Title: OP03.10: Prenatal MR evaluation of the fetus with a vein of Galen malformation; A Series of 5 cases
Abstract: An aneurysm of the vein of Galen represents the embryonic persistence of the median prosencephalic vein. A vein of Galen malformation is a complex arteriovenous malformation between the system of the vein of Galen and the cerebral arteries. There are wide variations in the arteriovenous connections. Multiple prognostic indices have been suggested for neonates with a vein of Galen malformation including presence or absence of hydrops, brain abnormalities, and cardiomegaly. Additionally, it has been proposed that the angioarchitecture of the vascular malformation might determine the perinatal outcome of the fetus. Multiple feeding vessels and dilated venous drainage would put the fetus at increased risk for congestive heart failure. We retrospectively reviewed the fetal MRI exams of 5 fetuses diagnosed with a vein of Galen malformation and correlated the findings with postnatal angiography and neonatal outcome. There were 5 neonates born with a vein of Galen malformation. 2 neonates expired within the first 2 days of life. These neonates had demonstrated hydrops and cardiomegaly on prenatal scanning, and were in congestive heart failure and distress following delivery. The remaining 3 fetuses underwent diagnostic angiography, and have undergone therapeutic embolization procedures of the vein of Galen malformation. In this small series the presence of hydrops and cardiomegaly had a direct correlation with poor postnatal outcome. Prenatal MRI demonstration of vascular architecture correlated with postnatal angiography.
Publication Year: 2008
Publication Date: 2008-08-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 1
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