Title: Contrast-enhanced ultrasound-guided microwave tissue coagulation therapy for hepatic trauma of grade I to III: experimental study
Abstract: Objective To study the value of contrast-enhanced ultrasound-guided microwave tissue coagulation (MTC) therapy for hepatic trauma of gradeⅠto Ⅲ. Methods Hepatic trauma of grade Ⅰ, Ⅱ and Ⅲ with active hemorrhage were created respectively in 10 heparinized porcine livers. MTC was performed under the guidance of contrast-enhanced ultrasound. Two hours after MTC, the therapeutic region was observed again and contrast-enhanced ultrasound and pathologic examination were performed to assess the effect of MTC. Results All hepatic trauma were treated successfully with MTC. The bleeding time in traumatic regions of grade Ⅱ and Ⅲ ([192.0±108.0] s, [443.4±63.5] s) were longer than that in grade Ⅰ ([48.3±33.3] s)(P0.01) and the blood loss ([24.8±6.5] g and [47.8±10.5] g) were also larger than that in grade Ⅰ ([6.6±4.3] g)(P0.01). Two hours after MTC no hemorrhage and hematoma was observed on the surface of therapeutic region. Contrast-enhanced ultrasound showed that the therapeutic region was not enhanced in spite of a few small regular vascular enhancement at the periphery in 9 trauma of gradeⅡand 5 trauma of grade Ⅲ. Pathologic examination showed the hepatocytes were degenerative obviously in all therapeutic region but vessels were degenerative only in the central area. Conclusion MTC therapy is effective in treating hepatic trauma of grade Ⅰ to Ⅲ which may be an auxiliary method to surgery.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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