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240, 278, 286, 290, 293, 316, 356, 399, 408, 431, 457, 474, 496, 506, 509, 679, 701, 728, 764, 819, 929, 1016, 1159], 'smooth': [227, 469], 'muscle': [228, 348, 470, 821, 852], 'cell': [229, 349, 471, 722, 746], 'apoptosis': [230, 310, 350, 442, 472, 490, 723, 747, 762, 833], 'along': [231], 'with': [232, 246, 252, 771, 912], 'changes': [233, 342, 564], 'cellular': [235, 588], 'extracellular': [237, 344], 'components': [238, 320, 455, 567], 'ureteropelvic': [241, 256, 281, 295, 359, 369, 380, 417, 460, 500, 530, 551, 574, 659, 686, 873], 'junction': [242, 257, 282, 360, 381, 461, 501, 531, 552, 575, 660, 687, 741, 874], '23': [244], 'patients': [245, 413], 'unilateral': [247], 'obstruction': [248, 361, 502, 661, 699], 'compared': [250, 365, 414], 'them': [251], '25': [253], 'autopsies': [254], 'from': [255, 269], 'regions': [258], 'age': [260, 298], 'matched': [261, 299], 'cadavers.': [262], 'Materials': [263], 'Methods:': [265], 'Tissue': [266, 620], 'specimens': [267], 'obtained': [268], 'pyeloplasty': [270], 'were': [271, 301, 336, 404, 466], 'divided': [272], 'into': [273], '3': [274, 561], 'sections—renal': [275], 'pelvis': [276, 384, 681, 931], 'above': [277], 'obstruction,': [279], 'obstructed': [280, 287, 379, 409], 'ureter': [284, 389, 702, 933], 'below': [285], 'region.': [288], 'For': [289], 'control': [291], 'group': [292], 'normal': [294, 367, 416, 608], 'junctions': [296, 370], 'infants': [300], 'autopsied.': [302], 'In': [303, 810], 'paraffin': [304], 'embedded': [305], 'sections': [306, 377, 615], 'we': [307], 'determined': [308], 'myocyte': [309, 441, 489], 'index': [311, 351], '(using': [312, 324], 'TUNEL': [313], 'assay),': [314], 'amount': [317, 452], 'muscular': [319, 402, 454], 'nerve': [322, 396, 447, 522], 'terminals': [323, 397], 'image': [325], 'analysis': [326, 612], 'techniques': [327], 'after': [328, 682, 858], 'immunohistochemical': [329], 'staining).': [330], 'The': [331, 393, 1090], 'collagen': [332, 420, 477, 566, 604, 885, 906], 'elastin': [334, 479, 606], 'fibers': [335, 421], 'specifically': [337], 'stained': [338], 'for': [339, 488, 508, 813, 871, 1053], 'evaluation': [340], 'matrix.': [345], 'Results:': [346], 'Smooth': [347, 980, 1012], 'was': [352, 437], 'significantly': [353, 405, 424], 'increased': [354], 'at': [355, 407, 430, 456], 'site': [357, 432, 458], '(5.68': [362], '±': [363, 372, 386, 391], '0.18)': [364], 'autopsied': [368], '(3.60': [371], '0.11)': [373], '2': [375, 540], 'other': [376], 'complex': [382], '(renal': [383], '4.73': [385], '0.16,': [387], '3.97': [390], '0.16).': [392], 'number': [394, 445], 'percentage': [400, 475], 'component': [403], 'lower': [406], 'segments': [410], 'affected': [412], 'junctions.': [418], 'Meanwhile,': [419], 'formed': [422], 'higher': [425], 'proportion': [426], 'ureteral': [428, 767], 'wall': [429], 'obstruction.': [434, 462, 532, 553, 576, 688, 875], 'Interestingly,': [435], 'there': [436], 'negative': [438], 'correlation': [439, 743], 'between': [440, 468], 'indices': [443], 'endings': [448], 'as': [449, 451], 'well': [450], 'However,': [463], 'positive': [464], 'correlations': [465], 'found': [467], 'fibers.': [480], 'Conclusions:': [481], 'Our': [482], 'findings': [483], 'suggest': [484], 'an': [485], 'important': [486], 'role': [487], 'defective': [492], 'neural': [493], 'development': [494], 'pathogenesis': [497, 765], 'congenital': [499, 550, 573], 'that': [503, 782], 'could': [504], 'pave': [505], 'road': [507], 'emergence': [510], 'new': [512], 'therapeutic': [513], 'modalities.': [514], 'References': [515], '1': [516], ':': [517, 541, 562, 585, 600, 627, 651, 674, 697, 720, 739, 760, 780, 809, 831, 850, 868, 882, 903, 925], 'Abnormal': [518], 'innervation': [519], 'altered': [521], 'growth': [523], 'factor': [524], 'messenger': [525, 886], 'ribonucleic': [526], 'acid': [527], 'expression': [528, 543, 677], 'J': [533, 554, 577, 666, 689, 713, 752, 801, 860, 895, 917, 937], 'Urol1995;': [534], '154:': [535], '679.': [536], 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'staining': [629], 'collagens': [631], 'type': [632], 'I,': [633], 'II': [634], 'III': [636, 884], 'sirius': [638], 'red': [639], 'polarization': [641], 'Arch': [643], 'Histol': [644], 'Jpn1978;': [645], '41:': [646], '267.': [647], '7': [650], 'structure': [653], 'ultrastructure.': [655], 'Part': [656], 'II.': [657], 'primary': [663], 'megaureter.': [665], 'Urol1976;': [667], '116:': [668], '725.': [669], '8': [673], 'TGF-beta': [675], 'mRNA': [676], 'renal': [680, 704, 745, 750, 930], 'experimental': [683], 'clinical': [685], 'Urol1996;': [690], '156:': [691], '261.': [692], '9': [696], 'Functional': [698], 'pelvis.': [705], 'A': [706, 971, 1047], 'histological': [707], 'electron': [709], 'microscopic': [710], 'study.': [711], 'Br': [712, 916], 'Urol1978;': [714], '50:': [715], '145.': [716], '10': [719], 'Renal': [721], 'chronic': [725], 'uropathy:': [727], 'roles': [729], 'caspases.': [731], 'Kidney': [732], 'Int2001;': [733], '60:': [734], '924.': [735], '11': [738], 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