Title: Are TSH normal reference ranges adequate for pregnant women?
Abstract: A) PREANALYTICAL FACTORS Gestational age – The changes in thyroid function tests according to gestational age have been elegantly shown in a study of 13,599 nulliparous women evaluated at 1 week intervals from the 6th week to term. The study documented that TSH falls to minimal levels during the 10th week, followed by a progressive increase until term, with its value in the 10th week being half the value observed at the beginning of pregnancy. Studies on other populations (Finnish [...]