Title: Efficacy of budesonide combined with compound ipratropium bromide aerosol in the treatment of bronchiolitis
Abstract: Objective To explore the efficacy and side effects of budesonide joint combined with ipratropium bromide aerosol in the treatment of bronchiolitis.Methods Ninety children with bronchiolitis were randomly divided into treatment group(n=45) and control group(n=45).Both of the two groups received conventional treatment of anti-infection,cough and phlegm.The control group,on the basis of conventional treatment,received methylprednisolone,while the treatment group was administered budesonide combined with compound ipratropium bromide inhalation solution.Children received continuous treatment for 7 days.The overall efficacy between the two groups,the symptoms and signs of remission or disappearance time,differences in the length of hospital stay,and side effects were observed.Results The total efficacy rate showed no significant differences between the two groups.Clinical symptoms,signs of remission or disappearance time and the length of hospital stay in the treatment group were significantly shorter than those in the control group.The difference was statistically significant.There were 2 children with irritability,and one child with diarrhea in the control group.There were no obvious adverse reactions in the treatment group.Conclusion Budesonide suspension combined with compound ipratropium solution aerosol inhalation is effective in treating children with bronchiolitis.It can effectively reduce the symptoms and signs of remission or the disappearance time,accelerate the improvement or recovery of the children,shorten hospital stay without increasing the incidence of adverse reactions.It is worthy of wide clinical application,especially in primary-level hospitals.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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