Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2106007139', 'doi': 'https://doi.org/10.1128/jvi.00371-07', 'title': 'Nuclear Import and Export of Venezuelan Equine Encephalitis Virus Nonstructural Protein 2', 'display_name': 'Nuclear Import and Export of Venezuelan Equine Encephalitis Virus Nonstructural Protein 2', 'publication_year': 2007, 'publication_date': '2007-07-26', 'ids': {'openalex': 'https://openalex.org/W2106007139', 'doi': 'https://doi.org/10.1128/jvi.00371-07', 'mag': '2106007139', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17652399', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2045464'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/jvi.00371-07', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2045464?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062608685', 'display_name': 'Stephanie A. Montgomery', 'orcid': 'https://orcid.org/0000-0001-8012-5302'}, 'institutions': [{'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephanie A. Montgomery', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, Carolina Vaccine Institute, University of North Carolina-Chapel Hill, CB 7292, Burnett-Womack Room 9005, Chapel Hill, NC 27599, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Carolina Vaccine Institute, University of North Carolina-Chapel Hill, CB 7292, Burnett-Womack Room 9005, Chapel Hill, NC 27599, USA.', 'institution_ids': ['https://openalex.org/I114027177']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103406182', 'display_name': 'Robert E. Johnston', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert E. Johnston', 'raw_affiliation_strings': ['Department of Microbiology and Immunology and Carolina Vaccine Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology and Carolina Vaccine Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599', 'institution_ids': ['https://openalex.org/I114027177']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.005, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.880556, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '81', 'issue': '19', 'first_page': '10268', 'last_page': '10279'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12047', 'display_name': 'Viral Infections and Vectors', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11581', 'display_name': 'Viral Infections and Outbreaks Research', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/karyopherin', 'display_name': 'Karyopherin', 'score': 0.96848214}, {'id': 'https://openalex.org/keywords/nuclear-export-signal', 'display_name': 'Nuclear export signal', 'score': 0.88674253}, {'id': 'https://openalex.org/keywords/importin', 'display_name': 'Importin', 'score': 0.6027363}, {'id': 'https://openalex.org/keywords/nls', 'display_name': 'NLS', 'score': 0.46599948}], 'concepts': [{'id': 'https://openalex.org/C2777336224', 'wikidata': 'https://www.wikidata.org/wiki/Q3193641', 'display_name': 'Karyopherin', 'level': 5, 'score': 0.96848214}, {'id': 'https://openalex.org/C59157529', 'wikidata': 'https://www.wikidata.org/wiki/Q994741', 'display_name': 'Nuclear transport', 'level': 4, 'score': 0.8989216}, {'id': 'https://openalex.org/C54757728', 'wikidata': 'https://www.wikidata.org/wiki/Q3511067', 'display_name': 'Nuclear export signal', 'level': 4, 'score': 0.88674253}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.85049856}, {'id': 'https://openalex.org/C49805395', 'wikidata': 'https://www.wikidata.org/wiki/Q910966', 'display_name': 'Nuclear localization sequence', 'level': 3, 'score': 0.8368026}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.63005006}, {'id': 'https://openalex.org/C133882971', 'wikidata': 'https://www.wikidata.org/wiki/Q24205524', 'display_name': 'Importin', 'level': 5, 'score': 0.6027363}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5733336}, {'id': 'https://openalex.org/C29512474', 'wikidata': 'https://www.wikidata.org/wiki/Q16860021', 'display_name': 'Nuclear protein', 'level': 4, 'score': 0.55828136}, {'id': 'https://openalex.org/C2780114586', 'wikidata': 'https://www.wikidata.org/wiki/Q40260', 'display_name': 'Cell nucleus', 'level': 3, 'score': 0.5104703}, {'id': 'https://openalex.org/C186435350', 'wikidata': 'https://www.wikidata.org/wiki/Q1050365', 'display_name': 'NLS', 'level': 4, 'score': 0.46599948}, {'id': 'https://openalex.org/C2780723820', 'wikidata': 'https://www.wikidata.org/wiki/Q1934178', 'display_name': 'Nucleus', 'level': 2, 'score': 0.44491237}, {'id': 'https://openalex.org/C2777474056', 'wikidata': 'https://www.wikidata.org/wiki/Q1111605', 'display_name': 'Alphavirus', 'level': 3, 'score': 0.43929464}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.4275739}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.28357345}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.22219837}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.09929782}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.06361738}], 'mesh': [{'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004666', 'descriptor_name': 'Encephalitis Virus, Venezuelan Equine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D017361', 'descriptor_name': 'Viral Nonstructural Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D021581', 'descriptor_name': 'Active Transport, Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004666', 'descriptor_name': 'Encephalitis Virus, Venezuelan Equine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017361', 'descriptor_name': 'Viral Nonstructural Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D017361', 'descriptor_name': 'Viral Nonstructural Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017361', 'descriptor_name': 'Viral Nonstructural Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D028901', 'descriptor_name': 'alpha Karyopherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D028901', 'descriptor_name': 'alpha Karyopherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/jvi.00371-07', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2045464', 'pdf_url': 'https://europepmc.org/articles/pmc2045464?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.17615/vxgr-mf84', 'pdf_url': 'https://cdr.lib.unc.edu/downloads/d791sq076', 'source': {'id': 'https://openalex.org/S4306401075', 'display_name': 'Carolina Digital Repository (University of North Carolina at Chapel Hill)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I114027177', 'host_organization_name': 'University of North Carolina at Chapel Hill', 'host_organization_lineage': ['https://openalex.org/I114027177'], 'host_organization_lineage_names': ['University of North Carolina at Chapel Hill'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045464', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17652399', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2045464', 'pdf_url': 'https://europepmc.org/articles/pmc2045464?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.59, 'id': 'https://metadata.un.org/sdg/12', 'display_name': 'Responsible consumption and production'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 69, 'referenced_works': ['https://openalex.org/W1515948420', 'https://openalex.org/W1524816607', 'https://openalex.org/W1543019819', 'https://openalex.org/W1554634228', 'https://openalex.org/W1560019489', 'https://openalex.org/W1565506774', 'https://openalex.org/W1568604491', 'https://openalex.org/W1573694969', 'https://openalex.org/W1579957748', 'https://openalex.org/W1627945794', 'https://openalex.org/W1638093133', 'https://openalex.org/W1667933161', 'https://openalex.org/W1716707690', 'https://openalex.org/W178738058', 'https://openalex.org/W1855484651', 'https://openalex.org/W1921346031', 'https://openalex.org/W1954022543', 'https://openalex.org/W1966055810', 'https://openalex.org/W1968072008', 'https://openalex.org/W1980932758', 'https://openalex.org/W1986406001', 'https://openalex.org/W1989700964', 'https://openalex.org/W1992893207', 'https://openalex.org/W1994329750', 'https://openalex.org/W1994822654', 'https://openalex.org/W1995799060', 'https://openalex.org/W1996313023', 'https://openalex.org/W1997992792', 'https://openalex.org/W2000081661', 'https://openalex.org/W2009975411', 'https://openalex.org/W2026641742', 'https://openalex.org/W2028339539', 'https://openalex.org/W2034377840', 'https://openalex.org/W2037448519', 'https://openalex.org/W2042249918', 'https://openalex.org/W2044490480', 'https://openalex.org/W2050723214', 'https://openalex.org/W2055047899', 'https://openalex.org/W2056367972', 'https://openalex.org/W2064867196', 'https://openalex.org/W2073700378', 'https://openalex.org/W2078913553', 'https://openalex.org/W2083563185', 'https://openalex.org/W2086910521', 'https://openalex.org/W2096507556', 'https://openalex.org/W2098683222', 'https://openalex.org/W2102799805', 'https://openalex.org/W2108718318', 'https://openalex.org/W2110310164', 'https://openalex.org/W2111768999', 'https://openalex.org/W2116621112', 'https://openalex.org/W2117856297', 'https://openalex.org/W2118814257', 'https://openalex.org/W2121306694', 'https://openalex.org/W2123865393', 'https://openalex.org/W2130804993', 'https://openalex.org/W2134708393', 'https://openalex.org/W2135336573', 'https://openalex.org/W2136920638', 'https://openalex.org/W2139872963', 'https://openalex.org/W2147093282', 'https://openalex.org/W2151991090', 'https://openalex.org/W2165534020', 'https://openalex.org/W2168130018', 'https://openalex.org/W2222638288', 'https://openalex.org/W2404924110', 'https://openalex.org/W288658508', 'https://openalex.org/W4210291135', 'https://openalex.org/W4233808990'], 'related_works': ['https://openalex.org/W3212634673', 'https://openalex.org/W3122888278', 'https://openalex.org/W2674831059', 'https://openalex.org/W2257582870', 'https://openalex.org/W2165964303', 'https://openalex.org/W2109495138', 'https://openalex.org/W2067099248', 'https://openalex.org/W2005795074', 'https://openalex.org/W1989700964', 'https://openalex.org/W1625027797'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Many': [1], 'RNA': [2], 'viruses,': [3], 'which': [4, 175], 'replicate': [5], 'predominantly': [6], 'in': [7, 33, 62, 188, 215], 'the': [8, 23, 27, 54, 57, 63, 73, 92, 104, 116, 119, 124, 132, 144, 162, 202, 210, 213, 226, 232, 248, 251], 'cytoplasm,': [9], 'have': [10], 'nuclear': [11, 106, 133, 145, 169, 189, 195, 204, 233], 'components': [12], 'that': [13, 88, 127, 157, 194, 236], 'contribute': [14], 'to': [15, 52, 91, 121, 123, 131, 161], 'their': [16], 'life': [17], 'cycle': [18], 'or': [19, 154, 212], 'pathogenesis.': [20], 'We': [21], 'investigated': [22], 'intracellular': [24], 'localization': [25, 107, 134], 'of': [26, 59, 65, 75, 78, 86, 94, 103, 118, 135, 181, 191, 197, 208, 229, 240], 'multifunctional': [28], 'nonstructural': [29], 'protein': [30, 82, 120, 147], '2': [31], '(nsP2)': [32], 'mammalian': [34, 60, 95], 'cells': [35, 61, 96], 'infected': [36], 'with': [37, 143, 151], 'Venezuelan': [38], 'equine': [39], 'encephalitis': [40], 'virus': [41], '(VEE),': [42], 'an': [43], 'important,': [44], 'naturally': [45], 'emerging': [46], 'zoonotic': [47], 'alphavirus.': [48], 'VEE': [49, 136, 139, 182], 'nsP2': [50, 87, 140, 160, 198, 216, 230, 241], 'localizes': [51, 90], 'both': [53], 'cytoplasm': [55, 249], 'and': [56, 67, 179, 250], 'nucleus': [58, 93, 163], 'context': [64], 'infection': [66, 243], 'also': [68], 'when': [69], 'expressed': [70], 'alone.': [71], 'Through': [72], 'analysis': [74], 'a': [76, 84, 167, 237], 'series': [77], 'enhanced': [79], 'green': [80], 'fluorescent': [81], 'fusions,': [83], 'segment': [85], 'completely': [89], 'was': [97, 173], 'identified.': [98], 'Within': [99], 'this': [100, 128], 'region,': [101], 'mutation': [102], 'putative': [105], 'signal': [108, 171], '(NLS)': [109], 'PGKMV': [110], 'diminished,': [111], 'but': [112, 149], 'did': [113], 'not': [114, 150], 'obliterate,': [115], 'ability': [117], 'localize': [122], 'nucleus,': [125], 'suggesting': [126, 156, 235], 'sequence': [129], 'contributes': [130], 'nsP2.': [137, 183], 'Furthermore,': [138], 'specifically': [141], 'interacted': [142], 'import': [146], 'karyopherin-α1': [148, 158], 'karyopherin-α2,': [152], '-3,': [153], '-4,': [155], 'transports': [159], 'during': [164, 242], 'infection.': [165], 'Additionally,': [166], 'novel': [168], 'export': [170, 196, 205], '(NES)': [172], 'identified,': [174], 'included': [176], 'residues': [177], 'L526': [178], 'L528': [180], 'Leptomycin': [184], 'B': [185], 'treatment': [186], 'resulted': [187], 'accumulation': [190], 'nsP2,': [192], 'demonstrating': [193], 'is': [199], 'mediated': [200], 'via': [201], 'CRM1': [203], 'pathway.': [206], 'Disruption': [207], 'either': [209], 'NLS': [211], 'NES': [214], 'compromised': [217], 'essential': [218], 'viral': [219], 'functions.': [220], 'Taken': [221], 'together,': [222], 'these': [223], 'results': [224], 'establish': [225], 'bidirectional': [227], 'transport': [228], 'across': [231], 'membrane,': [234], 'critical': [238], 'function': [239], 'involves': [244], 'its': [245], 'shuttling': [246], 'between': [247], 'nucleus.': [252]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2106007139', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}], 'updated_date': '2024-12-20T12:31:23.855205', 'created_date': '2016-06-24'}