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'cloned': [57, 180, 522, 652, 1410, 1540], 'HDAC1.': [59, 182], 'Comparison': [60, 183], 'HDAC2': [67, 190, 740, 749, 841, 1628, 1637, 1729], 'also': [68, 191, 613, 948, 1501, 1836], 'yielded': [69, 192], 'similar': [70, 193], 'results,': [71, 194], '51%': [73, 196], 'identity': [74, 80, 197, 203], '52%': [79, 202], 'sequence.': [83, 206], 'expressed': [85, 117, 208, 240], 'functionally': [89, 212], 'active': [90, 213, 265, 1152], 'because': [91, 214], 'it': [92, 215, 674, 1058, 1116, 1562, 1947, 2005], 'possesses': [93, 216], 'activity,': [96, 219], 'represses': [97, 220, 953, 1107, 1841, 1996], 'transcription': [98, 106, 221, 229, 367, 704, 737, 1108, 1111, 1254, 1592, 1625, 1997, 2000], 'when': [99, 222], 'tethered': [100, 223], 'to': [101, 110, 224, 233, 287, 297, 599, 658, 689, 741, 1174, 1184, 1487, 1546, 1577, 1629], 'promoter,': [103, 226], 'binds': [105, 228, 1110, 1999], 'factor': [107, 230, 705, 951, 1112, 1593, 1839, 2001], 'YY1.': [108, 231], 'Similar': [109, 232], 'HDAC1': [111, 234, 668, 747, 839, 946, 1103, 1556, 1635, 1727, 1834, 1992], 'HDAC2,': [113, 236, 685, 1105, 1573, 1994], 'ubiquitously': [116, 239], 'many': [119, 242], 'different': [120, 243, 378, 1265], 'cell': [121, 244], 'types.': [122, 245], 'organization': [247, 1134], 'chromatin': [249, 268, 1136, 1155], 'structure': [250, 1137], 'fundamental': [253, 1140], 'significant': [255, 1142], 'component': [256, 1143], 'transcriptional': [258, 761, 995, 1083, 1145, 1649, 1884, 1972], 'regulation': [259, 1146], 'all': [261, 1148], 'eukaryotic': [262, 1149], 'cells.': [263, 1150], 'Transcriptionally': [264, 1151], 'or': [266, 1076, 1153, 1965], 'repressed': [267, 1154], 'determined,': [270, 1157], 'at': [271, 1158], 'least': [272, 1159], 'part,': [274, 1161], 'by': [275, 738, 955, 1162, 1626, 1843], 'modification': [277, 1164], 'histones.': [279, 1166], 'For': [280, 1167], 'example,': [281, 1168], 'hyperacetylation': [282, 1169], 'histones': [284, 295, 1171, 1182], 'generally': [285, 1172], 'leads': [286, 1173], 'increase': [289, 1176], 'transcription,': [291, 1178], 'whereas': [292, 1179], 'hypoacetylation': [293, 1180], 'appears': [296, 1183], 'opposite': [300, 1187], 'effect': [301, 1188], '(reviewed': [302, 1189], 'Refs.': [304, 1191], '1Brownell': [305, 1192], 'J.E.': [306, 381, 415, 486, 1193, 1268, 1302, 1373], 'Allis': [307, 392, 430, 497, 1194, 1279, 1317, 1384], 'C.D.': [308, 393, 431, 498, 788, 863, 1195, 1280, 1318, 1385, 1676, 1751], 'Curr.': [309, 336, 1196, 1223], 'Opin.': [310, 1197], 'Genet.': [311, 1198], 'Dev.': [312, 1199], '1996;': [313, 324, 354, 395, 433, 451, 470, 500, 530, 555, 582, 642, 726, 1040, 1200, 1211, 1241, 1282, 1320, 1338, 1357, 1387, 1418, 1443, 1470, 1530, 1614, 1929], '6:': [314, 1201], '176-184Crossref': [315, 1202], 'PubMed': [316, 327, 346, 357, 403, 441, 454, 478, 503, 533, 558, 585, 645, 729, 782, 808, 832, 888, 911, 941, 980, 1007, 1043, 1203, 1214, 1233, 1244, 1290, 1328, 1341, 1365, 1390, 1421, 1446, 1473, 1533, 1617, 1670, 1696, 1720, 1776, 1799, 1829, 1868, 1896, 1932], 'Scopus': [317, 328, 358, 404, 442, 455, 479, 504, 534, 559, 586, 646, 730, 783, 809, 833, 889, 912, 942, 981, 1008, 1044, 1204, 1215, 1245, 1291, 1329, 1342, 1366, 1391, 1422, 1447, 1474, 1534, 1618, 1671, 1697, 1721, 1777, 1800, 1830, 1869, 1897, 1933], '(463)': [318, 1205], 'Google': [319, 330, 347, 360, 406, 444, 457, 481, 506, 536, 561, 588, 648, 732, 785, 811, 835, 891, 914, 944, 983, 1010, 1046, 1206, 1217, 1234, 1247, 1293, 1331, 1344, 1368, 1393, 1424, 1449, 1476, 1536, 1620, 1673, 1699, 1723, 1779, 1802, 1832, 1871, 1899, 1935], 'Scholar,': [320, 331, 348, 407, 445, 458, 482, 537, 562, 786, 812, 892, 915, 1207, 1218, 1235, 1294, 1332, 1345, 1369, 1425, 1450, 1674, 1700, 1780, 1803], '2Wolffe': [321, 1208], 'A.P.': [322, 335, 1209, 1222], 'Science.': [323, 529, 641, 1210, 1417, 1529], '272:': [325, 531, 643, 1212, 1419, 1531], '371-372Crossref': [326, 1213], '(271)': [329, 1216], '3Wade': [332, 1219], 'P.A.': [333, 1220], 'Wolffe': [334, 1221], 'Biol.': [337, 1003, 1224, 1892], '1997;': [338, 774, 800, 824, 885, 908, 933, 977, 1225, 1662, 1688, 1712, 1773, 1796, 1821, 1865], '7:': [339, 1226], 'R82-R84Abstract': [340, 1227], 'Full': [341, 343, 398, 400, 436, 438, 473, 475, 777, 779, 803, 805, 827, 829, 936, 938, 1228, 1230, 1285, 1287, 1323, 1325, 1360, 1362, 1665, 1667, 1691, 1693, 1715, 1717, 1824, 1826], 'Text': [342, 344, 399, 401, 437, 439, 474, 476, 778, 780, 804, 806, 828, 830, 937, 939, 1229, 1231, 1286, 1288, 1324, 1326, 1361, 1363, 1666, 1668, 1692, 1694, 1716, 1718, 1825, 1827], 'PDF': [345, 402, 440, 477, 781, 807, 831, 940, 1232, 1289, 1327, 1364, 1669, 1695, 1719, 1828], '4Davie': [349, 1236], 'J.R.': [350, 794, 873, 1237, 1682, 1761], 'J.': [351, 383, 421, 524, 636, 865, 900, 1238, 1270, 1308, 1412, 1524, 1753, 1788], 'Cell.': [352, 394, 432, 469, 773, 799, 823, 932, 1002, 1239, 1281, 1319, 1356, 1661, 1687, 1711, 1820, 1891], 'Biochem.': [353, 1240], '62:': [355, 1242], '149-157Crossref': [356, 1243], '(43)': [359, 1246], 'Scholar).': [361, 589, 733, 836, 945, 1011, 1248, 1394, 1477, 1621, 1724, 1833, 1872, 1900], 'Nuclear': [362, 1249], 'acetyltransferases': [364, 1251], 'such': [365, 1252], 'as': [366, 706, 743, 1253, 1594, 1631], 'factors': [368, 1255], 'GCN5,': [369, 1256], 'PCAF,': [370, 1257], 'p300/CBP,': [371, 1258], 'TAFII230/250': [373, 1260], 'identified': [376, 693, 990, 1023, 1263, 1581, 1879, 1912], 'from': [377, 1264], 'organisms': [379, 1266], '(5Brownell': [380, 1267], 'Zhou': [382, 1269], 'Ranalli': [384, 489, 1271, 1376], 'T.': [385, 413, 419, 427, 449, 855, 1272, 1300, 1306, 1314, 1336, 1743], 'Kobayashi': [386, 567, 1273, 1455], 'R.': [387, 568, 816, 896, 1274, 1456, 1704, 1784], 'Edmondson': [388, 493, 1275, 1380], 'D.G.': [389, 494, 1276, 1381], 'Roth': [390, 495, 1277, 1382], 'S.Y.': [391, 496, 965, 1278, 1383, 1853], '84:': [396, 1283], '843-851Abstract': [397, 1284], '(1277)': [405, 1292], '6Mizzen': [408, 1295], 'C.A.': [409, 526, 638, 764, 925, 1296, 1414, 1526, 1652, 1813], 'Yang': [410, 789, 866, 1297, 1677, 1754, 2034], 'X.-J.': [411, 1298], 'Kokubo': [412, 1299], 'Brownell': [414, 485, 1301, 1372], 'Bannister': [416, 1303], 'A.J.': [417, 447, 1304, 1334], 'Owen-Hughes': [418, 1305], 'Workman': [420, 1307], 'Wang': [422, 1309], 'L.': [423, 894, 902, 917, 1310, 1782, 1790, 1805], 'Berger': [424, 1311], 'S.L.': [425, 528, 640, 770, 929, 1312, 1416, 1528, 1658, 1817], 'Kouzarides': [426, 448, 1313, 1335], 'Nakatani': [428, 467, 1315, 1354], 'Y.': [429, 468, 543, 714, 814, 1316, 1355, 1431, 1602, 1702], '87:': [434, 471, 1321, 1358], '1261-1270Abstract': [435, 1322], '(617)': [443, 1330], '7Bannister': [446, 1333], 'Nature.': [450, 499, 884, 907, 1039, 1337, 1386, 1772, 1795, 1928], '384:': [452, 1041, 1339, 1930], '641-643Crossref': [453, 1340], '(1523)': [456, 1343], '8Ogryzko': [459, 1346], 'V.V.': [460, 1347], 'Schiltz': [461, 1348], 'R.L.': [462, 1349], 'Russanova': [463, 1350], 'V.': [464, 1351], 'Howard': [465, 1352], 'B.H.': [466, 1353], '953-959Abstract': [472, 1359], '(2368)': [480, 1367], '9Kuo': [483, 1370], 'M.H.': [484, 1371], 'Sobel': [487, 1374], 'R.E.': [488, 1375], 'T.A.': [490, 1377], 'Cook': [491, 1378], 'R.G.': [492, 1379], '383:': [501, 1388], '269-272Crossref': [502, 1389], '(503)': [505, 1392], 'Scholar).Several': [507], 'yeast': [508, 617, 660, 690, 697, 985, 1018, 1396, 1505, 1548, 1578, 1585, 1874, 1907], 'mammalian': [510, 1398], 'deacetylases': [512, 1400], 'identified,': [515, 1403], 'their': [517, 1405], 'corresponding': [518, 1406], 'genes': [519, 1407], '(10Taunton': [523, 635, 1411, 1523], 'Hassig': [525, 637, 924, 1413, 1525, 1812], 'Schreiber': [527, 639, 769, 928, 1415, 1527, 1657, 1816], '408-411Crossref': [532, 644, 1420, 1532], '(1524)': [535, 647, 1423, 1535], '11Yang': [538, 1426], 'W.-M.': [539, 710, 790, 1427, 1598, 1678], 'Inouye': [540, 711, 1428, 1599], 'C.': [541, 712, 1066, 1429, 1600, 1955], 'Zeng': [542, 713, 1430, 1601], 'Bearss': [544, 715, 1432, 1603], 'D.': [545, 716, 822, 921, 1028, 1032, 1433, 1604, 1710, 1809, 1917, 1921], 'Seto': [546, 717, 795, 874, 1434, 1605, 1683, 1762], 'E.': [547, 718, 796, 875, 1435, 1606, 1684, 1763], 'Proc.': [548, 575, 719, 970, 1436, 1463, 1607, 1858], 'Natl.': [549, 576, 720, 971, 1437, 1464, 1608, 1859], 'Acad.': [550, 577, 721, 972, 1438, 1465, 1609, 1860], 'Sci.': [551, 578, 722, 973, 1439, 1466, 1610, 1861], 'U.': [552, 579, 723, 974, 1440, 1467, 1611, 1862], 'S.': [553, 564, 570, 580, 724, 975, 1030, 1441, 1452, 1458, 1468, 1612, 1863, 1919], 'A.': [554, 581, 725, 976, 1442, 1469, 1613, 1864], '93:': [556, 583, 727, 1444, 1471, 1615], '12845-12850Crossref': [557, 728, 1445, 1616], '(482)': [560, 731, 1448, 1619], '12Rundlett': [563, 1451], 'Carmen': [565, 1453], 'A.A.': [566, 1454], 'Bavykin': [569, 1457], 'Turner': [571, 1459], 'B.M.': [572, 1460], 'Grunstein': [573, 1461], 'M.': [574, 861, 998, 1462, 1749, 1887], '14503-14508Crossref': [584, 1472], '(516)': [587, 1475], 'In': [590, 837, 1478, 1725], 'yeast,': [591, 1479], 'HDA1': [593, 1481], 'which': [595, 1483], 'shares': [596, 1484], 'similarity': [598, 1486], 'RPD3,': [600, 1488], 'subunit': [603, 1491], 'large': [606, 1121, 1494, 2010], 'complex': [609, 620, 753, 1122, 1497, 1508, 1641, 2011], 'HDA.': [610, 1498], 'RPD3': [611, 691, 986, 1019, 1499, 1579, 1875, 1908], 'associated': [614, 1502], 'another': [616, 1504], 'HDB.': [621, 1509], 'Using': [622, 1510], 'trapoxin': [624, 1512], '(an': [625, 1513], 'inhibitor': [626, 1514], 'deacetylase)': [629, 1517], 'affinity': [630, 1518], 'matrix,': [631, 1519], 'Taunton': [632, 1520], 'et': [633, 1521], 'al.': [634, 1522], 'Scholar)': [649, 1537], 'purified': [650, 1538], '55-kDa': [655, 666, 1543, 1554], 'related': [657, 1545], 'RPD3.': [662, 1550], 'Immunoprecipitation': [663, 1551], 'this': [665, 1553], '(also': [669, 1557], 'called': [670, 1558], 'HD1),': [671, 1559], 'showed': [672, 1560], 'that': [673, 952, 1097, 1115, 1123, 1561, 1840, 1986, 2004, 2012], 'contains': [675, 1098, 1563, 1987], 'activity.': [678, 1101, 1566, 1990], 'A': [679, 1567], 'second': [680, 1568], 'high': [687, 1575], 'homology': [688, 1576], 'was': [692, 988, 1580, 1877], 'based': [694, 1582], 'on': [695, 1583], 'two-hybrid': [698, 1586], 'trap': [699, 1587], 'experiment': [700, 1588], 'YY1': [703, 734, 1591, 1622], 'bait': [708, 1596], '(11Yang': [709, 1597], 'negatively': [735, 1623], 'regulates': [736, 1624], 'tethering': [739, 1627], 'corepressor.': [745, 1633], 'Both': [746, 1634], 'exist': [750, 1638], 'corepressor': [756, 1644], 'mSIN3': [757, 1645], 'mediate': [759, 1647], 'Mad': [760, 1648], 'repression': [762, 1129, 1650, 2018], '(13Hassig': [763, 1651], 'Fleischer': [765, 1653], 'T.C.': [766, 1654], 'Billin': [767, 1655], 'A.N.': [768, 1656], 'Ayer': [771, 926, 1659, 1814], 'D.E.': [772, 927, 1660, 1815], '89:': [775, 801, 825, 934, 1663, 1689, 1713, 1822], '341-347Abstract': [776, 1664], '(656)': [784, 1672], '14Laherty': [787, 1675], 'Sun': [791, 1679], 'J.-M.': [792, 1680], 'Davie': [793, 872, 1681, 1760], 'Eisenman': [797, 876, 1685, 1764], 'R.N.': [798, 877, 1686, 1765], '349-356Abstract': [802, 1690], '(837)': [810, 1698], '15Zhang': [813, 1701], 'Iratni': [815, 1703], 'Erdjument-Bromage': [817, 1705], 'H.': [818, 898, 1706, 1786], 'Tempst': [819, 1707], 'P.': [820, 1038, 1708, 1927], 'Reinberg': [821, 1709], '357-364Abstract': [826, 1714], '(498)': [834, 1722], 'addition,': [838, 1726], 'are': [842, 1730], 'essential': [843, 1731], 'components': [844, 1732], 'two': [846, 1734], 'thyroid': [847, 1735], 'hormone': [848, 1736], 'receptor': [849, 957, 1737, 1845], 'corepressors,': [850, 1738], 'N-CoR': [851, 1739], 'SMRT': [853, 1741], '(16Heinzel': [854, 1742], 'Lavinsky': [856, 1744], 'R.M.': [857, 931, 1745, 1819], 'Mullen': [858, 1746], 'T.-M.': [859, 1747], 'Soderstrom': [860, 1748], 'Laherty': [862, 1750], 'Torchia': [864, 1752], 'W.M.': [867, 1755], 'Brard': [868, 1756], 'G.': [869, 959, 1034, 1757, 1847, 1923], 'Ngo': [870, 1758], 'S.D.': [871, 1759], 'Rose': [878, 1766], 'D.W.': [879, 1767], 'Glass': [880, 1768], 'C.K.': [881, 1769], 'Rosenfeld': [882, 1770], 'M.G.': [883, 1771], '387:': [886, 909, 1774, 1797], '43-48Crossref': [887, 1775], '(1079)': [890, 1778], '17Alland': [893, 1781], 'Muhle': [895, 1783], 'Hou': [897, 1785], 'Potes': [899, 1787], 'Chin': [901, 1789], 'Schreiber-Agus': [903, 1791], 'N.': [904, 1792], 'DePinho': [905, 1793], 'R.A.': [906, 1794], '49-55Crossref': [910, 1798], '(733)': [913, 1801], '18Nagy': [916, 1804], 'Kao': [918, 1806], 'H.Y.': [919, 1807], 'Chakravarti': [920, 1808], 'Lin': [922, 1810], 'R.J.': [923, 1811], 'Evans': [930, 1818], '373-380Abstract': [935, 1823], '(1101)': [943, 1831], 'important': [950, 1838], 'transactivation': [954, 1842], 'progesterone': [956, 1844], '(19Jenster': [958, 1846], 'Spencer': [960, 1848], 'T.E.': [961, 1849], 'Burcin': [962, 1850], 'M.M.': [963, 1851], 'Tsai': [964, 966, 1852, 1854], 'M.-J.': [967, 1855], "O'Malley": [968, 1856], 'B.W.': [969, 1857], '94:': [978, 1866], '7879-7884Crossref': [979, 1867], '(231)': [982, 1870], 'Scholar).The': [984], 'originally': [989, 1878], 'genetic': [992, 1881], 'screens': [993, 1882], 'for': [994, 1883, 2039, 2052], 'repressors': [996, 1885], '(20Vidal': [997, 1886], 'Gaber': [999, 1888], 'R.F.': [1000, 1889], 'Mol.': [1001, 1890], '1991;': [1004, 1893], '11:': [1005, 1894], '6317-6327Crossref': [1006, 1895], '(261)': [1009, 1898], 'Besides': [1012, 1901], 'mouse,': [1015, 1904], 'highly': [1016, 1905], 'homologous': [1017, 1906], 'sequences': [1020, 1909], 'inDrosophila': [1024, 1913], '(21Rubertis': [1025, 1914], 'F.D.': [1026, 1915], 'Kadosh': [1027, 1916], 'Henchoz': [1029, 1918], 'Pauli': [1031, 1920], 'Reuter': [1033, 1922], 'Struhl': [1035, 1924], 'K.': [1036, 1925], 'Spierer': [1037, 1926], '589-591Crossref': [1042, 1931], '(194)': [1045, 1934], 'Scholar),': [1047, 1936], 'Caenorhabditis': [1048, 1937], 'elegans': [1049, 1067, 1938, 1956], '(X78454': [1050, 1939], '1176665),': [1052, 1941], 'Xenopus': [1054, 1943], 'laevis': [1055, 1069, 1944, 1958], '(gi:576995).': [1056, 1945], 'Currently,': [1057, 1946], 'has': [1059, 1948], 'not': [1060, 1949], 'yet': [1061, 1950], 'established': [1063, 1952], 'whether': [1064, 1077, 1953, 1966], 'orX.': [1068, 1957], 'RPD3-related': [1070, 1094, 1959, 1983], 'proteins': [1071, 1960], 'activities': [1075, 1964], 'they': [1078, 1967], 'play': [1079, 1968], 'role': [1081, 1970], 'repression.': [1084, 1973], 'Here,': [1085, 1974], 'we': [1086, 1975], 'describe': [1087, 1976], 'identification': [1089, 1978], 'third': [1092, 1981], 'Like': [1102, 1991], 'YY1,': [1113, 2002], 'suggesting': [1114, 2003], 'may': [1117, 2006], 'participate': [1118, 2007], 'mediates': [1124, 2013], 'wide': [1126, 2015], 'variety': [1127, 2016], 'systems': [1130, 2019], 'human.': [1132, 2021], 'We': [2022], 'thank': [2023], 'Mon-Li': [2024], 'Chu,': [2025], 'Chris': [2026], 'Hassig,': [2027], 'Wen-Hwa': [2028], 'Lee,': [2029], 'Ivan': [2030], 'Sadowski,': [2031], 'Stuart': [2032], 'Schreiber,': [2033], 'Shi,': [2035], 'Xueliang': [2037], 'Zhu': [2038], 'generous': [2040], 'gifts': [2041], 'plasmids': [2043], 'libraries': [2045], 'Nancy': [2047], 'Olashaw': [2048], 'Tere': [2050], 'Munoz-Antonia': [2051], 'discussion': [2053], 'critical': [2055], 'manuscript.': [2059]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2063460322', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 18}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2024-12-11T20:48:13.657856', 'created_date': '2016-06-24'}