Title: Efficacy analysis on medical imaging-guided ethanol injection combined with microwave ablation in patients with recurrent malignant schwannoma
Abstract: Objective To analyze the therapeutic effect of medical imaging-guided intratumoral injection of ethanol combined with microwave for the treatment of recurrent malignant schwannoma.Methods Eight patients with recurrent malignant schwannoma who could not be re-resected were injected with ethanol intratumorally under CT or ultrasound and then combined with microwave ablation.The improved clinical symptoms after treatment,the local tumor control effect and the long-term efficacy were observed.Results After treatment,the clinical symptoms in 8 patients were improved by varying degrees.The Karnofsky score was raised from 67.52 ± 10.50 before treatment to 85.33 ± 14.32(P = 0.013).Enhanced CT scan showed no tumor enhancement and the volume was gradually reduced from(34.65 ± 9.27) cm 3 before treatment to(24.51 ± 6.32) cm 3(P = 0.011) after six-month follow-up.The overall follow-up was 24 to 62 months.Six cases were surviving and 2 died and no obvious treatment-related complications were discovered.Conclusion Ethanol injection combined with microwave ablation for the treatment of malignant schwannoma shows minimal invasion,slight complications and significant local efficacy and can be used as a supplementary treatment for patients with recurrent malignant schwannoma.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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