Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2131427477', 'doi': 'https://doi.org/10.1186/1476-4598-9-224', 'title': 'A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ', 'display_name': 'A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ', 'publication_year': 2010, 'publication_date': '2010-08-25', 'ids': {'openalex': 'https://openalex.org/W2131427477', 'doi': 'https://doi.org/10.1186/1476-4598-9-224', 'mag': '2131427477', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20738847', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2936342'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1476-4598-9-224', 'pdf_url': 'https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-224', 'source': {'id': 'https://openalex.org/S132829192', 'display_name': 'Molecular Cancer', 'issn_l': '1476-4598', 'issn': ['1476-4598'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-224', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042450224', 'display_name': 'Zoi Diamantopoulou', 'orcid': 'https://orcid.org/0000-0002-2135-3986'}, 'institutions': [{'id': 'https://openalex.org/I174878644', 'display_name': 'University of Patras', 'ror': 'https://ror.org/017wvtq80', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I174878644']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Zoi Diamantopoulou', 'raw_affiliation_strings': ['Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.', 'institution_ids': ['https://openalex.org/I174878644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015513859', 'display_name': 'Oya Bermek', 'orcid': 'https://orcid.org/0000-0001-9320-0412'}, 'institutions': [{'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I197681013', 'display_name': 'Université Paris-Est Créteil', 'ror': 'https://ror.org/05ggc9x40', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I197681013']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210139303', 'display_name': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires', 'ror': 'https://ror.org/041dsyz88', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I197681013', 'https://openalex.org/I4210139303']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Oya Bermek', 'raw_affiliation_strings': ['Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.', 'institution_ids': ['https://openalex.org/I204730241', 'https://openalex.org/I197681013', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210139303']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006729179', 'display_name': 'Apostolos Polykratis', 'orcid': 'https://orcid.org/0000-0001-6720-3302'}, 'institutions': [{'id': 'https://openalex.org/I174878644', 'display_name': 'University of Patras', 'ror': 'https://ror.org/017wvtq80', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I174878644']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Apostolos Polykratis', 'raw_affiliation_strings': ['Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.', 'institution_ids': ['https://openalex.org/I174878644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002180641', 'display_name': 'Yamina Hamma‐Kourbali', 'orcid': 'https://orcid.org/0000-0002-2754-8928'}, 'institutions': [{'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I197681013', 'display_name': 'Université Paris-Est Créteil', 'ror': 'https://ror.org/05ggc9x40', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I197681013']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210139303', 'display_name': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires', 'ror': 'https://ror.org/041dsyz88', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I197681013', 'https://openalex.org/I4210139303']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Yamina Hamma-Kourbali', 'raw_affiliation_strings': ['Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.', 'institution_ids': ['https://openalex.org/I204730241', 'https://openalex.org/I197681013', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210139303']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068249801', 'display_name': 'Jean Delbé', 'orcid': 'https://orcid.org/0000-0001-6504-0159'}, 'institutions': [{'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I197681013', 'display_name': 'Université Paris-Est Créteil', 'ror': 'https://ror.org/05ggc9x40', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I197681013']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210139303', 'display_name': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires', 'ror': 'https://ror.org/041dsyz88', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I197681013', 'https://openalex.org/I4210139303']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean Delbé', 'raw_affiliation_strings': ['Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.', 'institution_ids': ['https://openalex.org/I204730241', 'https://openalex.org/I197681013', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210139303']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049770365', 'display_name': 'Maria Hatziapostolou', 'orcid': 'https://orcid.org/0000-0003-2493-7028'}, 'institutions': [{'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I197681013', 'display_name': 'Université Paris-Est Créteil', 'ror': 'https://ror.org/05ggc9x40', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I197681013']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210139303', 'display_name': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires', 'ror': 'https://ror.org/041dsyz88', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I197681013', 'https://openalex.org/I4210139303']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'José Courty', 'raw_affiliation_strings': ['Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires (CRRET), CNRS UMR 7149, Université Paris XII, Créteil Cedex, France.', 'institution_ids': ['https://openalex.org/I204730241', 'https://openalex.org/I197681013', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210139303']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5080763424', 'display_name': 'Panagiotis Katsoris', 'orcid': 'https://orcid.org/0009-0004-2057-9475'}, 'institutions': [{'id': 'https://openalex.org/I174878644', 'display_name': 'University of Patras', 'ror': 'https://ror.org/017wvtq80', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I174878644']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Panagiotis Katsoris', 'raw_affiliation_strings': ['Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Division of Genetics, Cell and Developmental Biology, Department of Biology, University of Patras, Greece.', 'institution_ids': ['https://openalex.org/I174878644']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3170, 'currency': 'GBP', 'value_usd': 3888, 'provenance': 'doaj'}, 'apc_paid': {'value': 3170, 'currency': 'GBP', 'value_usd': 3888, 'provenance': 'doaj'}, 'fwci': 0.732, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.615787, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '9', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11131', 'display_name': 'Role of Extracellular Matrix in Biological Signaling', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11131', 'display_name': 'Role of Extracellular Matrix in Biological Signaling', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10831', 'display_name': 'Integrin Signaling in Inflammation and Cancer', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10620', 'display_name': 'Role of Matrix Metalloproteinases in Cancer and Physiology', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pleiotrophin', 'display_name': 'Pleiotrophin', 'score': 0.9983462}, {'id': 'https://openalex.org/keywords/cell-adhesion', 'display_name': 'Cell Adhesion', 'score': 0.456185}], 'concepts': [{'id': 'https://openalex.org/C2779822564', 'wikidata': 'https://www.wikidata.org/wiki/Q14916160', 'display_name': 'Pleiotrophin', 'level': 4, 'score': 0.9983462}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6532254}, {'id': 'https://openalex.org/C128240485', 'wikidata': 'https://www.wikidata.org/wiki/Q786998', 'display_name': 'Autocrine signalling', 'level': 3, 'score': 0.63250387}, {'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.5930766}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.53077686}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.50498134}, {'id': 'https://openalex.org/C7876069', 'wikidata': 'https://www.wikidata.org/wiki/Q14873666', 'display_name': 'Paracrine signalling', 'level': 3, 'score': 0.49620014}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.45044106}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.43053263}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2192361}], 'mesh': [{'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D010446', 'descriptor_name': 'Peptide Fragments', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D054633', 'descriptor_name': 'Receptor-Like Protein Tyrosine Phosphatases, Class 5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010446', 'descriptor_name': 'Peptide Fragments', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054633', 'descriptor_name': 'Receptor-Like Protein Tyrosine Phosphatases, Class 5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1476-4598-9-224', 'pdf_url': 'https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-224', 'source': {'id': 'https://openalex.org/S132829192', 'display_name': 'Molecular Cancer', 'issn_l': '1476-4598', 'issn': ['1476-4598'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/6df89cb82a27489fbe689e2e8d191403', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936342', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20738847', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1476-4598-9-224', 'pdf_url': 'https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-224', 'source': {'id': 'https://openalex.org/S132829192', 'display_name': 'Molecular Cancer', 'issn_l': '1476-4598', 'issn': ['1476-4598'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1233202794', 'https://openalex.org/W1520098011', 'https://openalex.org/W1565134347', 'https://openalex.org/W1581923812', 'https://openalex.org/W1582232587', 'https://openalex.org/W1968365109', 'https://openalex.org/W1969785535', 'https://openalex.org/W1969832217', 'https://openalex.org/W1975270312', 'https://openalex.org/W1979320351', 'https://openalex.org/W1985760282', 'https://openalex.org/W1992774566', 'https://openalex.org/W2006651878', 'https://openalex.org/W2021192518', 'https://openalex.org/W2022043843', 'https://openalex.org/W2032116260', 'https://openalex.org/W2043349045', 'https://openalex.org/W2044522243', 'https://openalex.org/W2044593069', 'https://openalex.org/W2046723647', 'https://openalex.org/W2051923628', 'https://openalex.org/W2060650047', 'https://openalex.org/W2061198459', 'https://openalex.org/W2067955405', 'https://openalex.org/W2068282262', 'https://openalex.org/W2073694641', 'https://openalex.org/W2076457965', 'https://openalex.org/W2077124345', 'https://openalex.org/W2080605009', 'https://openalex.org/W2086234005', 'https://openalex.org/W2088231881', 'https://openalex.org/W2088320968', 'https://openalex.org/W2095533841', 'https://openalex.org/W2099784353', 'https://openalex.org/W2108412857', 'https://openalex.org/W2111062014', 'https://openalex.org/W2119930698', 'https://openalex.org/W2126370825', 'https://openalex.org/W2162923066'], 'related_works': ['https://openalex.org/W4247493430', 'https://openalex.org/W3004047898', 'https://openalex.org/W2487558127', 'https://openalex.org/W2367035282', 'https://openalex.org/W2099619041', 'https://openalex.org/W2091727603', 'https://openalex.org/W2085869617', 'https://openalex.org/W2015867957', 'https://openalex.org/W1996832816', 'https://openalex.org/W1963652002'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Pleiotrophin,': [2], 'also': [3, 154], 'known': [4], 'as': [5, 116, 160], 'HARP': [6], '(Heparin': [7], 'Affin': [8], 'Regulatory': [9], 'Peptide)': [10], 'is': [11, 38], 'a': [12, 69, 192, 216], 'growth': [13, 80], 'factor': [14], 'expressed': [15], 'in': [16, 24, 40, 89, 113, 195], 'various': [17], 'tissues': [18], 'and': [19, 35, 37, 45, 94, 98, 104, 140, 202, 220], 'cell': [20], 'lines.': [21], 'Pleiotrophin': [22], 'participates': [23], 'multiple': [25], 'biological': [26, 52, 65, 183], 'actions': [27, 66], 'including': [28], 'the': [29, 64, 74, 119, 126, 133, 171, 189], 'induction': [30, 190], 'of': [31, 59, 67, 78, 96, 125, 136, 165, 191, 225], 'cellular': [32], 'proliferation,': [33, 93], 'migration': [34, 95], 'angiogenesis,': [36], 'involved': [39], 'carcinogenesis.': [41], 'Recently,': [42], 'we': [43, 62], 'identified': [44], 'characterized': [46], 'several': [47], 'pleiotrophin': [48, 103, 158, 166, 206], 'proteolytic': [49], 'fragments': [50], 'with': [51, 151, 156, 170, 200, 204], 'activities': [53, 184], 'similar': [54], 'or': [55, 167], 'opposite': [56], 'to': [57, 73, 188], 'that': [58, 86, 130, 180, 185, 212], 'pleiotrophin.': [60], 'Here,': [61], 'investigated': [63], 'P(122-131),': [68], 'synthetic': [70], 'peptide': [71], 'corresponding': [72], 'carboxy': [75], 'terminal': [76], 'region': [77], 'this': [79, 226], 'factor.': [81], 'Results': [82], 'Our': [83], 'results': [84, 178, 210], 'show': [85], 'P(122-131)': [87, 110, 131, 147, 181, 213], 'inhibits': [88, 111, 182], 'vitro': [90], 'adhesion,': [91], 'anchorage-independent': [92], 'DU145': [97], 'LNCaP': [99], 'cells,': [100, 197], 'which': [101], 'express': [102], 'its': [105], 'receptor': [106], 'RPTPβ/ζ.': [107], 'In': [108, 175], 'addition,': [109], 'angiogenesis': [112], 'vivo': [114], ',': [115], 'determined': [117], 'by': [118, 162, 198], 'chicken': [120], 'embryo': [121], 'CAM': [122], 'assay.': [123], 'Investigation': [124], 'transduction': [127], 'mechanisms': [128], 'revealed': [129], 'reduces': [132], 'phosphorylation': [134], 'levels': [135], 'Src,': [137], 'Pten,': [138], 'Fak,': [139], 'Erk': [141], '1': [142], '/': [143], '2': [144], '.': [145], 'Finally,': [146], 'not': [148], 'only': [149], 'interacts': [150], 'RPTPβ/ζ,': [152], 'but': [153], 'interferes': [155], 'other': [157, 205], 'receptors,': [159], 'demonstrated': [161], 'selective': [163], 'knockdown': [164], 'RPTPβ/ζ': [168, 201], 'expression': [169], 'RNAi': [172], 'technology.': [173], 'Conclusions': [174], 'conclusion,': [176], 'our': [177], 'demonstrate': [179], 'are': [186], 'related': [187], 'transformed': [193], 'phenotype': [194], 'PCa': [196], 'interacing': [199], 'interfering': [203], 'receptors.': [207], 'Cumulatively,': [208], 'these': [209], 'indicate': [211], 'may': [214], 'be': [215], 'potential': [217], 'anticancer': [218], 'agent,': [219], 'they': [221], 'warrant': [222], 'further': [223], 'study': [224], 'peptide.': [227]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2131427477', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-09-27T01:08:46.955378', 'created_date': '2016-06-24'}