Title: Streptococcus pyogenes superantigen SPEA expression suppresses all immunoglobulin classes in human tonsil explants
Abstract: Streptococcus pyogenes (GAS) superantigen expression is reportedly increased in GAS tonsillitis. This work investigated the regulation of superantigen streptococcal pyrogenic exotoxin A (SPEA) production by live emm1 GAS in a novel ex-vivo tonsil histoculture and cell suspension system, and the immune responses of tonsils to superantigens in this system.
Publication Year: 2010
Publication Date: 2010-11-30
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 1
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