Title: Solvent dependent colorimetric, ratiometric dual sensor for copper and fluoride ions: Real sample analysis, cytotoxicity and computational studies
Abstract: A novel colorimetric chemosensor based on terephthalic acid and pyridine aldehyde moiety was designed to detect Cu2+/F− ions in aqueous and DMSO solutions at physiological pH conditions with the detection limit of 0.25 μM and 3 μM for Cu2+/F− ions respectively. The probe was found to be highly selective to sense F− ion rather than CH3COO− and H2PO4− ions. Interestingly, the probe behaved as a promising receptor by detecting F− ions even in ordinary tap water through distinct colour change. Moreover, the chemosensor showed lower cytotoxicity against AGS cancer cells and thus found to be biologically friendly. The reversibility of probe-F− binding was investigated using HCl in UV–vis experiment. The binding mechanism of chemosensor to Cu2+/F− ions was elucidated based on the UV–vis spectroscopy, NMR, ESI-Mass spectroscopy and cyclic voltammogram techniques. Furthermore, theoretical investigation was carried out using Gaussian 09 program.
Publication Year: 2016
Publication Date: 2016-04-29
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 24
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot