Title: Research progress of chemokine receptor antagonist plerixafor
Abstract: Plerixafor is an antagonist of CXC chemokine receptor type 4(CXCR4),a receptor for stromal cell derived factor-1(SDF-1).It disrupts binding of SDF-1 to CXCR4 by competing binding site,thus blocking the physiological function of SDF-1/CXCR4 axis.This review summarizes the pharmacology and the clinical research of plerixafor.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot