Title: Early changes of electroretinogram in company with rat development
Abstract: Objective To investigate the early changes of electroretinogram(ERG)in normal SD rats before openning their eyes in company with retinal development.Methods Rod-ERG,maximum-ERG(Max-ERG),oscillatory potentials,Cone-ERG and Flick-ERG of 30 normal SD rats(30 eyes)at the age of postnatal 9 days(P9d),P10d,P11d,P12d and P13d,respectively.Results The Flick-ERG could be recorded as early as P9d,the latency was(34.20±7.10)ms,and the amplitude was(0.59±0.16)μV.Max-ERG of a-wave and the oscillatory potentials of O1-wave were observed at P10.The latency of a-wave was(23.30±3.90)ms,and the amplitude was(1.58±0.58)μV;The latency of O1-wave was(18.60±3.00)ms,and the amplitude was(0.53±0.22)μV.The Rod-ERG,Max-ERG of b-wave and Cone-ERG could not be recorded before opening eyes.Conclusion This experiment initially explores the record way of ERG and its development before opening eyes,which provides some evidence for further study of wave origin of ERG.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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