Publication Information

{'id': 'https://openalex.org/W2394386219', 'doi': None, 'title': 'Significance of expression of bcl-2 mRNA and bax mRNA in arsenic trioxide-induced apoptosis of hepatocellular carcinoma cells', 'display_name': 'Significance of expression of bcl-2 mRNA and bax mRNA in arsenic trioxide-induced apoptosis of hepatocellular carcinoma cells', 'publication_year': 2003, 'publication_date': '2003-01-01', 'ids': {'openalex': 'https://openalex.org/W2394386219', 'mag': '2394386219'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGD200304007.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764921924', 'display_name': 'Zhonghua gan-dan waike zazhi', 'issn_l': '1007-8118', 'issn': ['1007-8118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100426831', 'display_name': 'Jiangtao Li', 'orcid': 'https://orcid.org/0000-0002-4293-0287'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'LI Jiangtao', 'raw_affiliation_strings': ['*, SOU Qingjia, LIU Yingbin, et al'], 'affiliations': [{'raw_affiliation_string': '*, SOU Qingjia, LIU Yingbin, et al', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5100426831'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 59}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11559', 'display_name': 'Role of Retinoic Acid in Biological Processes', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11559', 'display_name': 'Role of Retinoic Acid in Biological Processes', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9413, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T14099', 'display_name': 'Recent Advances in Triazine Chemistry', 'score': 0.9385, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arsenic-trioxide', 'display_name': 'Arsenic trioxide', 'score': 0.94636273}, {'id': 'https://openalex.org/keywords/dna-laddering', 'display_name': 'DNA laddering', 'score': 0.5921616}, {'id': 'https://openalex.org/keywords/bcl-2-family', 'display_name': 'Bcl-2 Family', 'score': 0.486532}], 'concepts': [{'id': 'https://openalex.org/C2780386689', 'wikidata': 'https://www.wikidata.org/wiki/Q7739', 'display_name': 'Arsenic trioxide', 'level': 3, 'score': 0.94636273}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.83010256}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.7210223}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.69005036}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.6077823}, {'id': 'https://openalex.org/C155878803', 'wikidata': 'https://www.wikidata.org/wiki/Q5205755', 'display_name': 'DNA laddering', 'level': 5, 'score': 0.5921616}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.53813714}, {'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.52756846}, {'id': 'https://openalex.org/C196795494', 'wikidata': 'https://www.wikidata.org/wiki/Q1624817', 'display_name': 'TUNEL assay', 'level': 3, 'score': 0.49159154}, {'id': 'https://openalex.org/C4692481', 'wikidata': 'https://www.wikidata.org/wiki/Q169526', 'display_name': 'Reverse transcription polymerase chain reaction', 'level': 4, 'score': 0.4533434}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37325007}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.29404727}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.21641427}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.18352914}, {'id': 'https://openalex.org/C43759708', 'wikidata': 'https://www.wikidata.org/wiki/Q3749256', 'display_name': 'DNA fragmentation', 'level': 4, 'score': 0.172304}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1349113}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGD200304007.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764921924', 'display_name': 'Zhonghua gan-dan waike zazhi', 'issn_l': '1007-8118', 'issn': ['1007-8118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3148256673', 'https://openalex.org/W3032237750', 'https://openalex.org/W3031715460', 'https://openalex.org/W3031342630', 'https://openalex.org/W2978434767', 'https://openalex.org/W2616894454', 'https://openalex.org/W2393375070', 'https://openalex.org/W2386184910', 'https://openalex.org/W2385387834', 'https://openalex.org/W2382456530', 'https://openalex.org/W2381427931', 'https://openalex.org/W2381191045', 'https://openalex.org/W2367404456', 'https://openalex.org/W2365372884', 'https://openalex.org/W2248992977', 'https://openalex.org/W2100394422', 'https://openalex.org/W2030520840', 'https://openalex.org/W1993558704', 'https://openalex.org/W151159871', 'https://openalex.org/W1500440562'], 'abstract_inverted_index': {'ObjectiveTo': [0], 'explore': [1], 'of': [2, 4, 6, 16, 51, 85, 99, 101, 107, 123, 130], 'significance': [3], 'expression': [5, 50, 84, 100, 126, 133], 'bcl-2': [7, 52, 86, 131], 'mRNA': [8, 11, 53, 56, 87, 103, 125, 132], 'and': [9, 45, 54, 95], 'bax': [10, 55, 102, 124], 'in': [12, 72, 78, 91, 118], 'arsenic': [13, 30], 'trioxide-induced': [14], 'apoptosis': [15, 36, 68, 115], 'hepatocellular': [17], 'carcinoma': [18], '(HCC)': [19], 'cells.': [20], 'MethodsAfter': [21], 'human': [22], 'HCC': [23], 'cell': [24, 120], 'line': [25], 'bel-7402': [26, 119], 'was': [27, 37, 57, 69], 'treated': [28], 'with': [29, 39, 59, 105], 'trioxide': [31], 'at': [32], 'various': [33], 'concentrations,': [34], 'the': [35, 49, 92], 'detected': [38, 71], 'transmission': [40], 'electron': [41], 'microscopy,': [42], 'flow': [43], 'cytometry': [44], 'DNA': [46], 'laddering.': [47], 'Meanwhile,': [48], 'determined': [58], 'semiquantitative': [60], 'reverse': [61], 'transcription': [62], 'polymerase': [63], 'chain': [64], 'reaction': [65], '(RT-PCR).': [66], 'ResultsCell': [67], 'not': [70, 89, 128], '0.5': [73], 'μmol/L': [74, 80], 'As_2O_3': [75, 81, 108, 117], 'group': [76, 94], 'but': [77, 127], '8': [79], 'group.': [82, 97], 'The': [83], 'were': [88], 'seen': [90], 'control': [93], 'drug-treated': [96], 'Enhancement': [98, 122], 'along': [104], 'increase': [106], 'concentration.': [109], 'ConclusionsProliferation': [110], 'is': [111, 134], 'inhibited': [112], 'via': [113], 'inducing': [114], 'by': [116], 'line.': [121], 'that': [129], 'related': [135], 'to': [136], 'this': [137], 'process.': [138]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2394386219', 'counts_by_year': [], 'updated_date': '2024-09-18T08:09:15.400061', 'created_date': '2016-06-24'}