Title: PLASMA CONCENTRATIONS OF SEX HORMONES IN POSTMENOPAUSAL WOMEN IN NON‐ALCOHOLIC CIRRHOSIS
Abstract: SUMMARY Sex hormone and sex hormone binding globulin (SHBG) levels were measured in the plasma of postmenopausal women with non‐alcoholic liver cirrhosis ( n = 24) and compared with levels in matched controls ( n = 21). Plasma oestradiol was elevated: 80 vs 30 pmol/l, P < 0·005 (median values). Plasma SHBG was elevated, 15 vs 10 mg/dl, P < 0·001. Plasma dehydroepiandrosterone sulphate levels were low, 0·35 vs 2·0 μmol/l, P < 0·0005, as were plasma androstenedione levels, 2·5 vs 4·5 nmol/l, P < 0·05. There was no significant difference in plasma testosterone. These data suggest that liver disease per se alters sex hormone and sex hormone binding globulin levels in postmenopausal women.
Publication Year: 1985
Publication Date: 1985-10-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 18
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