Publication Information

{'id': 'https://openalex.org/W2068520033', 'doi': 'https://doi.org/10.3390/molecules18033168', 'title': 'Dynamic Motion and Rearranged Molecular Shape of Heme in Myoglobin: Structural and Functional Consequences', 'display_name': 'Dynamic Motion and Rearranged Molecular Shape of Heme in Myoglobin: Structural and Functional Consequences', 'publication_year': 2013, 'publication_date': '2013-03-11', 'ids': {'openalex': 'https://openalex.org/W2068520033', 'doi': 'https://doi.org/10.3390/molecules18033168', 'mag': '2068520033', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23478515', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6269712'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules18033168', 'pdf_url': 'https://www.mdpi.com/1420-3049/18/3/3168/pdf?version=1403114612', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1420-3049/18/3/3168/pdf?version=1403114612', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5024525915', 'display_name': 'Saburo Neya', 'orcid': 'https://orcid.org/0000-0002-2203-5760'}, 'institutions': [{'id': 'https://openalex.org/I159385669', 'display_name': 'Chiba University', 'ror': 'https://ror.org/01hjzeq58', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I159385669']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Saburo Neya', 'raw_affiliation_strings': ['Department of Physical Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chuoh-Inohana, Chiba City, Chiba 260-8675, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Physical Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chuoh-Inohana, Chiba City, Chiba 260-8675, Japan.', 'institution_ids': ['https://openalex.org/I159385669']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5024525915'], 'corresponding_institution_ids': ['https://openalex.org/I159385669'], 'apc_list': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 0.122, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.20386, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '18', 'issue': '3', 'first_page': '3168', 'last_page': '3182'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12068', 'display_name': 'Neonatal Health and Biochemistry', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12381', 'display_name': 'Electron Spin Resonance Studies', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1304', 'display_name': 'Biophysics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hemeprotein', 'display_name': 'Hemeprotein', 'score': 0.6350211}, {'id': 'https://openalex.org/keywords/protein-dynamics', 'display_name': 'Protein Dynamics', 'score': 0.42401716}], 'concepts': [{'id': 'https://openalex.org/C2776217839', 'wikidata': 'https://www.wikidata.org/wiki/Q189621', 'display_name': 'Heme', 'level': 3, 'score': 0.94103575}, {'id': 'https://openalex.org/C2778063876', 'wikidata': 'https://www.wikidata.org/wiki/Q192642', 'display_name': 'Myoglobin', 'level': 2, 'score': 0.9351095}, {'id': 'https://openalex.org/C125996951', 'wikidata': 'https://www.wikidata.org/wiki/Q412234', 'display_name': 'Globin', 'level': 3, 'score': 0.8739524}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.69517636}, {'id': 'https://openalex.org/C20705724', 'wikidata': 'https://www.wikidata.org/wiki/Q902628', 'display_name': 'Hemeprotein', 'level': 4, 'score': 0.6350211}, {'id': 'https://openalex.org/C2778460671', 'wikidata': 'https://www.wikidata.org/wiki/Q485277', 'display_name': 'Histidine', 'level': 3, 'score': 0.52148783}, {'id': 'https://openalex.org/C2779480358', 'wikidata': 'https://www.wikidata.org/wiki/Q422926', 'display_name': 'Porphyrin', 'level': 2, 'score': 0.5030908}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.464082}, {'id': 'https://openalex.org/C2775981520', 'wikidata': 'https://www.wikidata.org/wiki/Q17156992', 'display_name': 'Protein dynamics', 'level': 3, 'score': 0.42401716}, {'id': 'https://openalex.org/C47701112', 'wikidata': 'https://www.wikidata.org/wiki/Q735188', 'display_name': 'Protein structure', 'level': 2, 'score': 0.418608}, {'id': 'https://openalex.org/C8010536', 'wikidata': 'https://www.wikidata.org/wiki/Q160398', 'display_name': 'Crystallography', 'level': 1, 'score': 0.38009202}, {'id': 'https://openalex.org/C2778917026', 'wikidata': 'https://www.wikidata.org/wiki/Q43041', 'display_name': 'Hemoglobin', 'level': 2, 'score': 0.36919403}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.3673113}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.31890512}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.13457409}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.10367036}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.07752192}], 'mesh': [{'descriptor_ui': 'D006418', 'descriptor_name': 'Heme', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D009038', 'descriptor_name': 'Motion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009211', 'descriptor_name': 'Myoglobin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D002248', 'descriptor_name': 'Carbon Monoxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002248', 'descriptor_name': 'Carbon Monoxide', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D018360', 'descriptor_name': 'Crystallography, X-Ray', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006418', 'descriptor_name': 'Heme', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006639', 'descriptor_name': 'Histidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006639', 'descriptor_name': 'Histidine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009211', 'descriptor_name': 'Myoglobin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019906', 'descriptor_name': 'Nuclear Magnetic Resonance, Biomolecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012399', 'descriptor_name': 'Rotation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules18033168', 'pdf_url': 'https://www.mdpi.com/1420-3049/18/3/3168/pdf?version=1403114612', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/49a257b285994c2c84fba503625e40b6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6269712', 'pdf_url': 'https://europepmc.org/articles/pmc6269712?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269712', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.368.1103', 'pdf_url': 'http://www.mdpi.com/1420-3049/18/3/3168/pdf?y=1', 'source': {'id': 'https://openalex.org/S4306400349', 'display_name': 'CiteSeer X (The Pennsylvania State University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I130769515', 'host_organization_name': 'Pennsylvania State University', 'host_organization_lineage': ['https://openalex.org/I130769515'], 'host_organization_lineage_names': ['Pennsylvania State University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23478515', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/molecules18033168', 'pdf_url': 'https://www.mdpi.com/1420-3049/18/3/3168/pdf?version=1403114612', 'source': {'id': 'https://openalex.org/S108911230', 'display_name': 'Molecules', 'issn_l': '1420-3049', 'issn': ['1420-3049', '1433-1373'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W1481033123', 'https://openalex.org/W1488821433', 'https://openalex.org/W1499060024', 'https://openalex.org/W1512775211', 'https://openalex.org/W1517663550', 'https://openalex.org/W1518736393', 'https://openalex.org/W1522117607', 'https://openalex.org/W1532186861', 'https://openalex.org/W1935171583', 'https://openalex.org/W1963566077', 'https://openalex.org/W1969093733', 'https://openalex.org/W1972190772', 'https://openalex.org/W1977492851', 'https://openalex.org/W1977637187', 'https://openalex.org/W1978044305', 'https://openalex.org/W1985854865', 'https://openalex.org/W1990830258', 'https://openalex.org/W1992336464', 'https://openalex.org/W1996610300', 'https://openalex.org/W2000563955', 'https://openalex.org/W2006483567', 'https://openalex.org/W2006999117', 'https://openalex.org/W2009541344', 'https://openalex.org/W2017490569', 'https://openalex.org/W2024575202', 'https://openalex.org/W2028514569', 'https://openalex.org/W2030449413', 'https://openalex.org/W2044791333', 'https://openalex.org/W2052241609', 'https://openalex.org/W2058788084', 'https://openalex.org/W2059003981', 'https://openalex.org/W2068863008', 'https://openalex.org/W2084566821', 'https://openalex.org/W2089224023', 'https://openalex.org/W2095998582', 'https://openalex.org/W2096700300', 'https://openalex.org/W2139082246', 'https://openalex.org/W2161429942', 'https://openalex.org/W2164964031', 'https://openalex.org/W4250441726', 'https://openalex.org/W70007395', 'https://openalex.org/W957695923'], 'related_works': ['https://openalex.org/W2952643234', 'https://openalex.org/W2465600400', 'https://openalex.org/W2066422807', 'https://openalex.org/W2020647158', 'https://openalex.org/W2013942846', 'https://openalex.org/W1996610300', 'https://openalex.org/W1993983571', 'https://openalex.org/W1992645297', 'https://openalex.org/W1989270872', 'https://openalex.org/W1522117607'], 'abstract_inverted_index': {'Myoglobin,': [0], 'a': [1, 38, 59], 'simple': [2], 'oxygen': [3, 115], 'binding': [4, 103], 'protein,': [5], 'was': [6, 26, 62, 82], 'reconstituted': [7], 'with': [8], 'various': [9], 'types': [10], 'of': [11, 46, 58, 76, 87, 93, 101, 123, 138, 160], 'synthetic': [12], 'hemes': [13], 'to': [14, 28, 85, 149], 'manipulate': [15], 'the': [16, 20, 32, 44, 54, 73, 79, 94, 106, 114, 118, 121, 127, 135, 146, 151, 157, 166], 'heme-globin': [17, 96, 108, 168], 'interactions.': [18, 97], 'From': [19], 'paramagnetic': [21], 'NMR': [22, 50], 'analysis,': [23], 'small': [24, 60], 'heme': [25, 61, 81], 'found': [27], 'rotate': [29], 'rapidly': [30], 'about': [31], 'iron-histidine': [33], 'bond': [34], 'upon.': [35], 'This': [36], 'is': [37], 'novel': [39], 'and': [40, 126], 'typical': [41], 'example': [42], 'for': [43], 'fluctuation': [45], 'protein.': [47], 'The': [48, 68, 98], 'dynamic': [49], 'analysis': [51], 'indicated': [52], 'that': [53, 72, 86, 105, 145], '360°': [55], 'rotational': [56], 'rate': [57], '1,400': [63], 's−1': [64], 'at': [65], 'room': [66], 'temperature.': [67], 'X-ray': [69], 'analyses': [70, 100], 'revealed': [71], 'tertiary': [74], 'structure': [75], 'globin': [77], 'containing': [78], 'smallest': [80], 'closely': [83], 'similar': [84], 'native': [88], 'protein': [89], 'despite': [90], 'extensive': [91], 'destruction': [92], 'specific': [95], 'functional': [99, 136], 'O2': [102], 'showed': [104], 'loose': [107], 'contacts': [109], 'do': [110], 'not': [111], 'significantly': [112, 133], 'affect': [113, 134], 'binding.': [116], 'On': [117], 'other': [119], 'hand,': [120], 'rearrangement': [122], 'tetrapyrrole': [124], 'array': [125], 'non-planar': [128], 'deformation': [129], 'in': [130, 165], 'porphyrin': [131], 'ring': [132], 'properties': [137], 'myoglobin.': [139], 'These': [140], 'results,': [141], 'taken': [142], 'together,': [143], 'indicate': [144], 'essential': [147], 'factors': [148], 'regulate': [150], 'myoglobin': [152], 'function': [153], 'are': [154], 'hidden': [155], 'under': [156], 'molecular': [158], 'shape': [159], 'prosthetic': [161], 'group': [162], 'rather': [163], 'than': [164], 'nonbonded': [167], 'contacts.': [169]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2068520033', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-12-08T15:30:34.275598', 'created_date': '2016-06-24'}