Title: Relation of risk factors to coronary artery stenosis severity in coronary atherosclerotic heart disease
Abstract: :Objective To study therelationship of the risk factors to the coronary artery stenosis severity in coronaryatherosclerotic heart disease (CAD). Methods 286 CAD patients, 206 males and 80females,aged 61.6, underwent coronary angiography and then were divided into 3 groups according toits results: Group A with single vessel lesion, Group B with double vessel lesions, andGroup C with triple/left main vessel lesions. Peripheral blood samples were collected tomeasure the levels of uric acid, C reactive protein, cholesterol, low density lipoproteincholesterol (LDL-C), high density lipoprotein cholesterol, and triglyceride. Spearmancorrelation analysis and multiple linear regression were used to analyze the relationshipbetween the risk factors including age, bodyweight, and blood lipids and uric acid.Results There was significant difference among the three groups at age and LDL-C ( both P < 0.05 ). Age and LDL-C of Group C [ (62 ± 10), ( 3.0 ± 0.7 )mmol/L] were significantly higher than those of Group A [ ( 59 ±11 ), (2.8 ± 0.6 )mmol/L, both P < 0.05 ]. Age ( r = 0. 163 )and LDL-C ( r = 0. 149 ) were significantly associated with coronary artery stenosisseverity ( both P < 0.05 ). Conclusion The severity of coronary artery stenosis is affected by ageand LDL-C. Triple/left main vessel lesions are likely to be seen in the patients witholder age and higher blood level of LDL-C.
Key words:
Coronary stenosis; Risk factors; Correlation
Publication Year: 2008
Publication Date: 2008-05-13
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 2
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