Title: Long-term effect of penetrating keratoplasty and pars plana vitrectomy under temporary keratoprosthesis on severe traumatic ocular injury of anterior and posterior segment
Abstract: Objective To evaluate the long-term effect of penetrating keratoplasty (PKP) and pars plana vitrectomy (PPV) under temporary keratoprosthesis on severe traumatic ocular injury of anterior and posterior segment. Methods Combined PKP and PPV under temporary keratoprosthesis were performed in 11 eyes of 11 male patients (6 adults, 5 children), aged from 7 to 46. Visual acuity, graft transparency, intraocular pressure and retinal anatomic status were examined during follow-up. Results The follow-up period ranged from 4 to 68 months with a mean of 24.6 months. Five adult patients (5 eyes, 45.5%) were successfully cured. Of the five eyes, visual acuity of one eye reached hand motion, two eyes 0.05, the other two eyes 0.08 and 0.2 respectively. Intraocular pressure as high as 25 mmHg in one eye was successfully managed with topical application of 0.5% timolol. Intraocular pressure of the other 4 eyes were in normal range. Six atrophic eyes developed in 6 patients (54.5%), including 5 children below 12 years old, and one adult with secondary glaucoma treated with transscleral cyclophotocoagulation. Conclusion Combined PKP and PPV under temporary keratoprosthesis is safe and effective for severe injury of anterior and posterior segment caused by ocular trauma. The main cause of failure is the severity of eye injuries, and traumatic eyes in children have a much poorer outcome after the combined surgery than in adult patients.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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