.Correspondence': [1707], 'urs.[email': [1729], 'protected]chReferences1.': [1730], 'Wilkins': [1731], 'E,': [1732, 2075, 2085, 2087], 'Wilson': [1733, 1759], 'L,': [1734, 1760, 1994, 2008, 2014, 2071, 2172, 2328], 'Wickramasinghe': [1735, 1763], 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{'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 4}], 'updated_date': '2024-09-16T21:31:21.229619', 'created_date': '2018-09-07'}