Title: Clinical and imageological analysis of the skull base erosion in nasopharyngeal carcinoma
Abstract: Objective The purpose of this work was to investigate and analyze the clinical and imageological features of skull base erosion in nasopharyngeal carcinoma(NPC). Methods Sixty-seven NPC patients proved by pathology were retrospectively reviewed,which underwent both CT and MRI plain plus enhancement scan. Scan slices were done from oral pharynx (lower border of second cervical vertebra) to suprasellar cistern. Results 1) 52 patients with skull base erosion were found on MRI,and only 35 on CT. The display percentage had statistical difference(x2=9.47,P=0.02). 2) Skull base erosion on CT scan was mostly bone destruction,however,not only bone destruction but also tumor crossing skull base structure could be seen on MRI scan. 3) The incidence of headache was 84.6%(44/52),cranial nerve palsy 69.2%(36/52),headache or cranial nerve palsy in skull base erosion 57.7%(30/52). Conclusions MRI is superior to CT in demonstrating both skull base and soft tissue abnormality. Headache and cranial nerve palsy are primary characteristic of the skull base erosion in nasopharyngeal carcijoma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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