Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2032109763', 'doi': 'https://doi.org/10.1212/wnl.52.7.1338', 'title': 'A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children', 'display_name': 'A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children', 'publication_year': 1999, 'publication_date': '1999-04-01', 'ids': {'openalex': 'https://openalex.org/W2032109763', 'doi': 'https://doi.org/10.1212/wnl.52.7.1338', 'mag': '2032109763', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10227615'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.52.7.1338', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5006231598', 'display_name': 'Roy D. Elterman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}, {'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}, {'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R.D. Elterman', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}, {'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}, {'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002880520', 'display_name': 'Tracy A. Glauser', 'orcid': 'https://orcid.org/0000-0003-1520-2732'}, 'institutions': [{'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}, {'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}, {'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T.A. Glauser', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}, {'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062982325', 'display_name': 'Elaine Wyllie', 'orcid': 'https://orcid.org/0000-0002-0864-6645'}, 'institutions': [{'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}, {'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}, {'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'E. Wyllie', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}, {'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017945392', 'display_name': 'R. Reife', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}, {'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}, {'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R. Reife', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}, {'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}, {'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037516355', 'display_name': 'Shu‐Chen Wu', 'orcid': 'https://orcid.org/0000-0001-5981-674X'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}, {'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}, {'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S.-C. Wu', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}, {'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}, {'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037632361', 'display_name': 'Gordon Pledger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}, {'id': 'https://openalex.org/I4210133182', 'display_name': 'Dallas Nephrology Associates', 'ror': 'https://ror.org/045jrd330', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133182']}, {'id': 'https://openalex.org/I1330063522', 'display_name': 'Johnson & Johnson (United States)', 'ror': 'https://ror.org/03qd7mz70', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1330063522']}, {'id': 'https://openalex.org/I1285204247', 'display_name': "Cincinnati Children's Hospital Medical Center", 'ror': 'https://ror.org/01hcyya48', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1285204247']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'G. Pledger', 'raw_affiliation_strings': ['Cleveland Clinic Foundation (Dr. Wyllie), OH', 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'the Topiramate YP Study Group.'], 'affiliations': [{'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX; Division of Pediatric Neurology (Dr. Glauser), Children’s Hospital Medical Center, Cincinnati, OH; Cleveland Clinic Foundation (Dr. Wyllie), OH; Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ; The R.W. Johnson Pharmaceutical Research Institute (Drs. Wu and Pledger), Raritan, NJ; and the Topiramate YP Study Group.', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'From the Dallas Pediatric Neurology Associates (Dr. Elterman)Dallas, TX', 'institution_ids': ['https://openalex.org/I4210133182']}, {'raw_affiliation_string': 'Corporate Office Science and Technology (Dr. Reife), Johnson & Johnson, New Brunswick, NJ', 'institution_ids': ['https://openalex.org/I1330063522']}, {'raw_affiliation_string': 'Cleveland Clinic Foundation (Dr. Wyllie), OH', 'institution_ids': ['https://openalex.org/I1316902750']}, {'raw_affiliation_string': 'the Topiramate YP Study Group.', 'institution_ids': []}, {'raw_affiliation_string': "Division of Pediatric Neurology (Dr. Glauser), Children's Hospital Medical Center, Cincinnati, OH", 'institution_ids': ['https://openalex.org/I1285204247']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 12.989, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 235, 'citation_normalized_percentile': {'value': 0.999799, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '52', 'issue': '7', 'first_page': '1338', 'last_page': '1338'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10094', 'display_name': 'Epilepsy and Seizures', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10094', 'display_name': 'Epilepsy and Seizures', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12229', 'display_name': 'Prenatal Exposure to Antiepileptic Drugs', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10429', 'display_name': 'Brain-Computer Interfaces in Neuroscience and Medicine', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/seizures', 'display_name': 'Seizures', 'score': 0.523599}], 'concepts': [{'id': 'https://openalex.org/C2777683783', 'wikidata': 'https://www.wikidata.org/wiki/Q221174', 'display_name': 'Topiramate', 'level': 3, 'score': 0.93068165}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.7155601}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6510806}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.6042669}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.5348538}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.5074753}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.43914267}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40084007}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.34787455}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.10173878}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D004828', 'descriptor_name': 'Epilepsies, Partial', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D005632', 'descriptor_name': 'Fructose', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004828', 'descriptor_name': 'Epilepsies, Partial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005632', 'descriptor_name': 'Fructose', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D005632', 'descriptor_name': 'Fructose', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D005632', 'descriptor_name': 'Fructose', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D005632', 'descriptor_name': 'Fructose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077236', 'descriptor_name': 'Topiramate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.52.7.1338', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10227615', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.63}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1964100346', 'https://openalex.org/W1980866137', 'https://openalex.org/W1983439863', 'https://openalex.org/W2004951945', 'https://openalex.org/W2012891482', 'https://openalex.org/W2019124159', 'https://openalex.org/W2043242122', 'https://openalex.org/W2114002180', 'https://openalex.org/W2117449343', 'https://openalex.org/W2129745199', 'https://openalex.org/W2150290224', 'https://openalex.org/W2171332093', 'https://openalex.org/W2797177778', 'https://openalex.org/W4214928337', 'https://openalex.org/W4236676256', 'https://openalex.org/W4239594659', 'https://openalex.org/W4253837878'], 'related_works': ['https://openalex.org/W53449851', 'https://openalex.org/W2884631023', 'https://openalex.org/W2353505721', 'https://openalex.org/W2351548256', 'https://openalex.org/W2349217635', 'https://openalex.org/W2118566923', 'https://openalex.org/W2085830368', 'https://openalex.org/W2074860758', 'https://openalex.org/W1992751297', 'https://openalex.org/W1968165247'], 'abstract_inverted_index': {'<b><i>Objective:</i></b>': [0], 'To': [1], 'evaluate': [2], 'the': [3, 47, 197, 210], 'efficacy': [4], 'and': [5, 119, 139, 169, 207], 'safety': [6], 'of': [7, 96, 108, 113, 128, 133, 144, 212], 'topiramate': [8, 55], '6': [9], 'mg/kg/day': [10], 'in': [11, 31, 78, 146, 191, 209, 215], 'children': [12], '(age': [13], '2': [14], 'to': [15, 200], '16': [16, 65, 107], 'years)': [17], 'as': [18], 'adjunctive': [19], 'therapy': [20], 'for': [21, 64], 'uncontrolled': [22], 'partial-onset': [23, 44, 81, 213], 'seizures': [24, 30, 45, 214], 'with': [25, 40, 53, 101, 121, 162], 'or': [26, 59, 164, 189], 'without': [27], 'secondarily': [28], 'generalized': [29], 'a': [32, 71, 93, 102, 122], 'multicenter,': [33], 'randomized,': [34], 'double-blind,': [35], 'placebo-controlled': [36], 'trial.': [37], '<b><i>Methods:</i></b>': [38], 'Patients': [39], 'at': [41], 'least': [42], 'six': [43], 'during': [46], '8-week': [48], 'baseline': [49, 77], 'phase': [50], 'were': [51, 175, 187], 'treated': [52], 'either': [54], '(n': [56, 61], '=': [57, 62, 91, 117, 137, 150], '41)': [58], 'placebo': [60], '45)': [63], 'weeks.': [66], '<b><i>Results:</i></b>': [67], 'Topiramate-treated': [68], 'patients': [69, 86, 100, 120, 195], 'had': [70], 'greater': [72, 94], 'median': [73], 'percent': [74], 'reduction': [75, 126], 'from': [76], 'average': [79], 'monthly': [80], 'seizure': [82, 104, 124, 147], 'rate': [83, 105, 125], 'than': [84, 180], 'placebo-treated': [85, 181], '(33.1%': [87], 'versus': [88, 111, 131, 155, 159, 167, 173], '10.5%,': [89], '<i>p</i>': [90, 116, 136], '0.034),': [92], 'proportion': [95], 'treatment': [97, 211], 'responders': [98], '(i.e.,': [99], '≥50%': [103], 'reduction;': [106], '41': [109, 129], '[39%]': [110], '9': [112], '45': [114, 134], '[20%],': [115], '0.080),': [118], '≥75%': [123], '(7': [127], '[17%]': [130], '1': [132], '[2%],': [135], '0.019),': [138], 'better': [140], 'parental': [141], 'global': [142], 'evaluations': [143], 'improvement': [145], 'severity': [148], '(<i>p</i>': [149], '0.019).': [151], 'Emotional': [152], 'lability': [153], '(12%': [154, 166], '4%),': [156], 'fatigue': [157], '(15%': [158], '7%),': [160], 'difficulty': [161], 'concentration': [163], 'attention': [165], '2%),': [168], 'forgetfulness/impaired': [170], 'memory': [171], '(7%': [172], '0%)': [174], 'more': [176], 'frequent': [177], 'among': [178], 'topiramate-treated': [179, 194], 'patients.': [182], 'Most': [183], 'treatment-emergent': [184], 'adverse': [185, 201], 'events': [186], 'mild': [188], 'moderate': [190], 'severity.': [192], 'No': [193], 'discontinued': [196], 'study': [198], 'due': [199], 'events.': [202], '<b><i>Conclusions:</i></b>': [203], 'Topiramate': [204], 'was': [205], 'safe': [206], 'effective': [208], 'children.': [216]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2032109763', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-09-26T09:57:58.295105', 'created_date': '2016-06-24'}