Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2059460950', 'doi': 'https://doi.org/10.1097/00006534-199809040-00014', 'title': 'Toxic Epidermal Necrolysis Syndrome: Mortality Rate Reduced with Early Referral to Regional Burn Center', 'display_name': 'Toxic Epidermal Necrolysis Syndrome: Mortality Rate Reduced with Early Referral to Regional Burn Center', 'publication_year': 1998, 'publication_date': '1998-09-01', 'ids': {'openalex': 'https://openalex.org/W2059460950', 'doi': 'https://doi.org/10.1097/00006534-199809040-00014', 'mag': '2059460950', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9734418'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00006534-199809040-00014', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100736837', 'display_name': 'Plastic & Reconstructive Surgery', 'issn_l': '0032-1052', 'issn': ['0032-1052', '1076-5751', '1529-4242'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5112524033', 'display_name': 'Tim McGee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}, {'id': 'https://openalex.org/I2802697821', 'display_name': 'Johns Hopkins Bayview Medical Center', 'ror': 'https://ror.org/04pwc8466', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436', 'https://openalex.org/I2802697821']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tim McGee', 'raw_affiliation_strings': ['Baltimore Regional Burn Center', 'Johns Hopkins Bayview Medical Center', 'revised November 10, 1997.', 'the Baltimore Regional Burn Center at Johns Hopkins Bayview Medical Center. Received for publication July 18, 1997'], 'affiliations': [{'raw_affiliation_string': 'the Baltimore Regional Burn Center at Johns Hopkins Bayview Medical Center. Received for publication July 18, 1997', 'institution_ids': ['https://openalex.org/I145311948', 'https://openalex.org/I2802697821']}, {'raw_affiliation_string': 'Johns Hopkins Bayview Medical Center', 'institution_ids': ['https://openalex.org/I145311948', 'https://openalex.org/I2802697821']}, {'raw_affiliation_string': 'Baltimore Regional Burn Center', 'institution_ids': []}, {'raw_affiliation_string': 'revised November 10, 1997.', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113500398', 'display_name': 'Andrew M. Munster', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}, {'id': 'https://openalex.org/I2802697821', 'display_name': 'Johns Hopkins Bayview Medical Center', 'ror': 'https://ror.org/04pwc8466', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436', 'https://openalex.org/I2802697821']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew Munster', 'raw_affiliation_strings': ['Baltimore Regional Burn Center', 'Johns Hopkins Bayview Medical Center', 'revised November 10, 1997.', 'the Baltimore Regional Burn Center at Johns Hopkins Bayview Medical Center. Received for publication July 18, 1997'], 'affiliations': [{'raw_affiliation_string': 'the Baltimore Regional Burn Center at Johns Hopkins Bayview Medical Center. Received for publication July 18, 1997', 'institution_ids': ['https://openalex.org/I145311948', 'https://openalex.org/I2802697821']}, {'raw_affiliation_string': 'Johns Hopkins Bayview Medical Center', 'institution_ids': ['https://openalex.org/I145311948', 'https://openalex.org/I2802697821']}, {'raw_affiliation_string': 'revised November 10, 1997.', 'institution_ids': []}, {'raw_affiliation_string': 'Baltimore Regional Burn Center', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.553, 'has_fulltext': False, 'cited_by_count': 147, 'citation_normalized_percentile': {'value': 0.936154, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '102', 'issue': '4', 'first_page': '1018', 'last_page': '1022'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11117', 'display_name': 'Drug-Induced Adverse Reactions', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11117', 'display_name': 'Drug-Induced Adverse Reactions', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12438', 'display_name': 'Urticaria and Related Conditions', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11730', 'display_name': 'Autoimmune Bullous Skin Diseases', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/toxic-epidermal-necrolysis', 'display_name': 'Toxic Epidermal Necrolysis', 'score': 0.9737276}, {'id': 'https://openalex.org/keywords/burn-center', 'display_name': 'Burn center', 'score': 0.8188789}], 'concepts': [{'id': 'https://openalex.org/C2780664588', 'wikidata': 'https://www.wikidata.org/wiki/Q1878682', 'display_name': 'Toxic epidermal necrolysis', 'level': 2, 'score': 0.9737276}, {'id': 'https://openalex.org/C2778838822', 'wikidata': 'https://www.wikidata.org/wiki/Q2151257', 'display_name': 'Burn center', 'level': 3, 'score': 0.8188789}, {'id': 'https://openalex.org/C2776135927', 'wikidata': 'https://www.wikidata.org/wiki/Q5242559', 'display_name': 'Referral', 'level': 2, 'score': 0.6720507}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6632309}, {'id': 'https://openalex.org/C179755657', 'wikidata': 'https://www.wikidata.org/wiki/Q58702', 'display_name': 'Mortality rate', 'level': 2, 'score': 0.5000291}, {'id': 'https://openalex.org/C16005928', 'wikidata': 'https://www.wikidata.org/wiki/Q171171', 'display_name': 'Dermatology', 'level': 1, 'score': 0.47868925}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.37615597}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.34086844}, {'id': 'https://openalex.org/C194828623', 'wikidata': 'https://www.wikidata.org/wiki/Q2861470', 'display_name': 'Emergency medicine', 'level': 1, 'score': 0.3128141}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.25653416}, {'id': 'https://openalex.org/C3017944768', 'wikidata': 'https://www.wikidata.org/wiki/Q1450463', 'display_name': 'Poison control', 'level': 2, 'score': 0.09836799}, {'id': 'https://openalex.org/C512399662', 'wikidata': 'https://www.wikidata.org/wiki/Q3505712', 'display_name': 'Family medicine', 'level': 1, 'score': 0.08870256}], 'mesh': [{'descriptor_ui': 'D012017', 'descriptor_name': 'Referral and Consultation', 'qualifier_ui': 'Q000706', 'qualifier_name': 'statistics & numerical data', 'is_major_topic': True}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015142', 'descriptor_name': 'Baltimore', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002053', 'descriptor_name': 'Burn Units', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002423', 'descriptor_name': 'Cause of Death', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003131', 'descriptor_name': 'Combined Modality Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006875', 'descriptor_name': 'Hydrotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012017', 'descriptor_name': 'Referral and Consultation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016038', 'descriptor_name': 'Skin Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015996', 'descriptor_name': 'Survival Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00006534-199809040-00014', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100736837', 'display_name': 'Plastic & Reconstructive Surgery', 'issn_l': '0032-1052', 'issn': ['0032-1052', '1076-5751', '1529-4242'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9734418', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.9, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1982750066', 'https://openalex.org/W1983504482', 'https://openalex.org/W1992848614', 'https://openalex.org/W1994294391', 'https://openalex.org/W1996028550', 'https://openalex.org/W2031069132', 'https://openalex.org/W2031745728', 'https://openalex.org/W2040099759', 'https://openalex.org/W2045391651', 'https://openalex.org/W2051501191', 'https://openalex.org/W2087482037', 'https://openalex.org/W2091504262', 'https://openalex.org/W2092858046', 'https://openalex.org/W2108224331', 'https://openalex.org/W2132871515', 'https://openalex.org/W2317624504', 'https://openalex.org/W2318665922', 'https://openalex.org/W2400231767', 'https://openalex.org/W2408076721', 'https://openalex.org/W2467789117', 'https://openalex.org/W4230715711', 'https://openalex.org/W4231595562', 'https://openalex.org/W4231616044', 'https://openalex.org/W4233314680', 'https://openalex.org/W4240967189', 'https://openalex.org/W4247701171', 'https://openalex.org/W4254945325'], 'related_works': ['https://openalex.org/W3189834894', 'https://openalex.org/W3023850836', 'https://openalex.org/W3017824371', 'https://openalex.org/W2735354031', 'https://openalex.org/W2619480515', 'https://openalex.org/W2585139052', 'https://openalex.org/W2389651796', 'https://openalex.org/W2089965922', 'https://openalex.org/W2039187204', 'https://openalex.org/W2000380539'], 'abstract_inverted_index': {'Toxic': [0], 'epidermal': [1, 32, 260], 'necrolysis': [2, 33, 261], 'syndrome': [3], 'is': [4, 251, 271], 'an': [5, 67], 'uncommon,': [6], 'acute,': [7], 'life-threatening': [8], 'disorder': [9], 'that': [10, 79], 'involves': [11], 'sloughing': [12], 'of': [13, 51, 55, 59, 69, 75, 114, 116, 127, 131, 137, 156, 161, 179, 181, 196, 198, 209, 213, 220, 222, 256, 266], 'skin': [14], 'at': [15, 35], 'the': [16, 36, 56, 76, 104, 112, 157, 162, 182, 199, 223, 254], 'dermal-epidermal': [17], 'junction': [18], 'with': [19, 185, 202, 258, 274], 'associated': [20], 'mucositis.': [21], 'Between': [22], '1985': [23], 'and': [24, 171, 269], '1995,': [25], '36': [26, 158], 'patients': [27, 57, 80, 105, 168, 183, 200, 224, 257], 'were': [28, 61, 106, 149, 226], 'treated': [29], 'for': [30, 139, 154, 205], 'toxic': [31, 259], 'syndrome,': [34], 'Baltimore': [37], 'Regional': [38], 'Burn': [39], 'Center.': [40], 'A': [41], 'retrospective': [42], 'chart': [43], 'analysis': [44], 'was': [45], 'performed': [46], 'to': [47, 247, 253, 279], 'discover': [48], 'significant': [49], 'determinants': [50], 'mortality.': [52], 'Ninety-seven': [53], 'percent': [54, 129, 135, 177, 194, 211, 218], '(35': [58], '36)': [60], 'referred': [62, 85, 119, 141, 184, 201, 227], 'from': [63, 151, 165], 'outside': [64, 243], 'institutions': [65, 153], 'after': [66], 'average': [68], '6.3': [70], '±': [71, 92, 97], '0.8': [72], 'days.': [73], 'Analysis': [74, 160], 'data': [77, 164], 'shows': [78], 'who': [81, 225], 'survived': [82], 'had': [83, 123, 231], 'been': [84], '7.5': [86], 'days': [87, 94], 'earlier': [88], 'than': [89], 'nonsurvivors': [90], '(4.0': [91], '0.5': [93], 'versus': [95, 133], '11.5': [96], '1.4': [98], 'days,': [99], 'p': [100], '<': [101, 146], '0.001).': [102, 147], 'When': [103], 'separated': [107], 'into': [108], 'two': [109], 'groups': [110], 'on': [111, 234], 'basis': [113], 'time': [115], 'referral,': [117], 'those': [118, 140], '"early"': [120], '(≤7': [121, 276], 'days)': [122, 144, 230, 277], 'a': [124, 206, 248, 280], 'mortality': [125, 207, 270], 'rate': [126, 208, 265], '4': [128], '(1': [130, 212], '24)': [132], '83': [134], '(10': [136], '12)': [138], '"late"': [142], '(>7': [143, 229], '(p': [145], 'Data': [148], 'available': [150], 'transferring': [152], '21': [155, 167], 'patients.': [159], 'microbiologic': [163], 'these': [166], 'revealed': [169], 'bacteremia,': [170, 267], 'subsequent': [172], 'death': [173], 'occurred': [174], 'in': [175, 191, 242], '100': [176], '(6': [178, 219], '6)': [180], 'positive': [186, 232], 'cultures,': [187, 204], 'whereas': [188], 'bacteremia': [189], 'developed': [190], 'only': [192], '33': [193], '(5': [195], '15)': [197], 'negative': [203], '7': [210], '15).': [214], 'In': [215], 'addition,': [216], '86': [217], '7)': [221], 'late': [228], 'cultures': [233], 'referral.': [235], 'The': [236, 263], 'current': [237], 'trend': [238], 'toward': [239], 'prolonged': [240], 'treatment': [241], 'facilities': [244], 'before': [245], 'referral': [246, 278], 'burn': [249, 282], 'center': [250], 'detrimental': [252], 'care': [255], 'syndrome.': [262], 'overall': [264], 'septicemia,': [268], 'significantly': [272], 'reduced': [273], 'early': [275], 'regional': [281], 'center.': [283], '(Plast.': [284], 'Reconstr.': [285], 'Surg.': [286], '102:': [287], '1018,': [288], '1998.)': [289]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059460950', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-21T16:55:04.925491', 'created_date': '2016-06-24'}