Title: Splenic artery ligation in experimental hypersplenism.
Abstract: The effects of splenic artery ligation (SAL) were examined in Sprague-Dawley rats with methyl-cellulose-induced hypersplenism. When performed close to the splenic hilium, SAL effectively reduced functioning splenic mass and raised peripheral counts of leukocytes and platelets, a response similar to that following total splenectomy. In hypersplenism, therefore, a satisfactory hematologic response may not necessary require total ablation of the spleen but merely substantial reduction of functioning splenic tissue.
Publication Year: 1976
Publication Date: 1976-11-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 9
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