Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1986979680', 'doi': 'https://doi.org/10.1016/s0022-5347(08)61137-4', 'title': 'LIPOXYGENASE INHIBITORS INDUCE DEATH RECEPTOR 5/TRAIL-R2 EXPRESSION AND SENSITIZE THE DU145 HUMAN PROSTATE CANCER CELL LINE TO TRAIL-INDUCED APOPTOSIS', 'display_name': 'LIPOXYGENASE INHIBITORS INDUCE DEATH RECEPTOR 5/TRAIL-R2 EXPRESSION AND SENSITIZE THE DU145 HUMAN PROSTATE CANCER CELL LINE TO TRAIL-INDUCED APOPTOSIS', 'publication_year': 2008, 'publication_date': '2008-03-21', 'ids': {'openalex': 'https://openalex.org/W1986979680', 'doi': 'https://doi.org/10.1016/s0022-5347(08)61137-4', 'mag': '1986979680'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0022-5347(08)61137-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101121273', 'display_name': 'Takumi Shiraishi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Takumi Shiraishi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109949960', 'display_name': 'Tatsushi Yoshida', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Tatsushi Yoshida', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002384546', 'display_name': 'Takashi Yasuda', 'orcid': 'https://orcid.org/0000-0002-7310-2492'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Takashi Yasuda', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109878052', 'display_name': 'Terukazu Nakamura', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Terukazu Nakamura', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101906773', 'display_name': 'Kazuya Mikami', 'orcid': 'https://orcid.org/0000-0003-3136-1354'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kazuya Mikami', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034053698', 'display_name': 'Natsuki Takaha', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Natsuki Takaha', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027885699', 'display_name': 'Mano Horinaka', 'orcid': 'https://orcid.org/0000-0001-8168-1802'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Mano Horinaka', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025287238', 'display_name': 'Susumu Nakata', 'orcid': 'https://orcid.org/0000-0002-9950-7543'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Susumu Nakata', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087829050', 'display_name': 'Ahmed E. Goda', 'orcid': 'https://orcid.org/0000-0001-8200-6104'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ahmed E Goda', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088978251', 'display_name': 'Akiyoshi Nishikawa', 'orcid': 'https://orcid.org/0000-0003-1379-8640'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Akiyoshi Nishikawa', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080691001', 'display_name': 'Yoichi Mizutani', 'orcid': 'https://orcid.org/0000-0002-5890-8172'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yoichi Mizutani', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052723519', 'display_name': 'Akihiro Kawauchi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Akihiro Kawauchi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013263645', 'display_name': 'Toshiyuki Sakai', 'orcid': 'https://orcid.org/0000-0002-7865-2258'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Toshiyuki Sakai', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113821547', 'display_name': 'Tsuneharu Miki', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Tsuneharu Miki', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 63}, 'biblio': {'volume': '179', 'issue': '4S', 'first_page': '388', 'last_page': '389'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9487, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9487, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/du145', 'display_name': 'DU145', 'score': 0.9444876}], 'concepts': [{'id': 'https://openalex.org/C2776438761', 'wikidata': 'https://www.wikidata.org/wiki/Q5206280', 'display_name': 'DU145', 'level': 5, 'score': 0.9444876}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7002374}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.66171026}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.5821781}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.4515008}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3916445}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.29673725}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29170603}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.14929989}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.13500917}, {'id': 'https://openalex.org/C2779723316', 'wikidata': 'https://www.wikidata.org/wiki/Q6459234', 'display_name': 'LNCaP', 'level': 4, 'score': 0.0797002}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0022-5347(08)61137-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.78, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3024235066', 'https://openalex.org/W2954788551', 'https://openalex.org/W2665045084', 'https://openalex.org/W2520591314', 'https://openalex.org/W2467627132', 'https://openalex.org/W2393489344', 'https://openalex.org/W2366783677', 'https://openalex.org/W2343596771', 'https://openalex.org/W2100046750', 'https://openalex.org/W2052103316'], 'abstract_inverted_index': {'You': [0], 'have': [1], 'accessJournal': [2], 'of': [3, 215], 'Urology1': [4], 'Apr': [5], '2008LIPOXYGENASE': [6], 'INHIBITORS': [7, 195], 'INDUCE': [8, 196], 'DEATH': [9, 197], 'RECEPTOR': [10, 198], '5/TRAIL-R2': [11, 199], 'EXPRESSION': [12, 200], 'AND': [13, 201], 'SENSITIZE': [14, 202], 'THE': [15, 203], 'DU145': [16, 204], 'HUMAN': [17, 205], 'PROSTATE': [18, 206], 'CANCER': [19, 207], 'CELL': [20, 208], 'LINE': [21, 209], 'TO': [22, 210], 'TRAIL-INDUCED': [23, 211], 'APOPTOSIS': [24], 'Takumi': [25, 55, 241], 'Shiraishi,': [26], 'Tatsushi': [27, 64, 248], 'Yoshida,': [28], 'Takashi': [29, 73, 255], 'Yasuda,': [30], 'Terukazu': [31, 82, 262], 'Nakamura,': [32], 'Kazuya': [33, 91, 269], 'Mikami,': [34], 'Natsuki': [35, 100, 276], 'Takaha,': [36], 'Mano': [37, 109, 283], 'Horinaka,': [38], 'Susumu': [39, 118, 290], 'Nakata,': [40], 'Ahmed': [41, 127, 297], 'E': [42, 128, 130, 298], 'Goda,': [43], 'Akiyoshi': [44, 138, 305], 'Nishikawa,': [45], 'Yoichi': [46, 147, 312], 'Mizutani,': [47], 'Akihiro': [48, 156, 319], 'Kawauchi,': [49], 'Toshiyuki': [50, 165, 326], 'Sakai,': [51], 'and': [52, 174], 'Tsuneharu': [53, 175, 333], 'Miki': [54, 177, 334], 'ShiraishiTakumi': [56], 'Shiraishi': [57, 242], 'More': [58, 67, 76, 85, 94, 103, 112, 121, 132, 141, 150, 159, 168, 178, 243, 250, 257, 264, 271, 278, 285, 292, 300, 307, 314, 321, 328, 335], 'articles': [59, 68, 77, 86, 95, 104, 113, 122, 133, 142, 151, 160, 169, 179, 244, 251, 258, 265, 272, 279, 286, 293, 301, 308, 315, 322, 329, 336], 'by': [60, 69, 78, 87, 96, 105, 114, 123, 134, 143, 152, 161, 170, 180, 222, 236, 245, 252, 259, 266, 273, 280, 287, 294, 302, 309, 316, 323, 330, 337], 'this': [61, 70, 79, 88, 97, 106, 115, 124, 135, 144, 153, 162, 171, 181, 246, 253, 260, 267, 274, 281, 288, 295, 303, 310, 317, 324, 331, 338], 'author': [62, 71, 80, 89, 98, 107, 116, 125, 136, 145, 154, 163, 172, 182, 247, 254, 261, 268, 275, 282, 289, 296, 304, 311, 318, 325, 332, 339], ',': [63, 72, 81, 90, 99, 108, 117, 126, 137, 146, 155, 164, 173], 'YoshidaTatsushi': [65], 'Yoshida': [66, 249], 'YasudaTakashi': [74], 'Yasuda': [75, 256], 'NakamuraTerukazu': [83], 'Nakamura': [84, 263], 'MikamiKazuya': [92], 'Mikami': [93, 270], 'TakahaNatsuki': [101], 'Takaha': [102, 277], 'HorinakaMano': [110], 'Horinaka': [111, 284], 'NakataSusumu': [119], 'Nakata': [120, 291], 'GodaAhmed': [129], 'Goda': [131, 299], 'NishikawaAkiyoshi': [139], 'Nishikawa': [140, 306], 'MizutaniYoichi': [148], 'Mizutani': [149, 313], 'KawauchiAkihiro': [157], 'Kawauchi': [158, 320], 'SakaiToshiyuki': [166], 'Sakai': [167, 327], 'MikiTsuneharu': [176], 'View': [183], 'All': [184, 341], 'Author': [185], 'Informationhttps://doi.org/10.1016/S0022-5347(08)61137-4AboutPDF': [186], 'ToolsAdd': [187], 'to': [188], 'favoritesDownload': [189], 'CitationsTrack': [190], 'CitationsPermissionsReprints': [191], 'ShareFacebookLinked': [192], 'InTwitterEmail': [193], '"LIPOXYGENASE': [194], 'APOPTOSIS."': [212], 'The': [213], 'Journal': [214], 'Urology,': [216], '179(4S),': [217], 'pp.': [218], '388–389': [219], '©': [220], '2008': [221, 235], 'American': [223, 237], 'Urological': [224, 238], 'AssociationFiguresReferencesRelatedDetails': [225], 'Volume': [226], '179Issue': [227], '4SApril': [228], '2008Page:': [229], '388-389': [230], 'Advertisement': [231, 342], 'Copyright': [232], '&': [233], 'Permissions©': [234], 'AssociationMetricsAuthor': [239], 'Information': [240], 'Expand': [340], 'PDF': [343], 'downloadLoading': [344], '...': [345]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1986979680', 'counts_by_year': [], 'updated_date': '2024-12-14T06:31:23.003618', 'created_date': '2016-06-24'}