Title: 2-D And 3-D Reconstructions Of The Olfactory System Of The Rat
Abstract: The olfactory system of the rat is a useful model for the study of mammalian sensory systems. However, the anatomy of the nasal epithelium, where the cells responsible for detecting odors are located, is extremely complex. Therefore, we have focused our attention on the development of two- and three-dimensional automated imaging methods. The presentation of pure odorants to the experimental animal together with the injection of [<sup>14</sup>M-deoxyglucose has been combined with autoradiography of frozen sectioned material. Several approaches have been used to obtain optimal alignments of the digitized images of the sections so as to be able to generate appropriate 2-D and 3-D reconstructions. Such reconstructions allow visualization of the ethmo-turbinal bones (turbinates) and the associated soft tissue and appear to be useful in analyzing and highlighting differential metabolic activity.
Publication Year: 1989
Publication Date: 1989-04-14
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 2
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