Title: A clinical observation of aminophylline in preventing the apnea of very low birth weight infant
Abstract: Objective: To explore the clinical efficacy of aminophylline in preventing the apnea of very low birth weight infant. Methods: 126 premature infants of very low birth weight were randomly divided into control group and prevent group,each with 63 infants.The infants of prevent group were treated preventively with aminophylline before they apnea phenomenon happened to them,and compare them with the control group at the same time.Results: Originating rate of apnea: After born 10 days the infants of prevent group was 11.11%,the control group was 49.29%(χ~2=19.93,P0.001).At the time of gestational age of 36 weeks,the originating rate of apnea of the prevent group was 14.29% and that of the control one was 58.73%(χ~2=24.96,P0.001).The differences between these two groups have statistic significance.At the aspect of inhale oxygen time,time that weight added to 2 kg and average days in hospital,and all the differences have statistic significance(t=10.89,P0.001;t=2.04,P0.05;t=3.28,P0.05).Conclusions: The application of aminophylline to very low birth weight infant can reduce the frequency of apnea,reduce the inhale oxygen time,help put on weight and curtail time in hospital.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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