Title: Comparison of the effect of antibiotics administration in perioperative and postoperative orthopaedic surgery
Abstract: OBJECTIVE Objective to investigate the proper administration of antibiotics in orthopaedic surgery periaperatively with aim to effectively prevent postoperative infection(PI). METHOD In perioperative administration(PA) group ,patients administered antibiotics intravenously half an hour before operation or intramuscularly two hours before operation,when operation time lasted more than 3 4h,another dose was given to the patients,the postoperative administration of antibiotics was less than 72h.In control group,patients received antibiotics intramuscularly or continuous intravenously from 3 days to 7 days after operation.RESULTS In PA group ,5 of 586 patients(0.853%) suffered from PI,none had adverse reaction.Of 586 patients,312 with sterile operation were not infected after operation .In the control group ,18 of 543 patients(3.315%) suffered from PI,one of 18 patients was infected after sterile operation and another one had incision infection combined with aluet mould infection.CONCLUSION The proper administration of antibiotics in orthopaedic surgery perioperatively shoud be a safe and effedire way to prevent orthopaedic PI.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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