Title: The Therapeutic Drug Monitoring of Digoxin in Children and the Analysis of Influential Factor
Abstract: Objective:To observe the importance of blood concentration monitoring in more individualized and rationalized administration of Digoxin.Methods:We performed the blood concentration monitoring of Digoxin by using chemiluminescent immunoassay and analyzed the results.Results:Among 161 child patients,there were 79 cases within the effective blood concentration(0.8~2.0 ng/mL),accounted for 49.1%.There were 74 cases below 0.8 ng/mL,accounted for 46.0%,and 8 cases higher than 2.0 ng/mL accounted for 4.9%.Conclusions:We should consider the children's pharmacodynamics,pharmacokinetics,blood concentration monitoring and clinical observation to get the effect,rational and safe result and prevent the drug poisoning of digoxin.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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