Title: Observation of High Sensitive C-reactive Protein Level in Type 2 Diabetes Serum and Its Correlation with Microalbuminuria
Abstract: Objective To explore the changes of high sensitive C-reactive protein (hs-CRP) level in type 2 diabetes serum and its correlation with microalbuminuria (MAU). Methods 160 patients with type 2 diabetes mellitus were divided into 2 groups according to urine albumin excretion rate (UAEA), normal albuminuria group and microalbuminuria group. Fasting plasma glucose (FPG) and hs-CRP were detected in all patients and were compared with those obtained from 100 healthy individuals. Result hs-CRP in type 2 diabetes was significantly higher than that of healthy individuals (P0.01). When two groups of type 2 diabetes were compared, hs-CRP in the microalbuminuria group was significantly higher than that in normal albuminuria group (P0.05). Conclusion Increased level of hs-CRP may correlate with type 2 diabetes and its complications. Microalbuminuria is a risk factor for cardiovascular complication. Chronic inflammation, as indicated by increased level of hs-CRP, may trigger microalbuminuria and cardiovascular complications.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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