Title: Clinical observation of the effect of TACE combined with three dimensional conformal radiotherapy on patients with advanced hepatocellular carcinoma
Abstract: Objective To investigate the clinical effects of transcatheter arterial chemoembolization(TACE) combined with three dimensional conformal radiotherapy(3-DCRT)on patients with advanced hepatocellular carcinoma.Methods A total of 87 patients with advanced hepatocellular carcinoma were randomly divided into TACE/3-DCRT group(n=45)and TACE group(n=42).The patients in TACE/3-DCRT group were treated first with TACE and then 3-DCRT,the dose was 2.6~3.2Gy each time,and the total dose was 48~60Gy.The patients in TACE group were given TACE only.Results The total response(CR+PR) were 86.7% in TACE/3-DCRT group,much higher than 66.7% in TACE group(P0.05);The 1,2,3-year survival rates were 73.3%,53.3%,35.6% and 59.5%,31.0%,14.3%,respectively in the two groups.Conclusions TACE combined with 3-DCRT is more effective than TACE only,and the side effects are tolerated.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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