Publication Information

{'id': 'https://openalex.org/W2015164139', 'doi': 'https://doi.org/10.1016/j.cbpa.2007.02.025', 'title': 'Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family', 'display_name': 'Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family', 'publication_year': 2007, 'publication_date': '2007-04-01', 'ids': {'openalex': 'https://openalex.org/W2015164139', 'doi': 'https://doi.org/10.1016/j.cbpa.2007.02.025', 'mag': '2015164139', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17353140'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cbpa.2007.02.025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S35563517', 'display_name': 'Current Opinion in Chemical Biology', 'issn_l': '1367-5931', 'issn': ['1367-5931', '1879-0402'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033584391', 'display_name': 'Rainer Stuermer', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Rainer Stuermer', 'raw_affiliation_strings': ['BASF AG, GVF/E-B9, D-67056 Ludwigshafen, Germany.'], 'affiliations': [{'raw_affiliation_string': 'BASF AG, GVF/E-B9, D-67056 Ludwigshafen, Germany.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012903224', 'display_name': 'Bernhard Hauer', 'orcid': 'https://orcid.org/0000-0001-6259-3348'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Bernhard Hauer', 'raw_affiliation_strings': ['BASF AG, GVF/E-B9, D-67056 Ludwigshafen, Germany.'], 'affiliations': [{'raw_affiliation_string': 'BASF AG, GVF/E-B9, D-67056 Ludwigshafen, Germany.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042254098', 'display_name': 'Mélanie Hall', 'orcid': 'https://orcid.org/0000-0003-4539-1992'}, 'institutions': [{'id': 'https://openalex.org/I15766117', 'display_name': 'University of Graz', 'ror': 'https://ror.org/01faaaf77', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I15766117']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Melanie Hall', 'raw_affiliation_strings': ['Department of Chemistry, Organic & Bioorganic Chemistry University of Graz Heinrichstrasse 28 A-8010 Graz Austria'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Organic & Bioorganic Chemistry University of Graz Heinrichstrasse 28 A-8010 Graz Austria', 'institution_ids': ['https://openalex.org/I15766117']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052784808', 'display_name': 'Kurt Faber', 'orcid': 'https://orcid.org/0000-0003-0497-5430'}, 'institutions': [{'id': 'https://openalex.org/I15766117', 'display_name': 'University of Graz', 'ror': 'https://ror.org/01faaaf77', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I15766117']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Kurt Faber', 'raw_affiliation_strings': ['Department of Chemistry, Organic & Bioorganic Chemistry University of Graz Heinrichstrasse 28 A-8010 Graz Austria'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Organic & Bioorganic Chemistry University of Graz Heinrichstrasse 28 A-8010 Graz Austria', 'institution_ids': ['https://openalex.org/I15766117']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4660, 'currency': 'USD', 'value_usd': 4660, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.437, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 316, 'citation_normalized_percentile': {'value': 0.979798, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '11', 'issue': '2', 'first_page': '203', 'last_page': '213'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13561', 'display_name': 'Deuterium Incorporation in Pharmaceutical Research', 'score': 0.9818, 'subfield': {'id': 'https://openalex.org/subfields/3003', 'display_name': 'Pharmaceutical Science'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13561', 'display_name': 'Deuterium Incorporation in Pharmaceutical Research', 'score': 0.9818, 'subfield': {'id': 'https://openalex.org/subfields/3003', 'display_name': 'Pharmaceutical Science'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10404', 'display_name': 'Enzyme Immobilization Techniques', 'score': 0.9814, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10375', 'display_name': 'Drug Metabolism and Pharmacogenomics', 'score': 0.9739, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/biotransformation', 'display_name': 'Biotransformation', 'score': 0.7465037}, {'id': 'https://openalex.org/keywords/biocatalysis', 'display_name': 'Biocatalysis', 'score': 0.68388975}, {'id': 'https://openalex.org/keywords/enzyme-activities', 'display_name': 'Enzyme Activities', 'score': 0.493719}], 'concepts': [{'id': 'https://openalex.org/C197957613', 'wikidata': 'https://www.wikidata.org/wiki/Q407280', 'display_name': 'Cofactor', 'level': 3, 'score': 0.8127521}, {'id': 'https://openalex.org/C75520062', 'wikidata': 'https://www.wikidata.org/wiki/Q15321392', 'display_name': 'NAD+ kinase', 'level': 3, 'score': 0.7800971}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.7629512}, {'id': 'https://openalex.org/C27881333', 'wikidata': 'https://www.wikidata.org/wiki/Q864895', 'display_name': 'Biotransformation', 'level': 3, 'score': 0.7465037}, {'id': 'https://openalex.org/C33093398', 'wikidata': 'https://www.wikidata.org/wiki/Q174337', 'display_name': 'Flavin group', 'level': 3, 'score': 0.7410713}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.73910093}, {'id': 'https://openalex.org/C191503008', 'wikidata': 'https://www.wikidata.org/wiki/Q16007026', 'display_name': 'Biocatalysis', 'level': 4, 'score': 0.68388975}, {'id': 'https://openalex.org/C181647583', 'wikidata': 'https://www.wikidata.org/wiki/Q903429', 'display_name': 'Stereoselectivity', 'level': 3, 'score': 0.6678112}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.53904694}, {'id': 'https://openalex.org/C21951064', 'wikidata': 'https://www.wikidata.org/wiki/Q899212', 'display_name': 'Combinatorial chemistry', 'level': 1, 'score': 0.4465666}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.3100571}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.16892734}, {'id': 'https://openalex.org/C65024703', 'wikidata': 'https://www.wikidata.org/wiki/Q373406', 'display_name': 'Reaction mechanism', 'level': 3, 'score': 0.1542412}], 'mesh': [{'descriptor_ui': 'D000475', 'descriptor_name': 'Alkenes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009252', 'descriptor_name': 'NADPH Dehydrogenase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010088', 'descriptor_name': 'Oxidoreductases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000475', 'descriptor_name': 'Alkenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023281', 'descriptor_name': 'Genomics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009249', 'descriptor_name': 'NADP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009249', 'descriptor_name': 'NADP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009252', 'descriptor_name': 'NADPH Dehydrogenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010084', 'descriptor_name': 'Oxidation-Reduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010088', 'descriptor_name': 'Oxidoreductases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013237', 'descriptor_name': 'Stereoisomerism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cbpa.2007.02.025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S35563517', 'display_name': 'Current Opinion in Chemical Biology', 'issn_l': '1367-5931', 'issn': ['1367-5931', '1879-0402'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17353140', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/9', 'display_name': 'Industry, innovation and infrastructure', 'score': 0.4}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 69, 'referenced_works': ['https://openalex.org/W1601306260', 'https://openalex.org/W1684709410', 'https://openalex.org/W1964488453', 'https://openalex.org/W1968184993', 'https://openalex.org/W1978095193', 'https://openalex.org/W1983208597', 'https://openalex.org/W1984540569', 'https://openalex.org/W1986292144', 'https://openalex.org/W1988190862', 'https://openalex.org/W1989365081', 'https://openalex.org/W1996287439', 'https://openalex.org/W2001382343', 'https://openalex.org/W2001625405', 'https://openalex.org/W2004369824', 'https://openalex.org/W2010334495', 'https://openalex.org/W2010771263', 'https://openalex.org/W2017953332', 'https://openalex.org/W2021385460', 'https://openalex.org/W2021570983', 'https://openalex.org/W2023758242', 'https://openalex.org/W2024775043', 'https://openalex.org/W2028365046', 'https://openalex.org/W2032034337', 'https://openalex.org/W2032791629', 'https://openalex.org/W2038714833', 'https://openalex.org/W2039031426', 'https://openalex.org/W2039670084', 'https://openalex.org/W2050435569', 'https://openalex.org/W2050731295', 'https://openalex.org/W2053335601', 'https://openalex.org/W2053836836', 'https://openalex.org/W2055472776', 'https://openalex.org/W2055736690', 'https://openalex.org/W2063946699', 'https://openalex.org/W2066014603', 'https://openalex.org/W2066823304', 'https://openalex.org/W2067430855', 'https://openalex.org/W2069035747', 'https://openalex.org/W2069424964', 'https://openalex.org/W2071267290', 'https://openalex.org/W2072182353', 'https://openalex.org/W2078389018', 'https://openalex.org/W2080705038', 'https://openalex.org/W2082729684', 'https://openalex.org/W2088785063', 'https://openalex.org/W2100861430', 'https://openalex.org/W2106959676', 'https://openalex.org/W2116244634', 'https://openalex.org/W2121866971', 'https://openalex.org/W2122276118', 'https://openalex.org/W2125207215', 'https://openalex.org/W2131854841', 'https://openalex.org/W2145151567', 'https://openalex.org/W2146583027', 'https://openalex.org/W2149722012', 'https://openalex.org/W2160468220', 'https://openalex.org/W2161505664', 'https://openalex.org/W2164742212', 'https://openalex.org/W2168390874', 'https://openalex.org/W2168848189', 'https://openalex.org/W2171235753', 'https://openalex.org/W2227092953', 'https://openalex.org/W2327508408', 'https://openalex.org/W2949838441', 'https://openalex.org/W2951308364', 'https://openalex.org/W2952059213', 'https://openalex.org/W3135667157', 'https://openalex.org/W4234401333', 'https://openalex.org/W594321029'], 'related_works': ['https://openalex.org/W924188165', 'https://openalex.org/W4290012698', 'https://openalex.org/W4206172903', 'https://openalex.org/W2429842276', 'https://openalex.org/W2373828514', 'https://openalex.org/W2103643682', 'https://openalex.org/W2081009067', 'https://openalex.org/W2037702679', 'https://openalex.org/W1978861814', 'https://openalex.org/W1494880142'], 'abstract_inverted_index': {'The': [0], 'asymmetric': [1], 'bioreduction': [2], 'of': [3, 21, 34, 66, 69, 74], 'alkenes': [4], 'bearing': [5], 'an': [6], 'electron-withdrawing': [7], 'group': [8], 'using': [9, 52], 'flavin-dependent': [10], 'enzymes': [11, 81], 'from': [12], 'the': [13, 19, 24, 32, 67, 78], "'old": [14], 'yellow': [15], "enzyme'": [16], 'family': [17], 'at': [18], 'expense': [20], 'NAD(P)H': [22, 83], 'yields': [23], 'corresponding': [25, 79], 'non-racemic': [26], 'alkanes': [27], 'going': [28], 'in': [29, 85], 'hand': [30], 'with': [31, 77], 'creation': [33], 'up': [35], 'to': [36, 90, 94, 109], 'two': [37], 'chiral': [38], 'carbon': [39], 'centres.': [40], 'To': [41], 'avoid': [42], 'external': [43], 'cofactor': [44], 'recycling,': [45], 'this': [46], 'intriguing': [47], 'biotransformation': [48], 'was': [49], 'hitherto': [50], 'performed': [51], 'whole': [53], 'microbial': [54], 'cells,': [55], 'which': [56], 'frequently': [57], 'showed': [58], 'insufficient': [59], 'stereoselectivities': [60], 'and/or': [61], 'undesired': [62], 'side': [63], 'reactions': [64], 'because': [65], 'action': [68], 'competing': [70], 'enzymatic': [71], 'activities.': [72], 'Co-expression': [73], 'enoate': [75], 'reductases': [76], 'redox': [80], 'for': [82], 'recycling': [84], 'a': [86, 103], 'suitable': [87], 'host': [88], 'enables': [89], 'overcome': [91], 'these': [92], 'drawbacks': [93], 'furnish': [95], 'highly': [96], 'stereoselective': [97], 'and': [98], "'clean'": [99], 'C=C': [100], 'bioreductions': [101], 'on': [102], 'preparative': [104], 'scale': [105], 'that': [106], 'are': [107], 'difficult': [108], 'perform': [110], 'by': [111], 'conventional': [112], 'means.': [113]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2015164139', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 19}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 17}, {'year': 2017, 'cited_by_count': 18}, {'year': 2016, 'cited_by_count': 22}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 26}, {'year': 2013, 'cited_by_count': 25}, {'year': 2012, 'cited_by_count': 32}], 'updated_date': '2024-09-24T22:06:14.562565', 'created_date': '2016-06-24'}