Title: Secondary gout associated with chronic myeloproliferative disorders
Abstract: The early recognition of acute gouty arthritis, prompt institution of colchicine and/or other antigouty inflammatory drugs, and the use of colchicine prophylactically during the interval periods are necessary measures for the control of secondary gout. The importance of administering allopurinol to prevent the extreme hyperuricemia and excessive hyperuricosuria in blood dyscrasias even before the onset of gouty arthritis should not be overlooked. However, the dosage of allopurinol must be titrated according to the degree of the hyperuricemia and of hyperuricosuria. The control of excessive hyperuricemia in patients receiving chemotherapy is particularly important. The side effects including its impact on the liver and the hemopoietic system should be kept in mind. It must also be remembered that the therapy may change the clinical course of secondary gout, but the course of the underlying blood dyscrasias may not be altered.
Publication Year: 1976
Publication Date: 1976-02-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 42
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