Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2398904413', 'doi': None, 'title': '[Relationship between abnormal expression of beta-catenin in gastric carcinoma and survival].', 'display_name': '[Relationship between abnormal expression of beta-catenin in gastric carcinoma and survival].', 'publication_year': 2002, 'publication_date': '2002-05-01', 'ids': {'openalex': 'https://openalex.org/W2398904413', 'mag': '2398904413', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12452049'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12452049', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5021503189', 'display_name': 'Yongning Zhou', 'orcid': 'https://orcid.org/0000-0002-7304-929X'}, 'institutions': [{'id': 'https://openalex.org/I76214153', 'display_name': 'Lanzhou University', 'ror': 'https://ror.org/01mkqqe32', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76214153']}, {'id': 'https://openalex.org/I4210163492', 'display_name': 'First Hospital of Lanzhou University', 'ror': 'https://ror.org/05d2xpa49', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210163492']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yong-ning Zhou', 'raw_affiliation_strings': ['Department of Gastroenterology, First Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000, P. R. China. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'Department of Gastroenterology, First Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000, P. R. China. [email protected]', 'institution_ids': ['https://openalex.org/I76214153', 'https://openalex.org/I4210163492']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5106387597', 'display_name': 'Min Li', 'orcid': 'https://orcid.org/0000-0002-1310-2503'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Min Li', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.365893, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 64, 'max': 68}, 'biblio': {'volume': '21', 'issue': '5', 'first_page': '536', 'last_page': '40'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.965, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.965, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9647, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9404, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/beta-catenin', 'display_name': 'Beta-catenin', 'score': 0.599943}, {'id': 'https://openalex.org/keywords/beta', 'display_name': 'BETA (programming language)', 'score': 0.4135387}], 'concepts': [{'id': 'https://openalex.org/C149402561', 'wikidata': 'https://www.wikidata.org/wiki/Q24776048', 'display_name': 'Cadherin', 'level': 3, 'score': 0.6964398}, {'id': 'https://openalex.org/C30145163', 'wikidata': 'https://www.wikidata.org/wiki/Q384104', 'display_name': 'Catenin', 'level': 4, 'score': 0.6949051}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.681284}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.60031444}, {'id': 'https://openalex.org/C2779324961', 'wikidata': 'https://www.wikidata.org/wiki/Q1634046', 'display_name': 'Beta-catenin', 'level': 4, 'score': 0.599943}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.56971985}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.4792333}, {'id': 'https://openalex.org/C74864618', 'wikidata': 'https://www.wikidata.org/wiki/Q2332446', 'display_name': 'Staining', 'level': 2, 'score': 0.4390452}, {'id': 'https://openalex.org/C2780849966', 'wikidata': 'https://www.wikidata.org/wiki/Q170758', 'display_name': 'Lymph node', 'level': 2, 'score': 0.41539484}, {'id': 'https://openalex.org/C2776174256', 'wikidata': 'https://www.wikidata.org/wiki/Q830842', 'display_name': 'BETA (programming language)', 'level': 2, 'score': 0.4135387}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.41113722}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3698408}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.35592926}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.32346484}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.28845984}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.22734183}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.08470094}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.053497195}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D015996', 'descriptor_name': 'Survival Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12452049', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'No poverty', 'id': 'https://metadata.un.org/sdg/1', 'score': 0.62}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3194327487', 'https://openalex.org/W318955610', 'https://openalex.org/W3025709098', 'https://openalex.org/W2386508889', 'https://openalex.org/W2380363485', 'https://openalex.org/W2330151937', 'https://openalex.org/W2148723211', 'https://openalex.org/W2113154154', 'https://openalex.org/W2067703867', 'https://openalex.org/W2015985945'], 'abstract_inverted_index': {'Altered': [0], 'cell': [1], 'adhesion': [2, 20], 'has': [3], 'a': [4, 142, 239], 'critical': [5], 'role': [6], 'in': [7, 48, 68, 81, 94, 127, 132, 162, 176, 200, 224], 'the': [8, 16, 44, 54, 114, 219], 'development': [9], 'of': [10, 18, 46, 62, 75, 88, 98, 104, 113, 151, 206, 209, 218], 'epithelial': [11], 'cancers.': [12], 'E-cadherin': [13, 65, 78, 91, 122], 'act': [14], 'on': [15], 'maintenance': [17], 'cell-cell': [19], 'and': [21, 36, 51, 59, 64, 77, 90, 96, 121, 149, 171, 187], 'its': [22], 'function': [23], 'was': [24, 40, 66, 79, 92, 141, 159, 198], 'thought': [25], 'to': [26, 42, 52, 102], 'be': [27, 238], 'regulated': [28], 'by': [29], 'associated': [30], 'cytoplasmic': [31], 'proteins,': [32], 'such': [33], 'as': [34], 'alpha-catenin': [35], 'beta-catenin.': [37], 'This': [38], 'study': [39], 'designed': [41], 'examine': [43], 'expression': [45, 74, 87, 148, 158, 205, 217], 'beta-catenin': [47, 63, 76, 89, 120, 147, 157, 236], 'gastric': [49, 72, 85, 225], 'carcinoma': [50], 'determine': [53], 'relationship': [55], 'between': [56, 145], 'tumor': [57, 130], 'characteristics': [58], 'survival.Immunohistochemical': [60], 'staining': [61, 123], 'performed': [67, 80], '148': [69, 82], 'patients': [70, 83], 'with': [71, 84, 164, 230], 'carcinoma.Abnormal': [73, 86], 'demonstrated': [93], '43.2%': [95], '44.6%': [97], 'tumors': [99, 105, 135, 163, 177, 201], 'respectively.': [100], 'Up': [101], '63%': [103], 'stained': [106], 'abnormally': [107], 'for': [108], 'one': [109], 'or': [110, 212], 'two': [111], 'components': [112], 'cadherin-catenin': [115], 'complex': [116, 221], '(beta-catenin,': [117], 'E-cadherin).': [118], 'Abnormal': [119], 'occurred': [124], 'more': [125, 160], 'frequently': [126, 223], 'poor': [128, 231], 'differentiated': [129, 134], 'than': [131, 175], 'good': [133], '(P': [136, 184, 192, 214], '<': [137, 153, 185, 193, 215], '0.005,': [138], 'respectively).': [139], 'There': [140], 'significant': [143], 'correlation': [144, 229], 'abnormal': [146, 156, 235], 'depth': [150], 'invasion(P': [152], '0.025).': [154], 'Moreover,': [155], 'frequent': [161], 'positive': [165], 'lymph': [166, 179], 'node': [167, 180], 'metastasis': [168, 181, 189], '(45/84,': [169], '53.6%)': [170], 'distance': [172, 188], 'metastasis(21/31,': [173], '67.7%)': [174], 'without': [178], '(19/64,': [182], '29.7%)': [183], '0.005)': [186], '(43/117,': [190], '36.8%)': [191], '0.005).': [194], 'A': [195], 'survival': [196, 232], 'advantage': [197], 'noted': [199], 'retaining': [202], 'normal': [203], 'membranous': [204], 'beta-catenin,': [207], 'independent': [208], 'type,': [210], 'grade,': [211], 'stage': [213], '0.005).Abnormal': [216], 'E-cadherin-catenin': [220], 'occurs': [222], 'carcinoma.': [226], 'The': [227], 'close': [228], 'suggests': [233], 'that': [234], 'may': [237], 'useful': [240], 'prognostic': [241], 'marker.': [242]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2398904413', 'counts_by_year': [{'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-11T03:47:16.741416', 'created_date': '2016-06-24'}