Title: Vasoactive and inflammatory markers of neonatal bowel injury are suppressed by human milk gangliosides
Abstract: We established population-based reference limits for plasma total homocysteine (tHcy) according to creatinine.In 7042 middle-aged and elderly subjects from the Hordaland Homocysteine Study, we used statistical modeling to establish nomograms for tHcy according to creatinine in the whole population and in folate-replete and healthy subgroups.When plotted against creatinine, tHcy 97.5th percentile almost overlapped in men and women, and, in elderly, increased up to 8 μmol/L from the 2.5th to 97.5th creatinine percentiles. Folate-replete subjects had tHcy upper limits ∼ 20% below the whole population at all creatinine levels. Healthy subjects had lower creatinine, but at a given creatinine level, tHcy was the same as in the whole population.tHcy difference between men and women is mostly explained by creatinine. The tHcy-reducing effect of folate is independent of creatinine. In elderly people, creatinine should be taken into account when assessing tHcy levels.
Publication Year: 2008
Publication Date: 2008-10-01
Language: en
Type: article
Indexed In: ['crossref']
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